Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58578	Aprepitant	GSE92742	HA1E	Human	6h	10uM	EID0327

Response Information :

Types	Number	Response transcription factors
Up-regulation	357	NFKB2; TBX2; SSBP2; MDM2; NFATC3; SOX10; PPARD; CREM; ZNF415; ZNF286A; NCOA3; IRF4; MYCN; ERBB4; ZNF701; E2F2; ZNF492; ZNF117; PRDM14; MNX1; SOHLH2; CEBPZ; ZNF257; ID4; SOX2; LIN28A; ZNF208; PEG3; IKZF2; TRPS1; ZNF331; HOXC10; VGLL1; ZNF552; HHEX; ZNF165; NKRF; HIC2; ZIM2; ZBTB44; SOX5; HMGA2; NEUROD1; NANOG; JUP; ZFP2; TXNIP; ZNF460; ZBTB39; ZIC3; RARG; SP4; EYA3; ACTL6B; TFDP2; EN2; SSX7; FOXF2; TBX5; FOXE1; ZKSCAN4; ZNF711; ZNF695; POU2F3; IL16; SSX1; CREB3L2; EGR1; ZFY; SMARCD1; THAP7; RNF141; STAT4; PRDM5; ZBED2; NR1H4; ZNF337; POU2AF1; DNMT3B; MYT1L; TGIF1; TRIM24; POU4F2; ZNF506; CLOCK; SOX4; ZFP30; E2F3; ZNF239; KDM5B; YBX2; ZNF391; ZNF571; ZNF214; OVOL2; ZNF141; NFAT5; NFE2L2; CHD2; CBX5; MECP2; ZNF157; POU4F1; NR2F6; ZNF816; HOXC11; POU6F1; PHIP; KLF8; TAF4B; NR0B1; EHMT2; LZTR1; NFKB1; DMRT1; KLF3; ZNF682; ZNF273; CCNE1; ELF3; FOXH1; SSX3; WHSC1L1; PRDM1; ZSCAN18; BBX; ARID3A; NKX2-2; ZNF574; TULP2; VAX2; TFAP2C; OLIG2; BRDT; PPARG; MYRF; HR; ZNF43; HNF1B; HOXA2; BARX1; POU5F1B; ZNF131; RING1; NOCT; ZIC1; MNDA; FOXF1; DLX5; MYT1; PHF1; POU2F1; GCM1; ZNF254; ZNF253; LIMD1; SOX30; CAMTA1; HDAC9; ZNF442; ZXDC; BHLHE41; OSR2; STAT5A; HOXA1; TSC22D3; TRIM29; ZNF329; ZNF287; ZNF202; ZNF778; SIAH2; SMARCA1; TBL1X; ZKSCAN8; ZNF512B; PKNOX2; DAXX; KAT7; HOXC4; EPAS1; AFF4; SALL2; GRHL2; CHD7; TRIM28; RFX2; ZNF124; LZTS1; SMARCD3; TERF1; TFDP3; MEOX2; TGS1; NCOA2; KDM5D; RSF1; SFMBT1; FOXG1; FEV; ZNF85; PLAGL1; ZEB2; ZNF423; ZNF184; HMGN3; ZNF354A; URI1; MEN1; TCEA2; MYBL1; XBP1; EGR4; EN1; TAF12; AHR; KAT6B; THAP11; CBFA2T3; NR2C2; CIITA; NKX2-1; ZNF135; ZNF14; SP140; RBPMS; RUNX3; ARL2BP; ZBTB3; PRDM2; ZNF671; SPDEF; NAB2; BCL11A; TAF1; RXRB; E2F6; NR4A2; CARHSP1; EZH1; ISL1; ZNF334; TULP4; BNC2; NKX3-2; ADNP2; BTG1; TOX; ZNF835; ZNF324; MXD1; MYCBP; ZFP64; ZNF654; ARID3B; HMBOX1; TAF1D; STAT5B; ECD; E2F5; HDAC6; PBX1; IRX5; MGA; HMGXB4; ARRB1; NHLH2; ZNF215; CHD1; TRIM33; BATF; HOXD3; SKI; ZFPM2; TBX21; ZNF33B; CTNNB1; ZHX3; ING2; TFAP2A; ING1; PAX8; DPF2; HSBP1; ZNF467; CHD9; HMGA1; PFDN5; SUPT6H; ABT1; WT1; ZNF443; SIM1; ST18; ZNF148; CCNT1; BACH1; CHD3; RNF10; FLI1; KMT2A; VPS72; SMAD2; KLF11; FOXC1; NCOA1; AGO2; TWIST1; TCF21; NR1D2; ZFP36L2; PA2G4; SIX3; IKZF5; JUN; WWC1; LDB1; REL; POLR2A; SP3; DDIT3; ETV5; HLF; SIM2; CDYL; ZHX2; NRIP1; GTF2I; NPAS2; NR2C1; ZBTB20; PRMT2; STAT2; HOXC6; MYB; AFF1; CALCOCO1; TRIB3; FOXJ1; AEBP1; MAGED1; HIVEP2; TP63; IRF6; SOX11; PAX5; IRF9; PITX1; PHOX2B; SERTAD2; CRYM; ZNF532; ARNT2; ZNF304; PIR; TGFB1; PBX3
