Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59209	Lithocholic-acid	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	106	ABL1; TBX2; CREB3L2; ELF1; CBFB; DEAF1; SIAH2; ELK3; HLTF; RYBP; MEIS1; PPARGC1A; JARID2; IRF5; ZFHX3; TXNIP; ZHX3; PCGF2; ZNF24; CRY1; KLF2; SSX1; PIAS3; FOXK2; HIPK3; TRRAP; MITF; PIR; CTR9; RCOR3; ETV5; MEOX1; PHF8; JAK2; ZNF652; HMGB1; MKL2; FOXJ3; ZBTB18; SP3; HEY2; ZMYND11; BBX; JUND; MED21; GATAD2A; STAT6; PURA; ZBTB38; NRIP1; SMAD2; SUB1; PEG3; PITX1; WWC1; ZEB2; HIPK1; CEBPB; PHF2; SIN3B; MBD2; SMARCA4; YBX1; REPIN1; MED13; TRIM16; NPM1; TSC22D2; MYC; MEOX2; SMARCA1; BMI1; HMGN3; HMGB2; FOXJ1; MED24; LITAF; MSX1; TSC22D1; SMARCA2; MAFB; ASCL1; ETS2; ITGB3BP; SHOX2; SMAD4; CCNE1; XBP1; ID2; ZFP36L1; ZBTB16; MED1; ZNF423; PRRX1; AFF1; CBX6; NR2F2; EYA2; TOB1; HDAC9; KLF4; SOX9; ZIC1; SATB2; CRK; ZMIZ1
Down-regulation	84	HOXA1; BCL11A; TFDP2; TOX4; TRIB3; SALL2; MED20; BNC1; TBX19; HOXD1; RHOA; SPIB; ING4; HOXC13; VDR; OVOL2; GCM1; ATF4; CALCOCO1; NR1D2; KLF5; MED14; IRF1; TOX3; ZNF266; ZHX2; IRX4; COPS5; HOXB7; MYRF; L3MBTL1; PAWR; DMTF1; HR; RUNX1; ZNF133; ZNF165; BTG1; WT1; CALR; HOXB13; CEBPD; CDK9; GFI1; TRIM29; ZNF117; DLX2; TCF7L2; IRX5; TP63; TFAP2C; DDIT3; DDX17; SOHLH2; RNF14; ETS1; PAXBP1; KLF10; TFAP2A; APEX1; NANOG; TDP2; ZNF232; HEY1; ZNF532; TCEA1; ENO1; ZNF589; ZBTB20; ELF4; NCOA2; INSM1; HOXC10; TWIST1; INSR; DACH1; POU4F1; ZNF44; ID1; VPS72; FOXG1; NFATC4; MEIS2; SOX10