Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58263	Hydroxycholesterol	GSE92742	ASC	Human	24h	10uM	EID0325

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	EGR1; NKX2-1; JUN; GATA6; HES1; DLX5; BAZ2A; ZNF74; ZSCAN9; TULP3; SOX18; CHD4; OVOL2; TBX3; ZKSCAN4; ATF3; ZNF232; AES; SKI; ZNF711; HOXD13; ZBED2; HIC2; FOXG1; CRYM; TP73; ZNF492; ATOH1; ZNF623; ZNF331; BNC1; PROX1; ZFHX3; CCNH; HIRA; MKL2; TCF20; GTF2F1; PFDN5; ZNF165; GRHL2; ST18; ENY2; HDAC4; E2F3; GMNN; MXI1; TRIB3; CHD8; ZNF124; TBX1; PIAS4; MEIS2; NR4A1; TCF7L2; ARID5B; SOX3; SOHLH2; MTF2; PBXIP1; HMGB1; MITF; ZNF682; CBX7; VGLL1; FOXE1; IRF6; CDK2; CNOT3; ZNF215; ERBB4; SOX17; PSMC3; NR4A2; DLX2; SAP130; MLXIP; ISL1; INSR; CD3D; ID4; MNDA; DNMT1; JUNB; EGR3; TFAP2A; TXNIP; PIAS1; SOX13; MYCL; PHIP; MYBL2; ID1; NKX2-2; MYCN; INSM1; MAFB; PBX3; EGR4; OSR2; SATB2; MYRF; ZNF117; ZNF83; PGR; TRPS1; HAND1; ZMIZ1; TOX; SSBP2; ID3; TWIST1; DACH1; HMGN3; POU2AF1; SOX9
Down-regulation	129	TLE4; CNOT2; HCFC2; ERBB2; STAT3; SREBF1; ELK1; TSC22D3; IRF8; BATF3; SMAD2; BCL6; RNF4; PCBD1; BCL3; ZBTB11; RB1; HLTF; BPTF; CDYL; HDAC6; CITED2; MTDH; HABP4; ZNF134; PPARG; TRIP6; NFKB1; TRIP4; ZNF146; TSG101; STAT5A; PCGF2; ZNF226; SETD2; CRK; HMG20A; SMAD4; SETD3; BMI1; ATF4; ATF2; RBBP4; ZNF84; CBX3; C1D; MTA1; KDM5D; TBL1X; SUV39H1; CTR9; REST; TRAK1; FOXJ3; NFYC; LITAF; ZNF217; ZNF131; ASH2L; UBP1; EDF1; IRX5; RNF10; RBPMS; TRIM22; CASZ1; IKBKAP; XBP1; NUP62; RBM14; HTATIP2; YWHAB; WWTR1; ENO1; POU5F1B; ING2; MSX1; SP100; MYCBP; ZEB1; NRIP1; C1QBP; EMX2; PBX1; SMARCA1; ZMYM2; BASP1; ZZZ3; RBBP8; KLF7; CCNA2; MEIS1; ZIC1; CDK9; SPEN; ZBTB38; NFIL3; CREG1; ZNF329; SOX10; BCLAF1; SIX1; HOXD1; RUNX1; HIVEP2; EZH2; CHD9; HOXB2; LMCD1; NCOA4; PSIP1; KAT6B; TSC22D2; SIAH2; HOXB7; PEG3; RBPJ; HIPK3; FOXO1; SMAD3; HOXC6; ZNF589; NR2F1; HOXB6; MAF; TLE1; MECOM; ECD; NFKB2