Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59274	Safinamide	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	70	EGR1; WNT4; FOXD1; KDM4C; FOSB; TFDP2; BMI1; HLTF; CSDE1; TRIM24; PIAS2; NFKBIB; PAX6; FOXN3; BATF3; PURA; KDM5A; ST18; TBPL1; PHF8; TCF12; RORA; BRPF1; FOXJ3; HIPK1; ZNF226; TADA3; CARHSP1; ZNF652; DNAJC1; SIAH2; FOXF2; PTTG1; ZNF532; SAP18; STAT1; PTRF; AEBP1; TXNIP; HTATIP2; MXD4; BBX; MYRF; RNF141; EGR2; NR4A1; BASP1; AES; RBPMS; ZIC1; SMAD6; USF2; IKBKAP; RUNX3; FOXA2; PIR; NKX2-1; LMCD1; HMG20B; ZBTB16; MSX1; KAT2B; YBX3; NKX3-1; HOXC6; TBL1X; TOX3; DNMT1; TCEA2; PBX1
Down-regulation	70	ATF1; SALL2; NFE2; TMF1; ZNF354A; NLK; ZNF91; PPARGC1A; ZNF12; FOSL2; ZNF117; ZNF93; NRIP1; SUPT7L; KDM5C; ZNF217; ZNF268; ZNF43; ZNF85; HEY1; MDFI; HOXD1; E2F3; NR3C2; CITED2; MYB; SCAND1; ERG; SLC2A4RG; WT1; SMARCC2; TRPS1; SNAI2; ZNF22; ZNF329; CREB1; TFCP2L1; CHD4; TRIM29; ZNF281; CREB3L2; ZNF124; JUP; ETV1; THAP10; EMX2; IFI16; TGIF1; VDR; ELK3; GMNN; STAT6; MAF; TRIM22; ZNF544; HOXA5; ZFHX4; TRIB3; TOB1; TFAP2C; MYCL; SATB2; NANOG; TP63; KAT6B; ZNF44; SSBP2; CDK7; ERBB4; NFATC4