Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59163	Motesanib	GSE92742	NPC	Human	24h	10uM	EID0332

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	PPARD; GFI1B; TXNIP; ZNF263; NFE2; LEF1; HSF2; JUNB; ZBTB18; ST18; PIAS4; CCNT1; STAT6; CLOCK; TCF7; ZSCAN18; JAK2; NLK; ELK3; IRF9; ARL2BP; TCEB2; ZSCAN31; MAZ; AES; ZNF165; BAZ2A; SP3; SSX1; KLF1; TSC22D2; NKX2-1; ZNF135; AFF1; PHF1; TRIM28; PITX1; MXI1; MLXIP; MXD4; CHD1; UBE2B; BACH1; RFX7; ZNF274; TFEC; JUP; HDAC4; PBXIP1; BAZ2B; PSMC3; ZNF217; CCNC; ZNF83; HMGA1; SIAH2; CNOT6; CEBPB; AHR; GRHL2; ZFP36L1; BCL11B; RFX5; HHEX; HIC2; ZNF551; IRF6; TAL1; ZFP36L2; CD3D; ZNF512B; CUX1; FLNA; MAFB; HOXB2; BTG1; FOXA2; CDK7; HMG20B; ESR1; PCGF2; ID1
Down-regulation	97	SPEN; ZNF91; TBX10; BCL11A; LOXL2; ZNF85; HEY1; SNAI2; KLF6; BLM; CSDC2; JUN; SALL2; DACH1; TBX1; HOXB13; IFNB1; PITX3; ZNF43; EPAS1; HOXB6; ETS1; ZNF93; BHLHE41; POU5F1B; HDAC1; MECOM; CBFB; NR2F1; CENPB; HDAC7; ZNF430; TCF21; ZBTB16; GFI1; MAFF; SOX13; FOSB; CITED1; KLF5; ZBTB38; TLE4; CBX3; MAF; HOXB7; CREB5; FOXL2; TBX21; MEIS1; NPAS2; MYCBP; PTRF; MYRF; PMS1; TCF7L1; ZBED1; RNF4; RORA; ATN1; LPIN2; APEX1; DDX17; ZNF107; MSC; CITED2; EGR2; EGR3; SIX1; INSM1; MNAT1; FOSL2; SALL1; TCF4; HOXC10; KLF9; SMAD2; BNC2; ENO1; ELF5; FOXF1; TOX; FOXO1; SOX10; MEIS2; TRIP6; HOXA5; ZNF44; TCEA2; PBX3; FOXG1; NR4A2; TRIM29; ZMYND8; ID3; NFATC4; PBX1; MSX1