Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59335	7,8-dihydro-l-biopterin	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	103	PDLIM1; STAT5B; BTG1; TRPS1; POU2F1; HIC2; SIX3; RAD21; INSM1; CDIP1; ZNF611; NR4A2; MECP2; ZNF264; ZNF83; MEIS2; VPS72; CHD4; STAT5A; CCNT1; DACH1; WNT4; SNAI2; FLNA; ZNF44; TBL1X; NLK; IRF1; HMGA1; NFKB2; AR; PIAS1; KLF13; HDGF; MXD1; ZNF160; BRD4; HDAC5; CAMTA2; PAX6; ZNF3; CBX7; ZNF711; ZNF12; PTRF; SMAD7; ZNF562; TOX; NCOA2; TEAD3; FOSL1; KLF5; RYBP; TCF7; ELF5; SMARCD3; TADA3; PHIP; MECOM; LZTS1; ZNF573; KLF10; FOXF2; PBXIP1; BRD2; ETS1; ZKSCAN1; ZNF224; OVOL2; ZNF721; MTDH; FOXG1; ATF3; ERBB4; TERF1; KLF11; CHD7; DMTF1; MYBL1; FOXF1; TFEC; TFAP2A; CEBPB; TGFB1I1; ZFPM2; RBPJ; TGFB1; ZNF623; EYA2; MNDA; TFAP2C; SOX17; SOX9; ZNF91; NKX3-1; PLAGL1; EGR3; HOXB2; TRIB3; RBPMS; BCL11B; CRK; PUF60
Down-regulation	79	CDK2; SAP30; BLM; GABPA; WDHD1; C1D; BRD8; HIF1A; ELF1; AFF1; PMS1; MLXIP; ZSCAN31; LYL1; SAFB2; USF2; HSF2; ID3; YAF2; THAP10; AES; HOXC6; EYA1; TGIF1; PPARGC1A; ZNF528; ZZZ3; STAT6; ARID4A; UIMC1; ZBTB18; PCGF2; RFX7; MAGED1; GTF3A; HHEX; POU2AF1; BAZ1B; BCL11A; ZNF432; ZSCAN18; ASCL1; FOXC1; PITX2; PIAS2; YEATS4; TRIM32; ECD; ZMIZ2; REPIN1; SF1; ARID5B; NCOA4; BATF; TTF2; NEDD8; SATB2; SMAD6; SIAH2; CERS6; PSMC3IP; NR2F2; TBL1XR1; HOXC10; PURA; WT1; MYCN; MXI1; ETS2; MAFB; TCEA2; NFKBIB; HEY1; PHF20; SMAD3; EGR1; SMARCD2; BASP1; CEBPA