Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58190	Plx-4720	GSE92742	ASC	Human	24h	10uM	EID0325

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	NFATC3; DLX2; NKX2-1; JUP; ADRB2; NFKBIB; AES; NFIC; SSX1; HSBP1; TFCP2; POU2F2; WT1; DLX5; SPIB; ATF1; MGA; MNX1; HMGA2; PFDN5; TXNIP; NR4A2; NRIP1; NFAT5; NR4A1; ST18; PROX1; SIRT2; JARID2; AIP; NOC2L; SIRT7; PIAS4; GTF2F1; MTF2; ZNF646; GATAD2A; RCOR1; ZNF124; FLI1; ZNF212; HHEX; ABT1; BHLHE40; ZBTB39; HR; MEF2D; SMARCD1; APEX1; PARP1; BATF; PSMC3; MEF2C; ZMYND11; NAB2; THAP4; JUNB; KLF13; EDF1; FOXE1; EP300; CARHSP1; LITAF; KAT7; ZNF205; CDK2; E4F1; CHD4; LHX6; NR4A3; EVX1; PHF1; KAT5; FEV; RFX5; HBP1; NFYC; MYCN; IRF6; ZBTB43; PAX5; VDR; ZNF331; HMGB3; MAZ; HOXC4; ZNF384; FOXL2; SSBP2; NONO; NR1D2; MAFB; MLXIP; MED17; MEOX1; PRDM1; NFKB1; MLX; CD3D; BTF3; KAT6B; NR0B1; RHOA; SSBP3; BACH1; FOXF1; RBBP8; IRF9; HDAC4; PGR; TCEB2; NR2F2; OSR2; NFKB2; BACH2; PSMC3IP; TCF21; GATA4; ETV5; ZMIZ1; ZBTB16; TOX; AR; BRCA1; HOXC6; NR1H2; ZNF589; HEY1; CREB3L2; SIAH2; SOX9; HMG20B; HOXC10; ID4
Down-regulation	129	KLF6; CRK; MTDH; BMI1; RB1; HCFC2; TBL1X; SREBF1; CLOCK; FOXJ3; MMS19; ZNF529; ATF4; TRIP6; HOXA5; RNF6; E2F3; ZNF24; HMG20A; REPIN1; PIR; SMAD2; TSC22D3; ZBTB7A; SMAD3; ZMYM2; MYCBP; YWHAB; RNF14; SMARCA5; PIAS2; ATF2; RNF10; BTAF1; ZNF544; FOSB; MEOX2; RBBP5; C1D; NKX3-1; PSIP1; ELK3; CBX6; PPARG; TLE1; WWP1; TCF4; ID2; CCNH; PRKDC; CBX3; HOXA10; NRBF2; ZNF83; IKBKAP; ARNTL; GCFC2; MED20; ATF3; COPS5; ZEB1; CREBL2; HLTF; TRIM22; REST; BRD8; MED7; ZNF131; RUNX3; HDAC6; RNF138; ZNF302; MITF; NFIL3; IRF8; LPIN2; UBP1; NFYB; PURA; TRIM16; CREB3; MNT; PHF20; HIF1A; MYBL2; LOXL2; NCOA4; CREB1; ING2; ZNF532; NR2C1; ZNF432; IRX5; EYA2; ZBTB18; CCNC; RXRA; PBX3; BHLHE41; ZNF165; ZNF189; SUZ12; STAT1; FOXO1; ZZZ3; E2F5; NUP62; XBP1; KLF5; ID1; BAZ1A; TCERG1; CBFB; GTF3A; CEBPZ; POU2AF1; BASP1; SMAD7; EGR3; PAWR; TFEC; NR2F1; AEBP1; MECOM; ECD; USP22; NFATC4; EED; SMAD1