Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57949	Afatinib	GSE92742	SKB	Human	24h	10uM	EID0322

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	ATF5; CREG1; FOSL1; HOXC5; CBFA2T2; PRDM10; ELF5; ZNF770; PHIP; MXI1; PAX6; HTATIP2; HMG20B; PBX3; ZNF652; DDIT3; SPEN; SHOX2; TDRD3; FOXM1; HDAC4; HDAC1; HOXC4; ST18; CERS6; PIAS1; HMGA1; PHOX2B; ZNF232; SIX3; NPAS2; TDP2; ZFHX3; JAK2; VGLL4; TRIM29; EHMT2; STAT5A; SAP130; NFKBIA; BANP; SOX13; HLX; DACH1; MYCL; HOXB5; EYA1; ZNF589; PHF1; ZNF93; TRPS1; BHLHE41; MED15; SREBF2; SALL1; CERS4; KDM5C; MEIS2; ZSCAN31; ZNF426; BCL11A; MYBL2; HIRA; MNDA; TOB1; SOX9; MEIS1; HOXB2; MAFB; TBL1X; TBX3; FOXF2; SNAI2; TCF21; HOXB6; ZNF91; MYRF; TSC22D1; HOXC6; HOXB7; ABL1; ZNF331; WT1; EMX2
Down-regulation	69	FHL2; ERBB2; MYCBP; TRIM22; RUVBL2; HDAC2; ZMYM2; CREB3; CRK; CBFB; TGFB1; RHOA; NLK; NEDD8; SMARCD3; MAGED1; WWTR1; SMAD2; MEF2C; CCNC; ZNF267; TBX1; RBBP8; UBP1; TERF1; TSG101; NUP62; MYT1; POU4F1; ELK3; TLE2; XBP1; CDYL; TCF12; PLAGL1; IRF7; SMARCE1; SUB1; CBX3; SMAD3; SMARCA1; HMGB3; ID3; TRIP6; IKBKAP; NFIB; E2F3; PUF60; STAT1; SMAD7; ZBTB38; HLF; HIPK3; ZNF226; USP22; MBD2; MEOX2; TGFB1I1; RBPMS; ERG; C1QBP; ZEB1; TCF4; ZNF587; ASCL1; KDM5D; KLF2; FOXJ3; ZNF586