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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID57923 Alvocidib GSE92742 SKB Human 24h 10uM EID0322
Types Number Response transcription factors
Up-regulation 99 ESR1; MEIS1; MED25; ID4; LHX3; POU2F2; DLX2; SSBP3; NR5A2; SOX2; HAND1; RING1; MXI1; ZNF816; PRDM1; ZNF500; ARNTL2; FOXJ1; SOX17; ZNF467; TFDP1; NR4A3; MED12; LIN28A; SSX1; MYCN; ZNF273; HLX; CREG1; ZNF253; DACH1; PHF1; HOXC4; BCL11A; ZNF423; BRD7; IRF6; ZBED2; TRPS1; CREM; ZNF665; PITX1; CHD7; PRDM14; HOXB5; TAF12; PFDN5; NR0B1; TCF21; PDLIM1; LEF1; TBX21; MSX1; ARID3B; PBX2; ST18; MYB; TCF4; EHMT2; KDM5C; DRAP1; NFATC4; TCEB2; PEG3; BCL11B; FOXF1; TWIST1; SALL2; NR2F1; NKX2-2; DLX5; ZNF107; MEIS2; AR; NR4A2; SREBF2; HIRA; PHIP; SPDEF; EHF; IRF9; MECOM; CD3D; ZNF117; ZNF611; AEBP1; CALR; TAF9B; MYCL; ZNF85; ZNF331; ZSCAN18; VPS72; ZNF415; WT1; ATF3; ID3; ERBB4; ZNF586
Down-regulation 175 FHL2; BIRC2; TSC22D3; TRIM22; CRK; ZMYM2; HNRNPD; FOXO3; RBPJ; TFAM; BRD4; USP22; INSR; SCAND1; ZBTB7A; ZNF146; PUF60; CLOCK; ZBED4; APEX1; RNF138; HCFC2; ZNF263; PSIP1; TRIM32; MED17; NUP62; SMAD2; SFPQ; NCOR1; ZZZ3; PPRC1; ERBB2; CHD8; KAT8; EN1; NR1D2; CBFB; DNAJC2; CARM1; PCGF1; BBX; IKBKAP; SIX2; SF1; XBP1; SIX1; KAT7; MAGED1; FOSL1; HDAC2; NFKBIA; MED27; RYBP; ZNF12; TRIM28; BCOR; MED24; UBE2I; NCOA4; VGLL4; RBM14; EGR3; CDK7; RAN; UBE2B; GTF2IRD1; FOXC1; SREBF1; REST; CDYL; TP53; MAX; RUNX1; MNT; WWTR1; BMI1; NCOR2; KLF2; SMARCD2; BTG1; TEAD4; PHF20; CREB3L1; DDIT3; ZBTB24; JUNB; PATZ1; DDX17; ATF4; NR2F2; MED1; CEBPD; MEF2A; ZBTB16; JUND; FOXN3; KLF10; AHR; HOXA10; SMAD3; E2F3; NELFB; CCNC; BCL10; CTBP2; TBP; DEK; BCL6; REPIN1; CREB5; BLZF1; PCGF2; ZBTB11; CBX3; GTF3A; AATF; TRAK1; TRIP6; TP63; TLE1; CENPB; MED23; TRIM27; SNW1; SMAD1; ELK3; OSR2; DDX5; ZFP36L2; SMARCD3; HSF2; NRBF2; ARID4B; SMARCA2; CEBPG; NFYC; RBBP4; NKX3-1; ZNF512B; RRN3; TSC22D2; KDM5D; CCDC59; CTBP1; ADNP; TBL1X; MEOX2; FOXO1; FOXJ3; LPIN2; KLF6; ZBTB38; CHD9; YWHAB; NFIB; SMAD7; TRIM29; TCF12; CUX1; SAP30; SERTAD2; TMF1; YBX1; TFAP2C; CTR9; MEF2C; TOX3; KLF4; MYC; ABL1; ZNF432; BASP1; HOXC6; HOXB7
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