Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58211	Celastrol	GSE92742	ASC	Human	24h	10uM	EID0325

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	FOXO4; TCF15; HMX1; MYOG; ZNF646; MTA1; ZNF787; SIX5; HSF1; E2F4; SIRT2; ETV7; MNX1; TONSL; TP53; ATOH1; EYA1; ZNF205; SIRT7; BARX1; ERCC2; CBFA2T2; APBB1; CDX2; ZBTB7A; TRPS1; DLX5; SPI1; MXI1; GTF2F1; DNAJC1; ZNF500; MEF2D; TAF5; RING1; PHF1; ETV2; SSX3; RXRB; HAND2; TCF20; AGO2; SIX2; CALR; RBM39; MLXIPL; CNOT3; ZNF331; CBX4; PEG3; CEBPE; ZFP36L2; BAZ2A; PFDN5; FOXK2; SSX1; DBP; BRD2; ZNF224; ZBED2; KLF5; RFXANK; ARHGAP35; HDAC7; MYCN; PBX2; SATB2; TSC22D4; NAB2; EVX1; MAZ; HDAC4; PNRC1; KDM4C; DNMT1; ID1; SMARCB1; MSC; SMAD6; WT1; RBFOX2; ALX1; HMGA1; EN1; IRF6; NR0B1; PITX1; MYRF; FOXG1; SSBP3; CD3D; SSBP2; HEY1; MAF; ST18; NR1H2; TCF21; SNAI2; NKX2-2; ZNF281; EHF; TOX; ZIC1; ID4; CITED1; FOXL2; MECOM; SOX9; DACH1
Down-regulation	100	TSC22D3; STAT3; RBPMS; RNF4; C1D; RRN3; CBX3; REST; ZBED1; MTDH; ZNF107; SMARCE1; ZNF140; ERBB2; ZBTB11; LEF1; ZKSCAN7; RB1; FOXJ3; MED4; NELFB; TRIM22; EMX2; EDF1; ZBTB24; HDAC6; BCL6; PPARG; PCGF2; ETS2; ZBTB20; SP2; IRF8; KLF6; SMAD2; EGR2; ESR1; CCDC59; ELK3; STAT6; YWHAB; SMARCA5; XBP1; TLE1; SOX4; IKBKAP; TRIP6; ZNF443; IRX5; EGR3; TBL1X; MYCBP; GTF2I; NRBF2; CHD9; TSC22D2; FOSL2; RFX5; ZMYM2; KDM5D; CTBP1; CUX1; CRK; RNF6; ZNF117; PHF20; ZZZ3; HOXA10; HNRNPD; PTRF; CREB5; KLF10; SAP30; PLAGL1; SFPQ; ZSCAN18; ZFP36L1; CCNC; HOXA5; NCOA4; FOXN3; REL; TCF7L1; ZNF432; KAT6B; HOXA11; BNC2; ID2; ZBTB18; HIPK3; AEBP1; WWTR1; SERTAD2; PSIP1; HMGB2; BAZ1A; HMGN3; BASP1; ECD; NFKB2