Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57924	Azd-7762	GSE92742	SKB	Human	24h	10uM	EID0322

Response Information :

Types	Number	Response transcription factors
Up-regulation	139	CEBPD; NFIL3; SOX2; PNRC1; KLF9; PPARG; MTF2; TSC22D3; SOX4; HSF1; VDR; TOPORS; FOXO4; DLX2; CDC5L; THAP4; ZBTB20; MSX1; ZNF696; ELF2; RAD21; PEG3; ZNF500; CBX4; MDM2; MKL2; TERF1; TERF2; ZNF250; SAFB; ZNF107; CDIP1; POLR3C; ZNF195; TRPS1; PAX6; RBBP8; ETS1; PURA; ZNF34; SPDEF; ZNF354A; ZNF516; JUNB; TGIF1; NR4A1; BARX1; ZNF623; ZBTB16; ZNF7; SPEN; ETS2; PHIP; VGLL4; CD3D; ZNF267; PIAS3; ARNTL; PGR; BTG1; TAF12; ZNF232; TRIM24; NR4A2; NR5A2; ZNF273; PDLIM1; CREB3L2; ZNF12; EHF; BCL6; TFDP2; CIR1; ZNF85; ZNF165; MXI1; HLX; PPARD; TCF21; ZKSCAN4; HMG20B; BACH2; TCF25; GLI2; ING2; INSM1; BANP; ID3; HOXA1; IRF9; NPAS2; ESR1; SMARCA1; PFDN5; THAP11; ABL1; KMT2A; ID4; MEIS2; DLX5; HBP1; SPIB; MEIS1; ZNF131; ZSCAN18; MYCN; MBD1; ZNF573; EYA2; CHD9; TXNIP; SMAD1; IFI16; STAT4; TWIST1; FOXG1; ZNF667; HEY1; ERBB4; NR1H3; EHMT2; IRF6; FOXO1; HMGB2; ZNF331; TOB1; HMGN3; NR1H2; SNAI2; POU2AF1; FOXF2; TSC22D1; DMTF1; WT1; JUN; ASCL1; ID1; ZNF91; HHEX
Down-regulation	89	ERBB2; PUF60; DRAP1; YWHAB; PMF1; MED27; GTF3A; HNRNPD; RHOA; PTRF; MAGED1; LOXL2; HDAC2; PSMD9; TP53; MED24; MAZ; KAT7; EDF1; BHLHE41; ASH2L; MEF2C; PRKDC; TRIM16; NCOR2; BRD7; SUB1; SMAD3; SMARCC1; FLNA; TCERG1; SAP18; IRF8; SP2; NCOR1; ECD; IKBKAP; UBP1; SREBF1; ZMIZ1; PCGF2; ZEB2; XBP1; CTBP1; NFE2L3; FOSL1; PCBD1; KAT6A; CTNNB1; NONO; SOX9; APEX1; KDM5D; NCOA4; MYCBP; C1QBP; HDAC9; MAF; HMGA1; EMX2; SOX11; IRF7; TSC22D2; SCAND1; ZNF226; TBL1XR1; RBBP5; DDX5; NFYC; AHR; PIR; CBFB; TRIP6; TGFB1; SIRT7; TOX3; CREB3L1; ZFP36L1; ZBTB18; NKX3-1; KLF2; KLF6; MYC; YBX1; HOXB7; ZIC1; HOXC6; BASP1; ZNF586