Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59233	Flupirtine	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	NUP62; PURA; BTAF1; NCOA1; SSX3; RNF111; KDM4A; KLF9; IRF5; CREB3L2; BLM; ARNTL2; HLTF; CTR9; MEF2A; ING3; JAK2; CRY1; UIMC1; SIAH2; ELK3; SFMBT1; ZZZ3; NR1D2; EZH1; CHD3; FOXD1; EGR1; DDX5; GATA4; ZNF652; SSX1; REPIN1; ELK1; PPARGC1A; SMAD3; MGA; ZNF629; SSBP3; SFPQ; PMS1; HIPK3; KLF1; ARID5B; CITED2; NCOA4; MAZ; UBP1; FUBP1; BATF3; ZNF672; HOXC10; MKL2; YBX1; MYCN; HIVEP2; ZBTB16; VEZF1; TBL1XR1; ZMYND11; ASH2L; CBX6; ZNF384; NRIP1; HOXC6; CD3D; ITGB3BP; PTTG1; RNF4; ZBTB40; RNF6; AFF1; FOXL2; ENO1; TSC22D1; MED1; YEATS2; ZMYND8; TRIP4; ZBTB38; ORC2; ZNF331; MEIS1; TCF20; ZNF148; BATF; USF2; RUNX1; NFYB; CARHSP1; MYC; RNF141; ZNF146; HMGA2; MTF2; CAPN15; TGIF1; RBPMS; DDX17; SMARCA2; NR4A1; STAT6; ZNF217; HMGB2; RXRA; PIR; SMAD4; SSBP2; ERBB2; ERG; YWHAB; KLF10; GTF3A; NKX3-1; BMI1; RBBP8; NR2F2; NCOR2; XBP1; ZEB2; MAFB; KDM5D; ZMIZ1; CRK
Down-regulation	113	PUF60; ARNT2; MNDA; ZHX2; HOXB6; POU1F1; ZNF350; PIAS4; TCF7L1; WNT4; BACH2; IRX4; ZNF623; TRIB3; PLAGL1; EHF; TEAD4; HSF1; IRF9; HEY2; SOX3; ZNF83; ESR1; ZNF7; HOXB7; ENY2; SOX11; POU4F1; CEBPD; PEX14; MEOX2; L3MBTL1; MAF; ZFHX4; ZNF91; BNC2; AR; ZNF432; RFXANK; ZNF250; ETV5; POU2AF1; TRPS1; PAX5; SOX17; TULP3; HLX; RAD21; ZNF117; DACH1; TFAP2A; CTNNB1; IKBKAP; ZNF423; ZBED2; KLF13; HOXB5; ERBB4; TLE4; ZNF573; TWIST1; MYB; SPDEF; SOX13; HBP1; ID1; ZFP36L1; NR3C2; ST18; CEBPB; INSM1; KLF5; LOXL2; HIF1A; MEIS2; PBXIP1; SCAND1; ILF2; TCF7L2; OSR2; MAGED1; LHX3; HOXD1; GATA6; SMAD1; TERF1; SREBF1; HHEX; NR1H2; ISL1; MYRF; FOXA2; TDP2; TFAP2C; ID3; FOXO1; MED24; BHLHE41; SNAI2; AEBP1; WT1; INSR; HOXB2; TBX3; PBX3; TOX3; FOXG1; PEG3; BASP1; NFATC4; TCEA2; PBX1; YBX3