Down-regulation	405	PSIP1; BASP1; SCAND1; ABL1; GATA6; FOXM1; VGLL4; NCOR2; PSPC1; BRF2; MED17; ZEB1; LOXL2; BRD3; BRCA1; SAFB2; ZNF140; MED21; HMGB1; MED13; CENPF; CREBL2; MED23; XRCC6; ERF; MED24; ENO1; ZNF358; ID3; CDK8; PDLIM1; ERCC2; TBP; RBBP5; IRF3; RHOA; RBM14; FLNA; TSC22D2; ZNF227; SAP18; NKX2-8; ZNF516; ZMIZ1; WHSC1; ETV6; ZMYM2; MAX; HDAC2; HEYL; ANKRD1; RCOR3; CREB3L1; ZNF143; APEX1; HMGXB3; MED27; NR2F2; CBFB; BRD8; NPAS1; KLF4; RNF6; DACH1; TCF3; IRF2; KLF7; IKZF4; MAZ; NR1I2; ATF2; WDR77; PHF2; UBE2L3; CEBPG; THAP10; HOXB13; TBX10; NONO; BAZ1A; KMT2D; BRD4; MED6; RORC; ZFX; MED15; ZBTB18; HOXA7; SPI1; ZNF410; ZKSCAN1; C1D; CDX2; MBD3; ZBED4; PLAGL2; ZNF576; RAN; SIX5; CEBPE; HSF2; BAZ2B; ZNF23; VSX1; ARID4B; ESRRB; SMAD3; ZNF177; SPEN; ZNF302; ASH2L; NFIC; ID2; SMAD4; NFIB; ZBTB7A; PMF1; SP110; ARID5B; TMF1; COPS5; HOXA4; ZNF672; NELFB; MTF2; GTF2F1; TLX2; TCERG1; SETD3; YAP1; ZNF32; SP2; HABP4; USP22; HOXD9; FOXO3; CBX4; NUP62; DR1; ZSCAN2; CNOT3; ZNF189; SOX9; LEF1; NCOA4; BIRC2; RAX; RXRA; CERS4; IRF7; DEK; SMAD7; ZNF226; ZNF197; MED31; ZNF224; CTR9; GCFC2; CTBP1; PRKDC; DDX5; LBX1; LMX1B; MSX1; MAFG; PEX2; NRF1; SF1; ATF3; ZNF84; TSHZ2; PPARGC1A; REST; NKX3-1; TCF25; CRY1; HINFP; APBB1; GLI2; SAFB; ZNF12; HOXA6; HLX; CIZ1; EMX2; TCF7L2; MAPK8IP1; ZNF771; MED16; FHL2; ZNF146; HOXD11; E2F1; DDX17; PITX3; ZNF710; RFX5; CCDC59; MBD2; REXO4; NFX1; NCOR1; TRIP4; SSRP1; ZNF212; IFI16; MYF6; ATF4; FOXL2; HIRA; HOXB9; BCL6; TBX1; NFYC; RAD21; RBM39; TBX3; ZFHX2; HOXD10; NFE2L1; TTF2; TAF4; TOB1; POLR3F; KLF15; ZNF45; ATF1; SP100; GMEB2; PREB; POU4F3; CCNA2; ARNTL; TULP3; ZNF250; C1QBP; TGFB1I1; MLXIPL; RFXANK; HDAC5; CSDC2; TAF10; BATF3; SMARCB1; EVX1; PHF8; YBX3; PPP1R13L; MAF; ZBTB17; CHD8; ZNF292; HIPK1; MAFF; HCFC2; ELK1; NR3C2; TAF11; NKX2-5; ZNF112; EED; DLX2; PTRF; LHX2; BAZ1B; SATB2; WWTR1; SIX2; KDM2A; TOX3; TSG101; MSC; FOXI1; FOSL1; ZNF232; ZNF593; ATF5; BCOR; BTAF1; PSMC3; BLZF1; TDP2; BRCA2; SMARCA2; TFEB; HMGB3; PTTG1; PCGF1; INSR; HBP1; ZNF91; PCGF3; TCF7; KMT5A; SIRT7; ZNF787; PAWR; PMS1; TTF1; ZSCAN16; ZNF562; MMS19; CRK; MEF2A; CREB1; DEAF1; FOXN3; YEATS2; AIP; PBXIP1; CAMTA2; ACTL6A; GATAD2A; FOXO1; ENY2; MAML1; ZBTB11; ZNF281; PSMC3IP; STAT6; CSDE1; ADNP; ZBTB43; HSF4; UBE3A; VDR; ZNF222; SRF; MEIS2; IRX4; ASXL1; TAF6; PROX1; MNAT1; HOXA5; CEBPD; ZBED1; CIC; SUPT3H; SMAD6; MAK; TEAD4; DNAJC1; MLX; GTF2IRD1; LPIN2; NR1H2; KLF5; ILF2; ZNF432; CDX1; ZNF7; MTA2; RBBP4; HSF1; MTA1; SMAD1; PGR; NR4A1; CITED1; ZNF211; MED1; BCL3; MITF; SUB1; INSM1; ETS2; ZNF274; JUND; FOXA1; JUNB; RUNX1; HIVEP1; CITED2; ZBTB16; VEZF1; CALR; TLE4; HOXB6; MEOX1; SMARCE1; EYA2; ZMYND8; ERG; SOX17; CEBPB; HDAC1; SALL1; MEIS1; FOS; ID1; MYCL; NFATC1; FOSB; PCGF2; CTBP2; NFE2L3; ZNF551; ZFP36L1; NR2F1; ZNF544; TFEC; MAFB; IKZF1; ZNF586