Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59026	Vemurafenib	GSE92742	NEU	Human	24h	10uM	EID0331

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	NFATC3; SUPT5H; TGFB1; HES1; MBD2; ZNF22; ELF4; RFXANK; MED12; KLF9; SSBP2; SPI1; ACTL6A; KLF13; VPS72; RXRA; HBP1; TRPS1; ZBTB7A; SNAI2; MKL2; EPAS1; IRF9; CBX6; AR; PTRF; DBP; NR1D2; NFATC4; RNF6; RBBP8; E2F8; TCF3; TULP3; CCNH; LMCD1; MED25; ID4; CDYL; ZNF85; NUP62; TFAP2C; MAGED1; BCL6; ZNF224; CNOT3; ERF; ESR1; IRF6; FOXO1; PRDM1; KAT2A; ZNF267; ZNF117; TAL1; MYC; ZNF331; ZNF444; ETS1; ZNF264; TEAD4; EGR2; ZFP36L2; MNT; AGO2; SMAD7; BCL11A; ZBTB16; CEBPB; SUZ12; ZNF232; NFAT5; ZNF580; ZNF217; BTG1; KLF5; MAFB; ZFP36L1; SERTAD2; AFF1; MXI1; RUVBL1; CRY1; GATA6; ERBB4; CARHSP1; CCNE1; FOXG1; HOXB2; WT1; MYBL1; CEBPD; RREB1; CALR; MNDA; MECOM; PSMC3; IFI16
Down-regulation	84	FOSB; HDAC1; ZBTB18; ASH2L; ZEB2; BTF3; KAT5; PHOX2B; ALX1; NPM1; GLI3; KLF2; ATF4; ZNF528; ZNF536; HOXA1; HDAC2; PATZ1; HMGB2; BAZ2B; ETV5; PFDN5; CBX5; UBE2B; MYCN; NFIB; TRIM22; NONO; RBBP4; YBX1; ISL1; CTR9; BRD2; EDF1; CBX3; SALL1; TFEC; CRK; ZNF23; ERBB2; CTNNB1; ZIC1; HAND1; RBBP7; TLE4; PPARGC1A; EYA1; FOXF1; ELF1; LZTS1; EGR3; HNRNPD; HLTF; ZNF177; ZNF268; NCOA4; PAX5; XRCC6; KAT2B; DDX5; SFPQ; PITX1; SND1; ELF3; ELK3; MYCBP; FOXD1; NR4A1; TSC22D2; SMARCA2; PIR; TADA3; SMARCA5; BASP1; CREB5; FHL2; HHEX; PCGF2; ZNF423; JARID2; CREG1; MED24; MSX1; CCNA2