Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID58611 Torin-2 GSE92742 HA1E Human 6h 10uM EID0328
Types Number Response transcription factors
Up-regulation 100 MYC; SOX4; ATF4; STAT2; DDIT3; BCOR; NPAS2; GON4L; HBP1; EZH2; SETDB1; PPARD; BRD8; CALCOCO1; MNT; TCERG1; BLZF1; BAZ2B; ZKSCAN1; SSBP3; CDK7; ZNF432; CEBPB; CAMTA2; PAWR; KDM5B; HOXD1; RBPJ; ZNF195; PBXIP1; HINFP; HMGA1; ZNF573; ERBB4; DMTF1; ZNF84; ZNF611; ZNF587; NFE2L3; ZZZ3; TMF1; ZNF202; ZNF140; RAD21; KLF7; ASCL1; KLF5; ZNF354A; CTBP2; SRCAP; SP100; TERF1; ZBTB11; JUND; ETV4; KDM5D; RB1; TOX; PLAGL1; XBP1; BMI1; NFX1; TLE4; IRF1; ARNTL2; TLE1; STAT6; TOX3; MAZ; ZNF160; ZNF83; FLI1; HMGA2; ELF4; SIRT7; ELF3; HDAC6; PSPC1; AFF1; STAT4; CARHSP1; UBE2B; BTG1; EGR3; SATB2; CRYM; ARID4B; MAFB; NR1D2; FOXC1; HTATIP2; INSR; NRIP1; POU2AF1; TDP2; HDAC9; MTA1; NR1H2; TFAP2A; IKZF1
Down-regulation 81 MAGED1; RNF4; RFXANK; SFPQ; NR2F6; HMGN3; PARP1; PSMC3; PIR; NFKBIA; JUN; SMARCD2; MYT1; THAP11; ZSCAN5A; ID1; TOX4; ILF2; ZBTB16; PSMD9; DR1; TLE2; ID3; SIAH2; TRIM27; ENO1; E2F6; SCAND1; NOC2L; SIX3; GATAD2A; NR4A2; ADNP2; PDLIM1; SRF; CLOCK; SALL2; TFDP1; ATF6; MTDH; FOXJ2; ZBTB18; HEY1; MXD4; SERTAD2; SAP18; EGR2; ZNF148; RBBP7; DAXX; NFATC3; HHEX; CITED1; SP3; POLR2A; ZNF331; ZFHX4; CERS4; RNF6; ZNF652; ESR1; PCGF2; LMCD1; TCF4; BIRC2; ZNF512B; TRIM32; MSX1; ATF5; MKL2; ETS2; EYA2; MEIS2; FOXF1; MNAT1; ID2; SMAD1; ZIC1; HOXC6; LEF1; ZNF589