Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57966	Amonafide	GSE92742	SKB	Human	24h	10uM	EID0322

Response Information :

Types	Number	Response transcription factors
Up-regulation	298	RELB; GATA2; ETV1; ID2; KDM5A; SOX4; EGR1; MTF2; NFKBIB; ZEB2; HTATIP2; ISL1; POU2F2; PARP1; SUV39H1; PAX8; XBP1; POLR2A; NFE2L2; SMARCD1; ATF7IP; EP300; MDM2; ING3; THAP11; SSBP3; TBX2; KLF12; KAT6B; PAX5; SOX2; AFF1; ZMIZ2; MAFB; MSX1; FOXC1; SAFB2; AFF4; ZBTB18; DLX2; ZBTB48; SAFB; ZNF536; TBP; GMEB1; TRIM32; TOPORS; ZBTB25; MED25; IRF4; BACH1; TLE1; ZBTB39; ZNF253; ARID4A; SPIB; BRD8; NFATC1; PURA; CCNE1; KMT2A; RUVBL2; CREB5; MITF; DLX5; MNDA; ZNF165; HDAC4; ETS1; CDK9; BTG1; NFE2L3; PATZ1; VDR; TAF7; CREG1; SMAD7; ZBTB14; GFI1; YBX2; ZNF131; TSC22D2; RFX7; ZNF195; MLXIP; NAB1; TGIF1; BRPF1; SMAD9; TFEB; SIN3B; ZNF24; FOXA2; PMS1; CHD1; THAP1; TCERG1; HAND1; CHD7; ZNF443; MXD4; ZNF45; NELFB; YAF2; UIMC1; AATF; PPP1R13L; WWC1; EYA1; HR; HSF2; CIZ1; TRRAP; GABPA; ZBTB7A; GATA4; ECD; SP140; ZNF668; TCF20; HOXC6; NFX1; NFAT5; GMNN; PTTG1; POU2AF1; HHEX; BACH2; ZNF444; PHOX2A; NR2C1; RNF141; BAZ1B; NOC2L; ABT1; IL16; ZNF227; DLX6; BAZ2B; NR2F2; HMGN3; REPIN1; PPARGC1A; KDM2A; HLX; ELF2; FOXI1; EN2; EPAS1; BBX; ZNF692; SPDEF; NPAT; MKL1; CXXC1; VGLL4; NR3C2; NFYB; MLLT10; PHF8; SALL1; MTA1; JARID2; ID4; IRF9; RBL2; SOX10; KDM5B; HEY2; ZNF281; TRIM29; ZNF93; KAT2A; ZNF552; BCOR; PHOX2B; ELF1; FOXN3; MXD3; NRBF2; ZNF212; EHMT1; DLX4; PKNOX1; LIN28A; PROX1; TRIM16; CBX6; RNF111; CTNNB1; BCL10; THAP3; ELK1; CRK; ZNF282; DMTF1; TAF1A; GCFC2; ESR1; ZNF516; ZBTB1; C1QBP; FOXE1; PCGF3; ERCC2; POU2F1; ZNF273; HIC2; HOXB9; BCL3; ANKRD1; DRAP1; ZNF528; TEAD1; ZNF430; TSC22D4; SUZ12; KLF11; EWSR1; PAWR; HMGA1; AEBP1; SSX1; POU5F1B; TAF5; C1D; RERE; CITED2; RNF14; ZFHX3; MEF2A; MED7; RB1; ZIC3; SCAND1; SAP30; ETS2; HES1; SMARCA5; TCF4; IKZF5; ZNF84; HOXA11; WHSC1; ZBED2; TLE2; E2F8; ATOH1; LMCD1; KDM5C; PIR; ZNF423; JAK2; DDX54; PPARD; HBP1; PAX6; LPIN2; GLI2; XRCC6; ZNF222; JUNB; CBFA2T3; SOX9; MYT1L; PAXBP1; ZNF107; NR1H3; DR1; DNAJC1; TP53; RNF4; FOXO1; ZBTB38; MDM4; CEBPA; TAF10; LITAF; ZNF593; TCF7; HOXA1; GATAD2A; TCF12; ZNF232; ZHX2; ARID1A; DACH1; MAF; SERTAD2; LEF1; ID3; ZNF468; CTR9; FLNA; ABL1; NKX3-1; BASP1; ZNF586
