Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59298	Vemurafenib	GSE92742	NPC	Human	24h	10uM	EID0333

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	CEBPZ; NR3C1; NR4A2; SNAI2; FOS; ZNF586; E2F6; VDR; NR1H2; ZNF467; VPS72; DLX2; CCNH; PSMC3; MEIS2; BACH2; KLF11; AHR; NFKB2; REL; PIAS1; NFE2L2; JUNB; ETS1; BCL11A; TTF2; LMCD1; WNT4; JUP; PEX14; SIX3; RAD21; ZNF331; EMX2; MYBL1; TRIB3; TFAP2A; IFI16; AR; WT1; PHIP; CEBPD; SIM1; PNRC1; HTATIP2; RARG; ZNF195; YBX3; RUNX1; OSR2; SMARCD3; PAWR; HHEX; SP140L; NR5A2; LITAF; BACH1; NFATC4; CREM; LOXL2; TFAP2C; HOXD3; CERS4; TCEA2; RBBP8; SHOX2; NR1H4; IRF6; ERBB4; PLAGL1; EHF; TEAD4; SUPT4H1; EYA1; MNDA; E2F8; RYBP; BCL3; NFE2; GATA6; OVOL2; TCF7L2; TOX; IRF9; SOHLH2; NR4A3; TRIM29; HBP1; ZFP36L1; TULP3; SOX17; ZEB1; ZFP36L2; PBX3; ELF5; CDK7; CEBPB; TCF7L1; AEBP1; SOX10; HOXD1; KLF4; ELF3; HEY2; NAB1; BHLHE41; HOXB6; HEY1; TWIST1; PUF60
Down-regulation	149	PCBD1; KDM4A; FOXO3; ZNF189; BCLAF1; USF2; POLR2A; RBM14; DDX54; MAGED1; ZKSCAN7; ZNF8; JARID2; CCNA2; TSC22D3; CARHSP1; NRIP1; HNRNPD; AES; TCF4; PHF8; TRIM22; KAT7; TBP; TADA2A; KDM2A; NFKBIA; ZNF813; DRAP1; YBX1; SUV39H1; MLX; BRD2; CLOCK; MAZ; ZNF606; RBBP4; CHD3; DDX5; SIX1; TLE2; FLNA; KAT6A; ZNF329; LPIN2; ZSCAN18; MYCBP; ZBTB18; PTTG1; ZMIZ2; BLM; ZIC1; HMGB2; NR1D2; NKX2-2; ZNF135; NEDD8; HDAC6; RNF141; TAF7; ING3; ARID4B; NCOR1; ETV1; SAP30; SIRT7; HLTF; TOX3; AFF1; HSBP1; BAZ1B; BMI1; FOXJ3; DEK; BRD3; ORC2; NPM1; RELA; SLC2A4RG; TCF12; CRY1; ZNF148; HMGB1; PIAS3; TBL1XR1; CD3D; REPIN1; ELK1; ASH2L; MAFB; DNMT3B; LIMD1; TRIM32; DNAJC1; MZF1; MED1; ZNF146; RCOR1; PIAS2; ZNF443; CTR9; INSM1; BIRC2; UBP1; IRF7; SMARCA4; ASCL1; PAX6; ERBB2; RBPJ; MED24; SFPQ; ENO1; NCOR2; FOXD1; MYCL; NCOA4; CBFB; TRIP6; C1QBP; ING2; NUP62; PATZ1; HMGA2; ZEB2; KLF2; SAP18; ATF4; HMBOX1; MSX1; SMARCA2; KDM5D; ZFPM2; CRK; NFIB; NKX3-1; FOXF1; TBX3; BCL11B; TXNIP; SMAD3; PCGF2; ELK3; HOXC6; EGR1; SMARCD2; NFKBIB; FOSL1; CEBPA