Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59374	Isotretinoin	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	HES1; BRIP1; NR4A2; TCFL5; CBX4; ZNF83; HIPK1; CBFA2T3; MAK; MLXIP; EGR2; TAF4; TAF9; PRPF6; NR1H2; PRDM2; JUNB; PBX3; CCNH; PRMT2; SRF; DACH1; LOXL2; ERBB4; PAX6; CREBL2; MAML1; CUX1; NRIP1; PIAS1; NCOA3; NKX2-1; PAWR; ACTL6A; MYB; ZHX2; NR4A1; ZFPM2; NHLH2; PHIP; DMTF1; ZNF302; ZIC1; RAD21; INSM1; ATF7IP; CEBPB; NANOG; EGR3; CSDE1; ZNF232; BRPF1; E2F5; PNRC1; MEIS2; FOXE1; RREB1; IRF8; ZNF573; WWTR1; ZBTB18; TOX3; ATF5; KLF10; KLF11; EGR1; FOXF2; CHD9; UBE2B; MED13; IRF7; NEUROD1; FOXO1; FOSB; PBXIP1; RUNX1; TRIB3; BACH2; SMAD1; ENY2; ZNF512B; TADA3; TULP3; CBX6; HHEX; HDAC9; CDK7; HEY1; RBPJ; OSR2; BASP1; ZKSCAN1; SCAND1; SETDB1; IFI16; TOB1; POU4F1; TOX; RBPMS; ID1; PHF20; TFAP2C; INSR; CRK; KDM5D; PUF60
Down-regulation	83	CDK2; SIX1; GABPA; FOXO3; TAF12; TGIF1; CDK9; STAT4; TRIM22; ADNP2; ELK4; CCDC59; SAP30; GATAD2A; PRRX2; SAFB2; NR1D2; ZNF329; MAGED1; ZSCAN18; THAP4; ZNF350; TFAM; ZBTB20; SF1; MED21; KLF2; DPF2; NCOA4; BCL11A; TCEA1; AATF; TAF10; YBX3; HIRA; STAT6; HMGB2; ERF; HOXC4; SMAD7; HIPK3; ZNF593; PA2G4; HMGB3; CTR9; RBM14; HOXB2; PFDN5; HTATIP2; ETS1; CREB3L1; DNAJC1; HIVEP1; SIX2; ENO1; REL; NR1H3; PTTG1; FOXD1; IRF6; MYCN; CEBPG; ARNTL2; GATA6; ZNF44; IKBKAP; MNAT1; HOXC10; GTF3A; PIAS2; PIR; HMGB1; MSX1; RCOR3; TCEA2; TXNIP; TCF4; HOXC6; NKX3-1; FOSL1; SMAD3; NFKBIB; CEBPA