Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID58109	Flupirtine	GSE92742	ASC	Human	24h	10uM	EID0324

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	CNOT2; RNF111; ELF5; HEY1; CARM1; MTA2; UBP1; TCF21; WWTR1; RNF10; NR2F2; TRRAP; HIPK1; RUNX3; CEBPZ; HDAC1; ENO1; CREB3L2; BCLAF1; TBPL1; NPAS2; CTNNB1; ZBTB11; TGFB1; NFE2L2; CSDE1; IRF2; DNAJC1; POU5F1B; BAZ2B; SP140L; ZBTB7A; SMARCA4; SNW1; USP22; CBX3; SFPQ; ADNP; IL16; KLF10; HMGN3; TBL1XR1; BRD4; NFYC; SAP130; AFF1; IFI16; BMI1; BAZ1B; PLAGL1; TCEB2; C1D; PIR; CCNA2; RBBP7; RBBP4; TRIM22; PRKDC; TBP; FOSB; RB1; ZBTB1; CREG1; CHD1; TSC22D2; CEBPA; SMARCA2; PIAS3; HTATIP2; DNMT3B; TFDP1; TBL1X; HES1; ISL1; RREB1; NR2F1; ATF1; FHL2; ZFP36L1; JAK2; ZEB2; CITED2; ID4; ZNF593; IRF1; STAT1; YWHAB; MECOM; SIAH2; TOB1; SOX9; PITX1; ID1; MAF; TLE4; HOXC6; ZNF652
Down-regulation	78	ABL1; CREM; BCL6; ZNF536; PHOX2B; RING1; NKX2-1; GATA6; RSF1; ZNF141; MYT1L; OLIG2; ZNF415; PCGF3; RBPJ; ARID5B; CERS6; DNMT1; HLF; PRDM2; HMBOX1; NKX2-2; LEF1; VPS72; FOXG1; TRIM29; POU2AF1; PBX3; BASP1; ATN1; BCL11A; ZIC1; TWIST1; NEUROD1; HIC2; FOXA2; ZBTB44; ZNF43; BACH2; ST18; SPIB; PBXIP1; E2F5; TBX3; OSR2; IRF6; ZSCAN18; PAX5; FOXE1; TULP3; RBFOX2; ZNF85; ZNF239; NR0B1; ATF3; SALL2; ZNF107; ZNF189; NR4A3; ZNF117; DLX2; HOXB2; MEIS1; CRK; ZNF331; MYB; TRPS1; TOX3; ZEB1; MEIS2; MYBL1; NFATC4; INSM1; WT1; ERBB4; NFKB2; NFIL3; NR4A2