Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59102	Flupirtine	GSE92742	NEU	Human	24h	10uM	EID0331

Response Information :

Types	Number	Response transcription factors
Up-regulation	158	NFATC3; MNAT1; NFE2L2; ZNF331; HES1; SOX13; SKI; SSBP3; LITAF; BARX1; PPARA; TBX1; TP73; TAF1; ELF4; WDR77; KLF3; IRF9; ZNF117; CCNH; EYA2; ANKRD1; ZNF586; THRA; KLF11; YEATS4; MAFF; KLF10; BNC1; ZNF222; LHX3; FOXF2; KDM5C; LOXL2; TULP3; SKIL; MED21; E2F4; ZNF239; CREB3L2; BACH2; IRF6; SPDEF; SIN3B; NR4A2; WWP1; THRB; PNRC1; NR1H2; ETS1; ELK4; HDAC9; DDIT3; TRPS1; CALCOCO1; MDM4; ELF5; PBXIP1; TFAP2A; GATA6; TCF7L2; EPAS1; HOXC10; ZNF544; BCL11A; CEBPB; SOX9; ZNF232; NFE2L3; TFCP2; CDK9; NFATC4; SHOX2; CDIP1; RAD21; RFXANK; SOX17; PRRX1; HBP1; RXRA; HOXC5; EN1; MED14; FOXE1; NFYA; STAT6; RARG; PRDM14; PPP1R13L; ACTL6A; COPS5; ATF3; FOXI1; NR0B1; HHEX; HOXA1; ZNF394; MYBL1; PCGF1; MEIS1; ZNF195; HIPK2; TTF2; MYBL2; THAP10; E2F8; ERG; ZNF350; TRIM25; TCF7L1; SSBP2; VGLL1; ATF5; JUNB; SMAD7; RUNX1; TBX21; TCF21; CBX7; MYRF; CSDE1; KLF13; KAT2A; ETV5; RBL2; VPS72; NR0B2; SNAI2; CALR; TEAD3; FOXG1; SMARCA2; JUP; NFE2; TOB1; BNC2; KLF4; CEBPD; JAK2; TAL1; PDLIM1; ETS2; RBM39; IFI16; FOXA2; FOXJ1; MKL2; JUN; KLF9; ZFP36L1; TGIF1; PITX1; ZSCAN18; PSMC3; HEY1; HOXB2; PEG3; TCEA2
Down-regulation	190	PUF60; CRK; SOX4; PSMD9; TOX3; BASP1; CERS6; MAGED1; DPF2; ZMYM2; SNW1; TSC22D1; TRIM28; SMAD4; RBM14; EN2; DRAP1; MED6; SMARCD3; NEDD8; ARID4B; EDF1; BAZ2B; TCF12; NCOA6; SP3; ZKSCAN1; SMARCA4; USF2; ZMYND8; MTF2; SMARCC1; PSPC1; ZNF189; RNF10; RXRG; NR2C1; NHLH2; PBRM1; CTBP1; HDAC2; POU2F1; CTR9; KDM4A; ERBB2; HDAC6; UBP1; NCOR2; YWHAB; SMAD2; RNF4; ZNF248; KDM5A; NONO; NFIB; ASCL1; KMT2A; EYA1; RCOR1; ZNF146; ZMIZ2; ZNF292; BIRC2; HLTF; WWC1; BMI1; SFPQ; SAP30; ZEB2; CITED1; ZBTB24; HMG20B; BRD8; ENO1; HSBP1; PSIP1; ETV1; PTTG1; NR2F2; ALX1; TBL1XR1; BRD3; CHD9; IRF4; RFX5; CUX1; RUVBL2; SETD2; CNOT6; PATZ1; MYT1L; ZNF24; TULP4; SMARCE1; ZNF721; ZNF672; ZBTB38; ZNF302; MYT1; CBX3; NCOA4; ZNF44; PHF20; ZIC1; CTBP2; TBP; BCLAF1; JARID2; ZFP64; ZNF419; ZNF711; HMGN3; KAT7; PCGF2; TCF7; ZNF536; ELF2; TLE4; CLOCK; NELFB; MED23; RBBP4; TCF4; RSF1; PLAGL1; EP400; HNRNPD; NAB1; ZNF148; MGA; EZH2; ZNF410; ZNF443; ZNF160; BRPF1; POLR2A; SOX2; RAN; MXD4; PHOX2B; ZNF430; SREBF1; ZNF423; LEF1; ZNF23; BAZ1B; RBBP8; BRD4; MAML1; ATF4; DNMT3B; KDM5D; ZBTB18; MED1; SMARCA5; SMAD1; RORA; PIAS2; NKX3-1; IKBKAP; TRIM32; FHL2; MYCBP; KDM2A; HOXB7; FOXD1; TBL1X; ING2; ISL1; DNAJC1; NR1I2; HOXB13; HOXD1; NUP62; BCL10; CARHSP1; TCEB2; CRY1; SOX10; RBPJ; RUNX3; SUB1; CCNA2; MYB; MED24; MAF; MSX1; CREG1; KAT6A; TLE1