Down-regulation	270	ATF5; BIRC2; HDAC2; KLF10; ZEB1; TRIB3; NFKB2; MAZ; SMARCA1; TSC22D3; EN1; CLOCK; DEK; HOXD1; TEAD3; NKX2-2; REL; UBE2B; RAD21; SOX11; RFC1; ATF3; BMI1; INSR; ENY2; VGLL1; IRF1; ZNF12; ZNF334; SMARCC1; ZNF83; HDAC5; ASH2L; HOXD11; HOXD13; THRA; IKBKAP; CALCOCO1; CCNC; ZMYM2; RNF2; PBX1; ZNF512B; STAT3; HOXB13; DNAJC2; HOXA4; ZNF248; SMARCD2; RBFOX2; ZNF606; TAF11; SCMH1; FOXK2; SIX6; USP22; USP21; VPS72; FEZF2; MTDH; BRD7; CBX3; COPS5; FOXA1; CBFA2T2; TAF6L; PCBD1; MKL2; TGFB1I1; CEBPZ; POLR3C; ZNF224; TFAP2A; IFI16; SMAD1; ZNF787; PMF1; TOX3; RBPJ; CERS6; SMARCE1; TULP3; CCNH; SRF; PSMD9; ZNF177; ZNF345; ZNF135; ZNF74; ZNF623; ZNF440; TRIM22; ZBTB16; RORA; KAT6A; ZFPM2; TAL1; HCFC2; RREB1; ARL2BP; PBRM1; MYOG; CBX4; BRD4; PRKDC; BCLAF1; ZNF358; BNC1; RYBP; FOXF1; TCEA1; LOXL2; TEAD4; SMARCD3; GTF3A; HOXD9; HOXB2; ARID5B; CUX2; TOX; SOX13; PCGF1; ITGB3BP; YEATS2; MED24; SMARCA4; MAGED1; CDYL; CBFB; TCEA2; MYCL; NCOR1; CSDE1; NUP62; EGR4; ZNF112; L3MBTL1; RFXANK; HLF; RXRG; KLF1; SUB1; ZNF133; BPTF; MYT1; HOXB5; GTF2IRD1; PITX1; SUMO1; MED13; MMS19; ATN1; ZFP30; RELA; MEF2D; MYBL2; NPAS2; SETDB1; GFI1B; BARX1; ZNF813; TDRD3; STAT5A; AR; MEIS2; PBX3; LZTS1; TAF1D; PSIP1; ZNF544; BTF3; LHX2; CHD3; CITED1; ZNF264; UBTF; CREB1; RING1; HIF3A; YWHAB; ZNF266; ILF2; ZNF148; HABP4; NFIC; MYC; CDK2; TCF21; ZNF573; FOXO4; DAXX; AHR; ZNF587; NONO; ZKSCAN1; INSM1; SP100; SUPT4H1; MEOX2; NR2F1; MEN1; WWTR1; CRYM; ZNF274; ZNF329; PHIP; SIX1; ZNF415; HEY1; ELK3; RNF10; ETV5; CREB3L2; WT1; ATF6; SSBP2; TAF9B; APEX1; TFEC; HMGB2; MAFF; ZBTB11; NHLH2; TBL1XR1; PCGF2; ZNF667; ZNF91; HOXA5; PLAG1; ACTL6A; SAP18; SOX12; SMAD2; ARID4B; FOXF2; SMAD3; CNOT6; CREBL2; RLF; ZNF160; STAT4; PEG3; PKNOX2; ZNF432; STAT6; ERBB2; BHLHE41; SOX17; ZNF611; MEF2C; FOXJ3; DNMT1; SNAI2; MEIS1; TFAP2C; NCOA2; ZNF551; NFKBIA; ID1; TMF1; STAT1; EMX2; ZIC1; KDM5D; ZNF721; KLF6; TLE4; ZSCAN18; TRIP6; NR1H2