Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59067	7,8-dihydro-l-biopterin	GSE92742	NEU	Human	24h	10uM	EID0331

Response Information :

Types	Number	Response transcription factors
Up-regulation	101	SUV39H1; PBXIP1; SUPT3H; IRF9; CCNH; IRF6; RAD21; SOX13; KDM5C; TBX1; SSBP3; NFATC4; TAF1C; ARID5A; RORC; TGFB1; CRYM; VPS72; ZNF22; HES1; ERG; KLF15; THRA; ATN1; JUP; E2F8; MYBL2; MAFF; MED25; SSBP2; KLF9; OSR2; DLX4; YEATS4; ELF4; FOXA2; AR; KAT2A; CEBPB; ETS1; EN1; KLF13; ZNF331; RUNX1; ACTL6A; ZNF117; GFI1; PHIP; FOXF2; EPAS1; PSMC3; TBX21; RUVBL1; HOXA11; ZNF589; ZNF232; TCF7L2; BCL11A; HTATIP2; ZNF557; ATF3; CD3D; CNOT3; MED17; CALR; VGLL1; ATF5; PRDM1; HDAC9; CBFA2T3; AEBP1; MYBL1; SOX9; TBX3; HOXC10; TAL1; NAB2; FOXJ1; SNAI2; ZFP36L2; NFE2L3; LMCD1; NR1H3; KLF6; MYB; RBL2; FOXL2; ZNF195; PIR; ETS2; HOXB5; IFI16; MYRF; HOXB6; ESR1; CEBPD; MXI1; MNDA; BHLHE41; HEY1; HOXB2
Down-regulation	160	SOX11; ARID4B; BASP1; RFX5; TOX3; NONO; ZEB2; SMAD4; TLE4; BRD3; MBD2; CAMTA1; NRIP1; CTR9; MAGED1; YBX1; RBM14; ZFHX4; NR2F6; PTTG1; HIVEP1; ETV1; RBBP4; ZKSCAN7; SMARCA4; EDF1; EP400; ID2; BPTF; MED6; SMARCD3; CHD7; ELF5; GTF2IRD1; HNRNPD; NLK; SPEN; TBL1X; CHD3; SMAD2; REPIN1; DEK; ZNF292; PHOX2B; RAN; ARID4A; NFIB; RCOR1; BAZ2B; ASH2L; ZNF189; DR1; E2F5; HLTF; ZMYM2; KDM4A; UBE2B; ZFP64; KMT2A; TCF4; CRK; INSM1; KAT7; USF2; BRPF1; BCL10; WWC1; LZTS1; TRPS1; ATF4; BAZ1A; MYT1L; ZMYND8; KLF2; RERE; RNF10; MAX; ZNF672; ZBTB38; JARID2; ISL1; TULP4; ZNF783; HMG20B; PBRM1; MEIS1; ELF2; SFPQ; SMARCA1; SETD2; NFKB1; CITED1; NRBF2; RBBP5; BIRC2; TRAK1; MTF2; SIM2; ZNF43; BAZ1B; TRIM32; TBPL1; CREB1; ZNF516; CENPF; ADNP; RNF4; TP53; NCOA4; SMAD1; RBBP8; MEOX2; SOX10; ZNF148; DNMT3B; IL16; ENO1; UBP1; PATZ1; SREBF1; BCL3; PITX1; ZNF512B; PBX1; SPIB; TADA3; ZNF532; TAF10; TRIM24; TMF1; KLF5; TSC22D2; JUND; BRD8; CREB3L1; SMARCA5; DNAJC1; CBX3; ING2; DDX17; PCGF2; ASCL1; LEF1; NCOR2; PBX3; PEG3; KDM2A; ID1; KDM5D; SIX1; MSX1; SIAH2; ZBTB18; CARM1; NUP62; MAF; CCNA2; CREG1; DAXX; USP22