Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59060	Celastrol	GSE92742	NEU	Human	24h	10uM	EID0331

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	FOS; EGR1; HES1; NFATC3; DDIT3; FOSB; YEATS4; BAZ2A; SUPT3H; ERG; ETS1; JUNB; SNAI2; SOX13; ZNF345; RAD21; NR4A2; ZNF22; TTF2; CD3D; ACTL6A; HBP1; PROX1; TAF9; VPS72; IRX4; BRIP1; ZNF331; CEBPB; LEF1; TLE2; ZNF117; MED13; NR1D2; TCF7L2; E2F4; SPDEF; IRF9; BARX1; ATF3; ZNF107; E2F8; ZNF124; PNRC1; IRF6; EN1; TGFB1; SRCAP; HDAC9; ELF5; VDR; CREB3L2; ZNF85; PRDM14; ZNF415; ERBB4; SOX17; JUND; KLF7; FHL2; EGR4; RUNX1; TWIST1; KLF2; PBXIP1; TAF1A; TBX3; CBFA2T3; ELK4; CDIP1; MYBL2; ZNF224; CCNT1; ZBTB20; MDM2; RSF1; MYB; AEBP1; GATA6; NKX2-1; PCGF1; TAL1; MED14; EHF; SSBP2; SOX9; ZNF10; ESR1; KLF9; ZNF557; PROP1; NR0B2; NR4A1; SKIL; ZNF544; IFI16; KLF13; EGR2; RXRA; KLF11; ZNF232; REL; ZNF665; PRRX1; DACH1; TRPS1; ZNF93; NR0B1; JUN; ZNF195; MLXIP; INSR; TULP3; ZNF589; FOXA2; ZEB1; HHEX; VGLL1; MYC; BCL11B; ST18; MYBL1; PGR; ZNF217; ARID5B; KLF10; MXI1; PAWR; SOHLH2; TFAP2A; HIRA; ZNF551; ZFP36L2; HOXD1; SATB2; LMCD1; NFE2L3; NFATC4; PBX3; CEBPD; TP63; JUP; ZNF165; CBFB; CCNE1; ZNF394; ZSCAN18; PSMC3; MYCL; PURA; BHLHE41; ID4; ID3; ID1; CALR
Down-regulation	171	PUF60; SOX4; CTBP1; BASP1; APEX1; SNW1; HDAC1; RBM14; TAF12; KAT7; EDF1; PREB; KAT5; DRAP1; MAGED1; OLIG2; YWHAB; ASH2L; TLE4; ENO1; USF2; RUVBL2; TRIM16; SMARCD3; DPF2; NEDD8; FOXO3; CTR9; SUV39H1; RBBP4; CRK; NCOA6; NELFB; ZNF226; ALX1; ZNF45; TRIM28; PIAS3; DEAF1; SMARCA4; ERBB2; LOXL2; PQBP1; HSBP1; PARP1; SAP30; HMG20B; ZMIZ2; SOX2; BRPF1; WWC1; KDM5A; PKNOX1; HNRNPD; ZEB2; PSIP1; FOXF1; SMARCC1; ZNF248; RBPJ; NONO; HR; HDAC2; ZKSCAN7; VEZF1; WHSC1; BMI1; RNF4; KDM4A; MYT1L; MLX; MED16; CENPB; PCGF2; PSPC1; TBP; YBX1; HMGB2; ZMYND8; WWTR1; ZFHX4; EP400; SP110; NCOA4; RFX5; MAZ; RCOR1; TBL1X; SMAD2; ZIC1; BRD3; PITX1; ZNF384; EYA1; UBP1; NCOR2; ZNF672; SMARCA5; PTTG1; SCAND1; TRAK1; GTF3A; PATZ1; DDX54; PSMC3IP; MED23; TCF4; SMARCE1; HDAC6; HLF; RNF10; BAZ2B; NFE2L1; BCLAF1; TAF10; NAB1; BRD8; LPIN2; RARA; HAND1; DR1; ZMYM2; KDM2A; ZBTB1; JARID2; TFEC; PIAS2; ING2; NKX2-2; DNMT3B; ID2; KAT2B; PLAGL1; EP300; ZNF23; PHF8; BRD2; TCF12; NFKB1; NFYC; TADA3; ZNF146; ATF4; ZBTB18; FOXD1; NUP62; MED24; SFPQ; PIR; FOXG1; TCEB2; HOXB7; FLNA; SOX10; CARHSP1; MITF; MYCBP; CARM1; TRIM32; HLTF; TCERG1; POU4F1; MAF; CCNA2; TAF1D; NR2F2; RREB1; DAXX; VGLL4; DNAJC1; CREG1