Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58984	Pirarubicin	GSE92742	NEU	Human	24h	10uM	EID0330

Response Information :

Types	Number	Response transcription factors
Up-regulation	156	EGR2; VDR; POLR3C; TFAP2C; NFRKB; CEBPA; HTATIP2; CBX4; TOB1; TTF2; ZNF200; ADRB2; HLX; NKRF; HES1; E4F1; ZNF222; KLF4; ELF4; HOXD1; ZNF211; ETV6; ZNF85; ZNF354A; KLF11; CAPN15; PBX3; BLZF1; IRF7; ATF3; ZNF500; KAT2A; SNAPC4; ACTL6A; TBX2; MAFB; NFKB2; TOX4; EGR1; GON4L; CIR1; ZNF239; TOPORS; TSC22D3; CEBPB; MED6; EN1; PTRF; ARNTL; TMF1; BCL3; ZNF415; EED; TRIM25; AHR; SUPT7L; RBL2; GATA2; DRAP1; EZH2; ZNF264; TRIM29; DR1; RFXANK; ZSCAN32; CDIP1; ID2; MED17; ZNF217; MED20; IRF3; ZNF468; ZNF576; ZBTB43; CREB3; PCGF1; EPAS1; SPI1; EGR4; ZNF202; VPS72; NFATC4; DLX2; RUVBL1; PSMC3IP; FOS; NR4A3; RHOA; SSX1; CCNT1; IRF4; NFE2L3; AIP; MSC; IRF9; RNF6; LMCD1; RUNX3; MYBL2; ERF; ZNF331; WT1; ZNF267; KLF13; KLF9; CDYL; OSR2; JUNB; ILF2; NR1D2; CCNH; NFAT5; LOXL2; SOX9; DDIT3; ZNF232; SPIB; NR1H3; SSBP2; CEBPD; SERTAD2; YAP1; TDP2; ZNF44; RB1; HOXD3; PSMC3; SMARCA2; NKX3-1; TXNIP; TRIM16; KLF10; MITF; MYCBP; ELF3; SCAND1; CCNE1; RARA; FLNA; MYBL1; NFE2; MAF; NFATC3; SAP30; BHLHE40; ZNF652; NR4A1; TWIST1; CITED2; RUNX1; LITAF; TSC22D1; JUND; NCOA3; HIF1A; ATF5
Down-regulation	210	USP22; SOX4; HDAC2; KAT6A; SMARCA4; ZMIZ1; SALL1; SREBF2; PUF60; MTA1; SND1; SMAD4; CUX1; NFE2L1; MAGED1; TCF4; RBBP4; ZSCAN18; BCLAF1; PMF1; TRRAP; PHF2; PARP1; PATZ1; ZNF146; MED24; CBX5; CARM1; SMARCC1; ZMYND8; ID4; BACH2; BAZ1B; PGR; PBRM1; MAZ; RBBP7; SFPQ; HNRNPD; USF2; GTF2IRD1; TLE1; TCF12; BRD3; RREB1; SF1; CBFB; CDK7; ZFHX3; THRA; TCF20; KDM5A; NR3C2; HMGB1; FOXK2; BPTF; ZNF274; TBL1XR1; PRKDC; CREB5; POU2F1; TAF10; HDGF; SPEN; TLE4; GLI3; E2F5; ZNF536; VGLL4; HDAC6; BBX; MEOX2; CCNC; MYT1L; HEY2; PRMT2; TRIM28; SMARCC2; SSBP3; SOX17; RNF10; ZNF292; PSIP1; ZNF532; ERBB2; SOX11; ARID1A; RERE; CLOCK; SMAD2; IKBKAP; NCOR2; BAZ2B; HOXB7; MSX1; ATN1; HMGXB4; NR2F1; CITED1; STAT6; PLAGL1; MED23; EMX2; UBTF; SP3; USP21; VEZF1; CHD7; KAT7; ZIC3; HDAC1; ETS1; URI1; HOXD10; NR2F2; RBM14; DEAF1; CENPF; HMGA1; POU4F1; HOXB13; PA2G4; SMARCE1; HOXC4; REPIN1; TULP4; JARID2; XRCC6; TERF2; GRHL2; GTF3A; CNOT2; KAT6B; SOX2; WNT4; IRF8; PCGF2; RAN; NCOR1; INSM1; TCEA1; SMARCA1; TCERG1; HDAC4; CAMTA1; CBX3; INSR; TBL1X; SMARCA5; RBBP8; CHD1; FOXN3; KLF7; LEF1; MXI1; PHF8; SIAH2; ARID4B; CTNNB1; PBXIP1; RBPJ; CSDE1; SMAD1; HEY1; ZBED1; TOX3; C1QBP; POU2AF1; HIRA; MDM4; TRAK1; SMARCB1; TOX; YWHAB; CTBP2; NCOA1; FOXG1; KLF6; FHL2; APEX1; ZNF423; CNOT6; HOXB2; ECD; ZHX2; ASCL1; HMG20B; BRD4; MYCN; TCF7L1; NRIP1; ZIC1; ID3; EYA1; NANOG; AFF1; EYA2; ZMYM2; KDM5D; HMGB2; SUB1; ID1; CREB1; ZEB1; PRRX1; BTG1; ETS2; BASP1; HOXA5; ESR1