Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59378	Epoxycholesterol	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	STAT5B; BTG1; RXRG; HMGA1; FOSB; MYT1; OSR2; SIX3; NR4A1; LIN28A; ELF3; EGR2; EGR3; EN2; ZIC3; ZBTB16; FOXA1; KLF4; ETS2; PTRF; ELF4; ZFP69B; ID1; BRD7; NFE2L3; FOSL1; NPAS2; TFDP2; SSX1; MEIS2; CBX3; ST18; POU5F1B; TULP4; LMCD1; ZFPM2; TEAD4; ATF3; CSDE1; EGR1; MXI1; REPIN1; ZNF12; SNAI2; SOX10; PHIP; INSM1; CTBP2; PBX1; RYBP; MYBL1; AHR; ZNF516; KLF6; ASCL1; CHD7; SOX17; MYCL; NR5A2; ZNF423; CDK7; TFAP2C; JUNB; TGFB1I1; SMAD3; MNDA; ZKSCAN1; ZNF430; TRIB3; HEY1; NAB1; TCEA2; SOX9; ZFP36L2; NR2F1; MSX1; CRK; BASP1; PUF60
Down-regulation	85	ZMIZ1; NFIC; C1D; IRF9; ZSCAN18; ZNF606; PMS1; IRF1; ZNF266; TOPORS; ZNF143; ZNF239; AES; JUP; SMARCA4; MAGED1; ERF; MED7; ZNF205; BRD2; MLXIP; EP300; KAT6A; ZFP30; RNF6; HMGA2; ZNF329; ZNF432; NEDD8; HMG20B; TRPS1; PEG3; MAFB; BRF2; ZFP64; BCL11A; CREB3; ZNF200; ZNF468; MEF2A; SPIB; ZNF783; CALR; SLC2A4RG; BRD4; HOXC4; SMAD5; ZNF562; CHD9; ZNF140; HIRA; ORC2; YBX3; MED1; LPIN2; ZNF587; NR1H3; ETS1; TLE4; NR3C2; NCOR2; CUX1; HOXC6; LITAF; IRF8; HIVEP2; BACH2; CRY1; HOXC10; TCF4; HMGB1; SMAD7; TRIM29; ASH2L; TBX3; SMAD1; NFAT5; ERBB2; RBL2; LEF1; WT1; NFIB; SMARCD2; NFKBIB; CEBPA