Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58854	Canertinib	GSE92742	HA1E	Human	6h	10uM	EID0329

Response Information :

Types	Number	Response transcription factors
Up-regulation	175	GATA3; SSBP2; OSR2; KAT6B; CREG1; SPDEF; DMTF1; ZNF14; AIP; ZNF394; ZNF415; ZIM2; ZNF273; HOXD3; SMARCD3; HESX1; HTATIP2; ZNF701; FOXO4; ZNF33B; HDAC5; HMGN3; SSX1; TLX3; ZNF263; CDK7; TOB1; NKX3-2; ZNF180; PAWR; ZNF226; CBX7; BLZF1; NFRKB; HSF2; URI1; CEBPB; THRA; TFAP2C; EZH2; ZNF44; PBXIP1; BRPF1; WNT4; TEAD3; TRPS1; WT1; PITX2; GBX1; MYRF; CRTC1; PHF20; KMT2A; CENPF; CCDC59; CSDC2; SERTAD2; NFIL3; MED21; TRIM32; ZNF350; TCF21; HDAC6; ZKSCAN1; GRHL2; SNAI2; MYCN; ESR1; ZNF43; HMGXB4; PEG3; FOXA1; GATA6; PLAGL1; THAP10; CERS6; FOXF2; TWIST1; ZNF611; ZNF430; RBBP5; ZNF667; OLIG2; HBP1; SIRT2; ZNF3; SNIP1; IKBKAP; UBE2B; PFDN5; RARG; ING2; MEIS1; IRF4; MEIS2; ITGB3BP; ZNF83; HCFC2; ZNF468; ZNF136; ZNF529; LITAF; MXI1; BCL6; CEBPA; TCF7L2; CIR1; COPS2; CD3D; RORA; HOXD1; TSC22D3; TOX; ELF2; ZIC1; RHOA; RSF1; EYA2; SAP30; TAF5; HMGB2; MAF; BACH2; FOXO1; RBPMS; CNOT2; CERS4; EN1; PIR; ZNF329; CREM; ZNF432; E2F8; KAT2B; RXRA; ZFPM2; SOX17; ARID4B; ZNF665; ZNF721; EGR3; TRIB3; SSBP3; TCEB2; ZNF160; YWHAB; TSC22D1; NKX2-2; JUP; RBL2; RBPJ; NCOA2; ZFP36L2; IL16; MNDA; RUNX3; FOXF1; SLC2A4RG; AHR; ID2; HHEX; ZNF551; CUX1; HOXB2; TCF7; TBL1X; ZHX2; BHLHE41; MTA1; CRYM; KDM5D; ZNF91; SOX11; ZNF586; STAT5B
Down-regulation	155	JUN; HMGA2; SMARCA4; BAZ1A; TRIM27; HMGA1; NFATC4; SMAD3; MYC; ID3; YY1; ZBTB38; ETS2; IRF5; NFKB2; PRKDC; FOSB; PREB; SUPT6H; TRIM29; TGFB1; GCFC2; ZSCAN9; LOXL2; NFYC; MGA; BRD3; SPI1; TFEB; KDM5B; TGIF2; INSM1; HOXD9; ORC2; CDK8; FOSL2; MSC; LYL1; MED12; ATF1; POU3F2; JARID2; HEY1; FUBP1; CREB1; NR2F2; DEK; SUPT4H1; TSC22D2; PDLIM1; FOSL1; BRCA2; POU5F1B; AFF1; PBX2; SFPQ; TRIP11; HOXC10; BRCA1; SREBF2; KLF10; ERF; NRIP1; XRCC6; BASP1; CLOCK; MED16; DLX2; RCOR3; LZTS1; ZMYM2; RELB; BATF3; MAGED1; MEF2C; SUPT7L; CIITA; KAT8; SMAD1; HOXD11; HIVEP1; ID1; ATF7IP; RFX5; SFMBT1; NR1I2; PPARGC1A; CHD7; CBFB; STAT6; MYCBP; ELK3; SF1; ARL2BP; CTBP1; NPAT; ERG; HNRNPD; HDAC4; SPEN; MSX1; SOX9; HMGB1; KLF11; FLNA; ING3; MED13; NFE2L1; REL; CREB5; PMS1; TCF7L1; CDK9; TAF1D; NFKBIA; RNF14; TLE2; BAZ2A; TFDP2; ZBTB18; ZFHX4; CNBP; YBX3; GATAD2A; UBE2L3; KLF5; ATF3; NR4A1; PURA; NKX2-1; BAZ2B; TGFB1I1; SRCAP; KLF7; CRY1; TAL1; REPIN1; SATB2; RB1; ZZZ3; ZEB1; KLF6; ZNF281; FOS; ZNF593; BIRC2; ARID5B; PBX3; DACH1; TXNIP; ISL1; IRF8; CTBP2; NFATC3; TOX3