Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59336	Osi-027	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	PPARD; PDLIM1; ZNF264; ZHX2; IRF9; SP110; ATF2; HES1; NR4A2; GATA1; CSDE1; KDM4C; SPDEF; PBXIP1; ZNF117; CREM; ZNF611; NR1H2; HIPK1; PAWR; HBP1; PNRC1; ZFPM2; CEBPD; POU4F2; SUPT6H; SP100; ZNF394; CDIP1; PBX3; INSM1; ZNF83; ZNF544; TFAP2A; ZXDC; ZNF43; MNDA; IRF7; FLNA; CREBL2; HMGA1; ZNF512B; ARID4B; NPAS2; VPS72; AR; KLF11; WWTR1; NFKB2; RAD21; CTBP1; TSHZ2; JUNB; TAF1; ZNF224; JUP; GFI1B; ZNF91; PRPF6; ZNF354A; RARA; HDAC9; ERBB4; ESR1; MTDH; TRIB3; RREB1; SMARCA1; MEIS2; MXI1; MED12; BNC2; ZFHX4; ZBED2; ZKSCAN1; URI1; HOXD1; TGFB1; TRIM16; KLF3; ZNF665; CTNNB1; SSBP2; PPP1R13L; TGIF2; ZNF44; ZNF562; COPS2; AHR; TDP2; ZFP36L1; SOX11; HEY1; ZNF136; ZIC1; ZSCAN31; IRF6; ETS1; KLF5; TCEA2; BCL11B; PIR; NR5A2; TP63; RBBP8; FOXG1; SETDB1; ZEB1; ZNF623; PEG3; SOX9; SOX17; TDRD3; NKX2-1; DMTF1; AEBP1; HHEX; CDC5L; KLF13; TCF7L1; WT1; MYC; MEOX2; EYA2; TFAP2C; CRK; BHLHE41; PUF60
Down-regulation	152	CCNA2; EED; SUV39H1; BRCA1; E2F2; GABPA; YBX2; ENO1; ZNF263; DDX54; CHAF1B; BCL6; PSPC1; HSF2; ZBTB48; E2F6; MTA2; KMT5A; TBL1XR1; UBE2I; ZNF84; BRPF1; PURA; BTAF1; NFIL3; NFYB; RBBP4; BRD8; TADA2A; USF2; TAF1D; ZNF226; YAF2; BRF2; RHOA; CREBZF; SAP30; GABPB1; ZNF764; KAT6A; MED4; KDM2A; ZNF384; ASH2L; DDX5; ZNF266; TFDP1; SAP18; IRF8; BATF3; RNF14; ID2; CDK8; TSC22D1; PRRX2; MAGED1; RAN; BLM; HOXC6; SIAH2; YBX3; BCLAF1; TCEB2; GATA4; CBX3; ELK1; PIAS2; NR2F2; TCF4; SMAD6; MED24; FOXD1; CBX6; ZBTB16; MED21; RUVBL2; BATF; TRIM32; DDIT3; HSBP1; HMGB3; ARID3A; NUP62; RBM14; ZBTB18; SMAD7; ZNF131; PHF8; AIP; SALL1; TBX3; ZNF107; LPIN2; PSMC3IP; ELF2; HMGB1; CDK7; PREB; ITGB3BP; TRIM28; MED1; ZNF516; HDAC1; XRCC6; ZMIZ2; EYA1; ZNF148; YBX1; HMGA2; KLF4; RBPMS; PATZ1; ING2; NCOA4; MAX; GTF3A; NEDD8; DNAJC1; ZEB2; ATF1; FOXJ3; TBPL1; FOSL2; HOXC10; SMARCE1; PITX1; KDM5D; HOXA1; ZNF281; MSX1; ETS2; PITX2; RBPJ; TLE4; SMAD4; JAK2; EGR3; ZMYM2; IKBKAP; EZH2; NKX3-1; MYCN; CITED2; MYCBP; MYBL2; SMARCD2; NFKBIB; FOSL1; SMAD3; BASP1; EGR1; CEBPA