Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59248	Lopinavir	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	FOXO4; EGR1; TCF15; FOXD1; ZNF205; TSC22D4; SSX3; ZNF646; MEF2D; SSX1; HDAC7; MZF1; FOSB; UBE2I; POU2F2; BTAF1; HOXD11; PA2G4; HOXB3; NKX2-8; SPIB; MYOG; TAF10; IRF5; HMX1; NFKBIB; SND1; MAZ; PHF1; TCF3; NPM1; PHF8; NFE2; KDM2A; ETV7; BRD8; BATF; MAX; CNOT1; MEF2A; PURA; EYA1; DNAJC1; NPAT; PITX1; IRF8; KLF2; ALX1; ARID5A; PKNOX1; HDAC4; DDX5; PITX2; POLR2A; EP400; TSG101; HOXC10; ZHX3; ID4; SNAI1; HLTF; NCOA1; JUNB; ZNF574; PIAS2; IRF3; CIC; IRF2; DNAJC2; NR4A1; TCF4; MKL2; CREB3L2; KMT2A; ZEB2; SETD2; RXRA; TULP4; HTATIP2; SIRT7; ZNF532; SRCAP; CDK8; ELK3; SALL1; CALCOCO1; YBX1; SMAD6; MAGED1; PTTG1; MLXIPL; VGLL4; NR1H3; CTR9; NONO; KLF9; CALR; ID1; BRD2; ZNF148; ZMIZ2; ST18; BAZ1B; NCOA4; ITGB3BP; BAZ2B; MSC; LZTS1; HSBP1; HOXC4; USF2; TCF12; JARID2; RNF141; CITED2; TSC22D1; SIX2; CARHSP1; IRF4; ERBB2; ZNF266; CD3D; SMAD7; EGR4; ZFP36L2; ELF5; LIN28A; FLNA; TOX3; MXI1; SMARCA2; STAT6; MITF; HMGA1; TGIF1; HOXC6; ZBTB16; HMGB3; RBPJ; ASCL1; PCGF2; HMGB2; MYC; AFF1; KLF4; ZMIZ1; SOX4
Down-regulation	137	PUF60; ZHX2; MNDA; ZNF91; HOXD1; BCL11A; ZNF467; ZNF34; ZNF43; PRKDC; TRIB3; HEY2; PEG3; SOX17; NR3C2; HOXD3; CNOT2; ZSCAN31; SFMBT1; URI1; ZSCAN12; ZSCAN16; ZNF665; PSMC3; NEUROD1; ZNF253; IRF9; CBFA2T3; ZNF669; MYBL1; BHLHE41; TP53; ZNF16; TFDP2; NFIB; HLX; ILF2; ENY2; ZNF443; WT1; EHF; HOXB6; ZNF32; RARG; CEBPD; CRK; ZNF117; WNT4; ZNF140; E2F5; KLF3; INSR; NKX3-2; COPS5; TOX4; ESR1; HDAC1; KLF11; DACH1; ZNF623; ZNF329; CDIP1; FOXM1; TCF7L2; CHD7; MAF; HSF1; ESRRG; RFC1; MTDH; PHF20; REL; HOXB5; CAMTA1; ZNF430; RYBP; HOXB13; MNT; CREB5; ETS1; L3MBTL1; SPDEF; ZNF93; ZNF415; LHX3; TGIF2; RAD21; CREB3; SUB1; TCEA1; ZNF611; REST; ZFPM2; TFAP2C; CCNC; TDP2; ZNF160; SMAD1; ZBTB18; SLC2A4RG; WWTR1; FOXO1; ETS2; PBX3; EMX2; AEBP1; RBBP8; PLAGL1; ZNF83; GATA6; ZEB1; ZNF44; HHEX; TFAP2A; C1QBP; BNC2; TBL1X; ERBB4; VDR; ERG; ELF4; ZKSCAN1; ZNF721; ZFHX4; VPS72; CEBPB; CREM; MECOM; MYCL; ZNF217; TRIP6; MEIS2; NFATC4; TCEA2; ATF5; FOXF1; MSX1