Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58173	Azd-6482	GSE92742	ASC	Human	24h	10uM	EID0325

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	DLX5; CDK2; TRPS1; INSR; VDR; HES1; NEUROD1; DLX2; ZNF415; RAD21; ERBB4; BHLHE41; MED21; ZNF536; PAX6; TULP3; LEF1; ZFP36L2; ZNF665; CDX1; TRIM22; TRIB3; TP63; ST18; SNAI2; SPDEF; HBP1; HOXD1; NKX2-1; KLF7; IRF6; ARNTL; ZNF91; NR2E1; MYCN; CD3D; MYBL2; ZNF354A; PNRC1; ZNF83; ZHX2; TOX; TFAP2C; TDP2; NR4A2; ZSCAN18; FOXG1; VPS72; TBX3; MYCL; IRF9; ATF3; TLE2; SATB2; NKX2-2; ID4; ZIC1; TOB1; INSM1; ZNF131; AHR; SOX9; SMAD7; TRIM29; GATA6; PAX5; HEY1; HDAC9; KLF5; MEIS1; ID1; TOX3; POU2AF1; PEG3
Down-regulation	66	ABL1; KAT6A; SMARCE1; FOXO3; RB1; TRIM16; NR2F2; NELFB; GABPB1; PCGF2; TLE4; TSG101; SIX2; PPRC1; RNF10; RNF4; CENPF; HTATIP2; TBPL1; RBPMS; SUV39H1; SOX4; MYCBP; PUF60; NFKB1; EDF1; RBM14; DNAJC1; TXNIP; EYA1; KLF1; KLF6; KDM5D; CTR9; TP53; SIAH2; FOSL1; SMARCA5; CCNA2; TRIM28; TBL1X; EZH2; MAGED1; PTRF; TCERG1; MED24; FLNA; SPEN; ING2; NCOA4; FOXD1; ENO1; ELF3; TSC22D1; PPARG; PIR; CEBPZ; TSC22D2; ZBTB38; TCEB2; BRCA1; XBP1; RBPJ; HOXC6; ECD; NFKB2