Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID59006	Safinamide	GSE92742	NEU	Human	24h	10uM	EID0330

Response Information :

Types	Number	Response transcription factors
Up-regulation	104	ZNF586; HOXA10; ZSCAN18; ZNF134; TEAD4; LMX1B; ZNF587; ZNF551; HOXC13; DLX2; DBP; HOXA11; HOXD10; HOXA3; ZNF93; ZNF544; ZNF329; NFIC; MXD1; PNRC1; SMAD6; KDM5D; TLE4; MED20; BACH1; ZNF264; SALL1; MAFB; KLF9; FOXD1; MZF1; CDIP1; ZNF394; NFIX; RCOR3; FLI1; ARID3B; ZNF211; SIM1; MECP2; EGR2; KLF13; NFKBIA; ZNF304; TAF12; CNOT3; ID1; PBX2; ELF4; PREB; CBX6; KLF6; SIM2; ENO1; OSR2; NR1H3; NR2F2; JAK2; NAB2; RNF4; FOXF1; ECD; HIRA; TWIST1; ZNF217; TAF7; ERF; TRIM22; EP300; MEOX1; AHR; TBX3; FOXF2; ZBTB20; SLC2A4RG; PTTG1; CEBPB; TRIP6; HOXD11; DDIT3; RXRA; MITF; SOX9; HOXC10; CEBPG; MNDA; CITED2; ID4; FOXC1; DACH1; TRPS1; ID3; RUNX1; ZNF611; PRRX1; AEBP1; KLF5; ZNF160; PHIP; FLNA; NFATC3; TGFB1; EYA1; HOXB2
Down-regulation	110	NR2F6; BACH2; PHOX2B; CERS6; CXXC1; MYT1L; ZNF107; PKNOX2; TCF12; KDM2A; SF1; ZNF24; SOX11; ZFPM2; ZNF536; ELK3; E2F5; VEZF1; TCF4; PBX1; HLTF; ADNP2; SETD2; TRIM24; PCGF2; SP3; TSC22D4; USF2; HIVEP1; ZEB2; FOXO3; AIP; SFPQ; PIR; ZNF302; BPTF; ANKRD1; SUZ12; NFIB; MEOX2; FOXE1; IRF1; BIRC2; PHF8; ZNF410; RBM14; MYB; CLOCK; BMI1; SATB2; ZNF268; CHD7; RNF138; FOXO1; OLIG2; STAT5A; TRRAP; CRY1; TULP4; ERG; SMAD2; SOX13; HIPK1; RHOA; SSX1; LHX2; CSDE1; BCL10; POU2AF1; IRF4; MYC; PRKDC; MED1; INSR; KLF2; CDK7; CREM; HEY2; KAT2B; CHD4; ZNF528; HMGA1; RORA; MAGED1; HIVEP2; CHD9; SALL2; NCOA2; ST18; ELF3; MYRF; JUNB; ZEB1; MLXIP; TSC22D2; TOX3; TCF7L2; BASP1; ZBTB18; HHEX; FOSB; ZMYM2; WT1; PEG3; TSC22D1; BHLHE40; ZNF423; PAX5; GATA6; BTG1