Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58324	Pf-562271	GSE92742	ASC	Human	24h	10uM	EID0326

Response Information :

Types	Number	Response transcription factors
Up-regulation	177	MEIS2; CREB1; NFATC3; SCAI; NR1H2; ZNF440; ERBB4; ZNF264; WT1; MYBL2; CDIP1; SOX2; ZNF345; ZNF117; ZIC3; ZNF816; TTF2; ZNF224; ZNF586; MXI1; ZNF75D; LIN28A; HESX1; SIX3; ZNF551; ZNF675; VENTX; KLF7; SOX3; ZNF273; ZNF136; YEATS4; INSM1; ZNF611; EMX2; PRDM12; DLX5; VPS72; ETS1; ATN1; TFAP2A; HOXA2; ZBED2; ZNF131; MED14; CREB5; WNT4; PAWR; TAF9B; HIPK2; FEZF2; ZNF528; ZFPM2; NHLH2; RARG; ST18; RBFOX2; ZNF682; ZNF529; ARNT2; HOXB5; ZNF141; ZNF665; YAP1; ZNF415; GTF2I; HAND1; TCF4; NFE2L2; MBD4; ZNF331; L3MBTL1; PAX6; NFE2L3; ZNF83; CREB3L2; ID3; FOXM1; NR5A2; CARHSP1; BCL11A; SKIL; FOS; TCF21; ZNF268; ZNF562; PCGF3; PBX3; SOX17; CERS6; SUPT3H; ZNF43; SIX6; HBP1; MYCBP; FOXG1; GATA6; E2F5; ZNF140; SNAI2; FOXN3; RBBP8; ZFHX4; REL; ZNF423; ZNF711; ATF3; NFATC4; NEUROD1; TWIST1; SUMO1; ZNF532; ID4; ZNF623; TCEB2; AEBP1; NR4A3; ZNF492; CREM; MYCN; CSDE1; PBX1; SOX11; ZNF107; VGLL1; WWC1; C1QBP; KLF13; TULP3; MNDA; URI1; NR4A2; DLX2; PSMC3; ZNF467; MEOX2; HOXB6; MDM2; CNBP; HOXA1; HOXD1; ZNF468; EHF; ZNF124; EPAS1; IFI16; LEF1; HEY1; TRIB3; ZNF232; BNC2; MYT1L; ZNF304; BACH2; SSX1; SHOX2; NANOG; MYBL1; HDAC9; TGFB1; ZNF91; MEIS1; MKL2; NFKB2; HOXB2; ZNF652; ESR1; TOX; TRPS1; ZEB1; TCEA2; CUX2; HHEX; DACH1; EGR1; SPDEF; ID1
Down-regulation	334	CEBPA; NRIP1; PUF60; MYC; XBP1; FOSL1; USP22; SCAND1; RBM14; SNW1; PATZ1; KAT5; VGLL4; TP53; ZMIZ2; REPIN1; AATF; CNOT1; TLE1; TRIM27; ZNF629; SFPQ; TRIP11; PAX8; BRD3; ZNF282; SOX4; SUV39H1; KAT7; DDIT3; SMARCD1; CEBPZ; RNF4; HDAC2; UBE2I; STAT5A; TBP; TRIM16; ADNP; ABL1; BCLAF1; BRD2; TSC22D4; TSG101; RARA; BRPF1; SMARCE1; NFKB1; RXRB; BCL3; UBP1; ASH2L; SMAD7; NCOA4; TRIM32; NFKBIB; ZNF574; PHF20; ARID4B; CRYM; DNAJC2; ZNF189; BRD8; ZBTB11; RELB; DDX54; CTR9; BAZ1B; GMEB2; STAT5B; PIAS2; RAN; SMAD3; ELF1; ZBTB7A; BHLHE40; MLX; SMARCC1; NUP62; TRIM28; RNF111; BRF2; MED1; MGA; KDM4A; RREB1; SAFB; CDYL; ORC2; CENPB; ATF6; CCNA2; SIRT7; PIR; TRIP4; ING2; ZNF263; PHF8; HOXA10; RELA; TGS1; BRCA1; MNAT1; HOXA11; RBBP4; ZFP64; DPF2; ID2; POLR2A; USF2; NR3C1; SIX1; ZNF45; MED23; DDX5; PPRC1; JARID2; BATF3; TERF2; ELK1; YAF2; ZSCAN5A; PA2G4; ZNF384; LPIN2; SNIP1; CREB3L1; TAF1D; ZNF226; RUVBL2; GTF2IRD1; TSC22D1; TBPL1; FOXO3; ZNF410; YEATS2; FOSL2; SIRT2; NPAT; NELFB; PTTG1; MED27; HNRNPD; HMGXB4; CENPF; ZNF239; ZNF281; ERCC3; TFE3; MED20; BAZ1A; ZNF143; KDM4C; PSPC1; HDAC1; COPS5; CXXC1; CASZ1; RNF141; BASP1; SMAD2; BLM; IRF2; KDM2A; DDX17; HDAC7; NCOA6; KAT6A; HR; HMGB2; SAFB2; ZNF408; ARID4A; NR1H3; KAT8; MLXIPL; SIAH2; BATF; HMG20A; EWSR1; PLAGL2; UIMC1; FOXA1; MEN1; CTCF; ZBTB40; CEBPB; BANP; TAF10; NFYC; TCF25; ARID5A; RCOR1; CBFB; TFCP2; CARM1; HDGF; ZNF337; HOXC6; VEZF1; RUNX1; TMF1; SREBF1; HSBP1; EED; TRAK1; LYL1; ZNF576; SMARCA2; ELK3; ZSCAN16; DNAJC1; TGFB1I1; CTNNB1; TBX3; KLF2; SF1; THAP11; ETS2; ZNF580; RBM39; SMARCD2; ZZZ3; NRBF2; ZNF443; NEDD8; SAP30; TCF12; CHD1; SOX10; TAF4; STAT3; ERG; ZMYM2; ZNF672; SAP18; IKBKAP; NKX3-1; TGIF1; AFF1; ING3; TRIP6; ASXL1; POU3F1; TFEB; STAT6; DEK; TBX2; SMAD1; TRIM22; PRRX2; MSC; TRIM24; NFX1; USP21; ELF4; CCDC59; PCGF2; PMS1; NPAS2; ELF3; ZNF7; HOXC10; EZH2; ATF4; MNT; RBBP7; SALL1; KDM5D; DEAF1; HTATIP2; LOXL2; SATB2; EYA2; FOXO1; JUNB; MAFF; MBD2; KDM5A; SIX2; MED6; RLF; NCOR2; APEX1; STAT1; IRF7; RNF138; ZBED1; ZBTB18; TBL1XR1; FOXJ3; DNMT3B; ERBB2; XRCC6; SMARCD3; OSR2; ZNF266; RBPJ; ZEB2; PQBP1; MAGED1; MEF2A; KAT6B; IRF1; BMI1; CBX3; MLXIP; ECD; POU4F1; OLIG2; SSBP2; ZNF516; NAB1; MAF; POU2AF1; SMARCA1; YWHAB; SIM2; CEBPD; PURA; TOB1; CRK; HMGA2; FHL2; HDAC6; PAX5; JUP; ELF5; RBPMS; ZIC1; TOX3; ZBTB16; ZNF217; ATF5