Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58150	Safinamide	GSE92742	ASC	Human	24h	10uM	EID0324

Response Information :

Types	Number	Response transcription factors
Up-regulation	207	BRPF1; GABPB1; MXD4; BRCA1; TSC22D2; NPAS2; ETV1; ELF3; SNIP1; TRRAP; BHLHE40; RARA; MEF2A; DRAP1; NAB1; SUB1; UBP1; KDM5D; SMAD7; PGR; HMG20B; BATF; TRIM29; ZNF83; ZNF516; ING3; YBX1; NFYC; PBX2; ZNF587; ELK3; KLF10; SUV39H1; EP300; THAP1; PRDM8; ADRB2; BATF3; CREB5; TRIM28; SMAD2; PLAGL1; TRIP6; NFATC1; RNF4; ZHX3; PLAG1; CTR9; ZNF329; NR2F2; KDM5A; POU4F1; HMGN3; NFIC; ZNF236; FHL5; ZNF764; JUP; HSF2; IRF4; SETD2; PARP1; ZNF134; ZBTB38; TRIM32; IFI16; RBPMS; YBX2; MED4; ESR1; XBP1; ZBTB24; NFATC4; TRIM33; ZNF282; SIAH2; RFX7; CHD1; FOSL1; LHX1; ZBTB16; MED21; FOXO4; SALL1; SATB1; ZNF783; HOXD10; JARID2; SMAD3; RLF; MAFF; IL16; ZNF274; CITED1; SOX15; HDAC1; VEZF1; RNF10; ITGB3BP; HOXA11; TBL1X; GTF3A; NHLH2; SMARCA4; BCOR; IRF2; BRD2; HCFC2; HLTF; THAP10; PHF8; ZNF468; BAZ1B; SSX1; NFKB1; CDK8; RNF14; HOXD11; DDX54; DNAJC2; HLF; EGR3; BAZ2B; TXNIP; IKBKAP; TADA3; TP53; ZNF226; PIAS2; EMX2; MSX1; ZNF217; BCL3; CUX1; IRX5; ARNTL; EDF1; ZIC1; FOXD1; RUNX3; ZBTB43; RBM14; ZNF266; DPF2; RORA; SNW1; SOX11; KAT6A; ZBED2; HTATIP2; MITF; TCF12; CREB3L2; ERBB2; DMTF1; HOXC6; PIAS3; NUP62; NFKBIA; TLE4; BBX; TCFL5; SMARCE1; PIR; NELFB; ASH2L; MED23; RHOA; TRAK1; TOB1; SCAND1; TRIM22; CCDC59; PBX1; MBD2; EGR1; SSBP2; TRPS1; NR0B1; MYCBP; PUF60; DACH1; JUND; RUVBL2; YWHAB; WWP1; TLE2; SOX17; ZEB2; INSM1; TAF10; ETS2; HOXC10; MED24; SMARCD2; KAT7; IRF1; FHL2; NRBF2; ZMYM2; STAT1; RBBP8; CRK; ERBB4; WT1; BASP1; CDK7
Down-regulation	177	ID3; HIRA; BIRC2; ARNT2; TFAP2A; ETS1; TGFB1; THAP7; MED15; UBE2L3; HSF1; SNAI2; MGA; CALR; TDP2; PBX3; SF1; TRIB3; FOXI1; ZNF74; ZNF264; ILF2; HIC2; YAP1; LOXL2; ZNF232; KDM5C; TCF3; ARID1A; SMARCB1; ARL2BP; EPAS1; VPS72; PHOX2B; TCEA1; CNOT3; ARRB1; NFYA; E2F8; CNBP; MED12; TFCP2; ZNF223; VDR; TCF7L2; PAXBP1; SETDB1; MYBL1; AEBP1; CEBPE; SUPT6H; MEIS2; ZBED1; PRRX1; ZNF124; FOXM1; HMGXB3; ZNF557; XRCC6; MAZ; CHD8; ZNF665; ZNF544; ATF4; COPS5; ZNF133; KMT2B; FOXF2; MDFI; ATN1; ZNF195; TERF2; USP16; ZNF141; ZNF573; ZNF32; ZFHX3; MLLT10; NFATC3; ZNF10; CCNH; CERS6; DNMT1; RXRA; SUPT5H; SPI1; PRKDC; DLX5; ZNF235; ZNF44; PEX14; TOX3; MYBL2; NR5A2; ZNF580; ZNF623; PSMC3; HIVEP1; CENPB; LZTR1; GMNN; SRCAP; TULP3; CD3D; HOXA1; ZNF43; SOX13; ZNF112; NKRF; TCF7; ATF2; CREB3; POU2AF1; SIX6; MXI1; ZNF224; NFE2L3; EHF; MED14; CDX2; GLI1; CNOT6; ZNF669; MYCN; ZNF331; HIPK2; REL; THAP11; LEF1; ZNF345; NR2F6; ZFP36L1; STAT6; HOXD1; E2F5; ZNF512B; ZNF589; FOS; TSC22D1; ZNF117; SPIB; APEX1; TBX3; GRHL2; BACH2; NR3C2; HES1; GLI2; LIN28A; RAD21; ATF3; TAL1; ZNF611; RNF138; ZNF85; CDK2; ID1; ZHX2; PMS1; HMGA1; MED17; RBFOX2; NKX3-1; ZNF423; NR4A2; DLX2; FOXA1; BRD4; FOXN3; IRF8; AHR; FLNA; NR1H3; PCGF2; GATA2; NFIL3; SOX2