Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57996	Afatinib	GSE92742	SKB	Human	24h	10uM	EID0323

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	GLI2; TSC22D3; VGLL4; DDIT3; BAZ1B; PSIP1; NPAT; RYBP; FOSL1; ATF5; STAT5A; SATB2; ATF4; BANP; TGIF1; ZNF589; RNF6; NFKBIA; CEBPD; JARID2; TWIST1; GTF2IRD1; TCEA1; SAP30; HIPK1; PAX6; TOB1; SALL1; DPF2; LYL1; CARHSP1; TSC22D1; BCL11B; MAFB; CREG1; ZNF516; BCL6; BATF3; CREB3; ELF5; SREBF1; ZNF232; NFX1; TRIM24; SHOX2; ZNF217; ARNTL2; KAT6B; SIX1; TBL1X; ARNTL; SMARCA2; NKX3-1; TLE1; EYA1; ZNF443; PITX1; KDM2A; TRIB3; HTATIP2; RFX5; ING3; ABL1; TRIP6; EYA2; ELF3; LEF1; NR1D2; BHLHE41; ENO1; MAF; XBP1; ZNF652; BTG1; PEG3; HMGN3; MSX1; KDM5D; ZBTB38
Down-regulation	67	FHL2; OLIG2; MYCBP; ZEB1; ERBB2; SUB1; RRN3; STAT1; ZBED2; MEF2C; ZNF493; GATA6; GFI1B; MYT1; TGFB1I1; PRKDC; WWTR1; HDAC2; IRF6; PTRF; MDM4; ZNF124; TGIF2; NFAT5; ARL2BP; SKI; TGFB1; FOXF1; CNOT3; SSX1; DLX2; MBD2; SOX11; MED24; CBFA2T3; RUVBL2; ILF2; CHD7; PBX1; TRIM22; IKBKAP; HOXA10; WNT4; JUN; MYB; SF1; ERG; SMAD7; ZNF512B; TCF4; ZFPM2; ZFP36L1; HOXB2; IRF4; ZNF423; HOXB6; NFE2L3; ID3; MAGED1; NR2F1; HES1; EGR3; EMX2; HHEX; TFAP2A; NR4A2; ZNF586