Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57915	Amonafide	GSE92742	SKB	Human	24h	10uM	EID0321

Response Information :

Types	Number	Response transcription factors
Up-regulation	277	MTF2; ZNF131; NFKB2; GATA2; ETV1; ZNF586; ADRB2; RELB; MXD4; KMT2A; FOS; EHMT1; GCFC2; PARP1; MDM2; SPIB; CCNA2; GLI1; KDM5A; SERTAD2; BACH2; MDM4; SMARCD2; BRCA1; NELFB; PCGF3; PAX5; ZBTB39; NFE2L2; EGR1; POU2F2; CBX6; CDK9; KMT2B; GTF2I; PAX8; CCNT1; ZBTB25; ZNF10; RFX7; ZNF227; BRWD1; TBX2; PAXBP1; TOPORS; NFYB; HR; WWC1; TAF1A; ZBTB6; BAZ2A; HMGN3; MBD4; ING3; THAP11; TAF7L; NFATC1; NPAT; AEBP1; BANP; MGA; ZNF506; MZF1; FOXE1; ZNF165; TRRAP; HTATIP2; CIITA; EDF1; ZBTB7C; CREG1; JUNB; SCAND1; TAF1; KMT5A; KLF9; ZNF93; ZNF253; HOXB9; EPAS1; BRCA2; MYT1L; ZNF180; TRIM25; ZNF335; BAZ2B; NFATC4; CHD8; NR3C2; RBL2; CHD1; HOXA1; TGIF1; ZNF671; GATA4; ZNF232; KDM5B; MKL1; NFKB1; MXD1; ZBTB48; PTTG1; PPP1R13L; PML; PNRC1; CERS4; SSX1; NFX1; SALL1; ZNF225; ARRB1; ZNF688; HOXC6; DPF2; CIZ1; FOXI1; AFF4; MSX1; TCF15; ZNF281; BTG1; ZNF552; REXO4; PIAS1; ZNF211; BLZF1; MITF; FOXL2; ZNF770; BBX; IRF4; KLF11; TAF5; CBL; ZNF43; CEBPA; WDHD1; JAK2; EP300; ZNF675; TCF20; DLX5; ZNF493; GFI1; PDLIM1; CNOT3; AFF1; KAT6B; NOC2L; ZKSCAN5; ZNF134; DMTF1; ZNF443; ZNF195; BACH1; PREB; ATF7IP; POU5F1B; POLR2A; GLI2; WHSC1; PBX3; TEAD1; STAT5B; ZNF528; MLLT10; SNAPC4; TRIM29; KDM4C; ZBTB20; SOX2; ID2; ELF1; ZNF354A; HOXA7; TFEB; CDIP1; PHF8; NR5A2; ZNF222; SAFB; MED1; KDM5C; CUX1; CBFA2T3; NFYA; ZBTB43; TAF9B; ISL1; THAP7; MED21; TXNIP; TSC22D2; TGFB1; CCNE1; ZNF107; ZBTB44; TERF1; RNF141; BRD2; PURA; EN2; HLX; SIN3B; ID3; ZNF189; PRMT2; ZNF557; LIN28A; TFAM; ZBTB14; ATOH1; RUVBL2; TCF4; NRBF2; DNMT3B; MYRF; BRPF1; ZNF268; ZMYND8; ZNF536; CREBZF; FUBP1; GABPA; ZNF331; HOXA5; SAFB2; YBX2; BCL3; DLX2; PLAGL1; FOXN3; TULP4; NEUROD1; ARID4A; RCOR1; TSC22D4; PFDN5; STAT4; CENPB; NR1H2; NKX2-2; RNF4; SOHLH2; SOX4; TAF10; MLXIP; E4F1; LEF1; VDR; ZFP36L2; DNAJC1; TLE1; POU2AF1; E2F8; REL; PIR; SMAD1; ZBTB38; IRX5; LITAF; PITX2; BCL11B; MTA1; SPEN; RNF14; ZBTB18; HHEX; MAFB; ZEB2; KLF2; RBM39; ELF5; HOXB7; PAX6; TSC22D1; MEIS1
Down-regulation	254	CRK; ATF5; DEK; VGLL4; BIRC2; IKBKAP; PSIP1; HDGF; NCOR1; CDYL; ZFPM2; NPAS2; TSC22D3; TGFB1I1; PKNOX2; ZMYM2; PCGF2; CLOCK; ZNF587; TFEC; ZKSCAN1; SCMH1; SATB2; USP21; BMI1; MYC; PCBD1; TCF12; CBFB; AR; PBX1; RLF; ELF4; SMARCA1; KLF10; TDP2; FOXA1; SMAD2; MTDH; ENY2; TEAD3; ETV5; NONO; SUB1; RBFOX2; THRA; GFI1B; TCF7; TAF11; SMARCC1; ILF2; HMG20B; EN1; ELK3; ZNF44; ZEB1; CDC5L; TCF7L2; MED24; SP3; GMNN; SOX9; TBL1XR1; MED13; ZBTB11; MAZ; RFC1; CALCOCO1; MYT1; SP100; TOX3; MEIS2; ZNF606; HDAC5; NCOA4; ATF6; AHR; TERF2; ASH2L; SUPT4H1; HOXB13; TOX; NUP62; YEATS2; FOXK2; APEX1; CBX3; KAT2B; LOXL2; E2F3; OLIG2; ZSCAN12; KLF1; MAFF; ZNF248; TRIM24; SMARCE1; GTF2IRD1; ACTL6A; TAF9; SAP30; MNDA; SMARCD3; ZNF415; LDB1; CERS6; ERBB4; HEY1; CSDE1; L3MBTL1; RXRB; GRHL2; BHLHE40; HIPK1; CRYM; PMF1; ZNF787; NFE2L1; SLC2A4RG; WIZ; STAT1; ZNF76; STAT3; LMCD1; CD3D; IFI16; CREB3L2; HOXD1; UBE2B; RAN; HIF1A; HDAC2; ING2; RAD21; SIX2; INSR; TEAD4; TAL1; FOXO4; SRF; BPTF; MYF5; ZNF160; SIX1; VPS72; ITGB3BP; MLX; ZNF264; SND1; USP22; CBFA2T2; MBD3; MYCL; ZNF580; SP140L; CUX2; RXRG; CREB3L1; ZNF611; STAT5A; SMAD3; SETD3; TRIM22; RNF138; ID4; ZNF721; RBPJ; ZNF274; ATF3; TFCP2L1; PRRX1; SETD2; TFAP2A; MXI1; UBP1; MDFI; ZMIZ1; ERG; GTF3A; VGLL1; ATF1; EHF; TOB1; DNMT1; FHL2; ATN1; POLR3C; MNT; ZNF652; ZFP64; CBX5; KLF7; EYA1; ZZZ3; SMARCA2; CRY1; MAGED1; ZNF91; HMGB3; ZBTB16; SUZ12; HMGB2; CCNC; CNOT2; PBRM1; FOXJ3; RREB1; NR1H4; MEOX2; WWTR1; SALL2; ZNF512B; FOXG1; HDAC4; ZNF22; ARID4B; HMGXB4; MYBL1; HOXA10; MECOM; RARA; SOX11; TRPS1; STAT6; GATA6; ZNF665; ZNF432; SSBP2; PTRF; PHF20; URI1; MKL2; ZNF83; KLF5; ESR1; YBX1; CREBL2; INSM1; NR4A1; FOXF1; CDK2; MBD2; ENO1; IRF1; ZBED2; MNAT1; EGR3; RNF6; ASCL1; KDM5D; NFATC3; DAXX; PEG3; TRIB3