Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59199	7,8-dihydro-l-biopterin	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	EGR1; KLF9; TBX2; WDR77; ESR1; FOS; PEG3; PREB; FOSL1; CBX6; KAT8; SRCAP; HIPK3; IFI16; NEUROD1; ERCC3; STAT5B; BATF3; CARM1; CLOCK; DDX5; SMARCD2; RBFOX2; NAB2; GATA3; ZNF629; ZNF516; MAFF; SMAD3; ST18; STAT6; MKL2; OSR2; MEIS1; TLE2; PMS1; FOXK2; CBX7; EGR3; KLF2; TGFB1I1; SHOX2; EGR4; CCNC; GCFC2; CAPN15; CD3D; PCGF1; ZNF32; GATA4; MSX1; HOXB2; ZNF83; MYT1L; MED21; HOXB7; ETS1; MLX; NR4A1; SUB1; REL; PURA; SPIB; AEBP1; CCDC59; TULP3; DDX17; IRF2; FOSB; EMX2; TAF11; HOXA5; NPM1; NR2F2; HDAC9; EED; NCOR2; SND1; KLF4; RUNX1; RXRA; EZH2; XBP1; KLF10; CUX1; SMAD7; ZFPM2; CARHSP1; MYC; COPS2; DLX5; HLF; IRX5; ERBB2; ID1; HOXC10; HOXC6; ZIC1; TCEA2; CRK
Down-regulation	119	PUF60; MNDA; ZNF623; SFPQ; SP2; HOXD1; BIRC2; ZNF7; MYCBP; HOXD3; ENY2; ZNF34; NR3C2; TSC22D4; SAFB; HEY1; BRCA1; SALL2; TRIM29; MED16; E2F3; ZNF250; DMTF1; GTF2A2; ZNF43; ZFHX4; ZNF16; TP63; HIPK2; SIX3; BRCA2; MYRF; ZFP30; URI1; ZNF93; NPAT; ZNF358; KLF5; IRX4; PSMC3; HMG20B; PEX14; SIRT2; RELA; YBX1; HEY2; MYCN; HSF1; NR5A2; HMGN3; MXI1; CTR9; ERBB4; PPP1R13L; CTNNB1; TERF1; PAWR; ATF7IP; TCF7L1; ZNF184; DACH1; ILF2; MYCL; RAD21; MYB; NKX2-2; TFCP2L1; NR2F1; ESRRG; BACH2; MYBL1; ASCL1; NCOA2; SOX9; RCOR1; PBX3; PLAGL1; NFIB; CDYL; BCLAF1; TDP2; SMARCA5; NEDD8; EYA1; BHLHE41; TFCP2; TLE4; HIF1A; TCEA1; SOX10; ZBED2; TCF12; CENPF; TOX3; TBPL1; ELF5; MTF2; ID2; BRD4; SNAI2; CHD7; ZNF264; HMGB1; ZBTB18; ZNF611; YWHAB; FOXC1; SMAD1; BASP1; CTBP2; FOXG1; FOXF1; ATF5; ZNF160; SATB2; TSC22D1; ZNF423; NFATC4; TRIM22