Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57911	Alvocidib	GSE92742	SKB	Human	24h	10uM	EID0321

Response Information :

Types	Number	Response transcription factors
Up-regulation	158	IRF6; KLF9; DACH1; ZNF273; HIRA; SPI1; FOXA2; ERBB4; NR5A2; PROX1; ID4; NR4A3; CDX2; BNC1; THRA; ATF3; YEATS4; INSM1; HOXB9; REL; NFATC4; CALR; EHF; BCL11A; ST18; TCF7; ZNF107; HMGN3; SUPT3H; FOXJ1; NHLH1; TWIST1; MEIS2; VPS72; TFAP2A; MYBL1; THRB; TFDP2; LEF1; ZNF665; SIX6; LIN28A; ZNF43; CUX2; TBX21; ATOH1; SOX21; PAX5; SIX3; PSMC3; ZNF117; ZNF141; ZNF44; ZNF85; LHX6; SSX1; KLF13; ZNF467; PRDM14; ZNF131; JUN; TULP3; SHOX2; AEBP1; DBP; CDIP1; ETS1; GRHL2; EGR1; HOXA1; ID3; ID1; CBFA2T3; CDX1; ZIC3; HMBOX1; MYB; PAX6; ZSCAN18; ESR1; EGR4; TCF4; ZBED2; MYBL2; ZNF91; TAL1; HLX; NKX2-2; ZNF415; KDM5C; HOXD1; BCL11B; MYCL; LHX3; SREBF2; MED25; SOX17; OVOL1; ZNF140; HIPK2; CEBPD; ZNF586; FOXG1; ZNF611; CD3D; CREM; NR1H3; MXD1; MYRF; KLF7; DLX5; FOS; PHIP; CHD7; TGFB1; ZNF22; MYCN; PGR; BARX1; HDAC5; FOXE1; NEUROD1; ZNF93; NR1H2; HOXB5; ATN1; ZIC1; HMGB1; TOX; WT1; FOXF1; FOXF2; SALL2; PFDN5; HAND1; MSX1; PITX1; NR4A1; ZNF711; IRX5; DLX2; MEIS1; NKX2-1; ZNF160; ZEB1; HLF; ZFPM2; ZMIZ1; ZNF721; TRPS1; KLF5; TOX3; ZBTB20; SOX2; PBX3; NFE2; NR2F6; TRIB3
Down-regulation	277	FHL2; MYC; FOXO3; BIRC2; TSC22D3; CRK; TBP; TRIM28; NFYC; SCAND1; NCOA4; SMARCC1; PUF60; XBP1; ABL1; PCGF2; CEBPZ; YBX3; ERCC3; ECD; MEF2C; NUP62; CREB3L1; KAT5; ELK3; SNW1; NR2F2; UBE2I; ZFP36L1; MED1; CCDC59; DPF2; AATF; ZNF593; APEX1; HNRNPD; ZNF112; ATF4; NCOR1; THAP11; IKBKAP; KAT7; ZNF32; SP100; SMARCD2; NPAS2; HCFC2; SUB1; SIX2; MED24; SF1; NFKBIA; NONO; SMAD2; ZBTB11; SP110; TBL1X; ADNP; TRAK1; YWHAB; ZNF302; AFF1; LIMD1; SMARCA4; ZNF212; RELA; ZBTB24; TRIM27; TP53; DDX17; MLX; HCFC1; CTR9; ZBTB1; RBM14; BMI1; SAP30; NRBF2; SETD2; ZBTB7A; FOXO1; KDM2A; ERBB2; PLAGL2; SMARCD3; MAF; KDM5D; NCOA6; MAX; MYOD1; TRIM32; ING2; ZMYM2; CTBP1; NFKB1; MDFI; STAT5A; HOXA11; BLZF1; BAZ1A; CNOT6; HSF2; CDK7; HOXA10; BTG1; PKNOX1; BHLHE40; FLNA; SMAD4; THAP1; ZZZ3; MED23; REST; BASP1; MAGED1; ZNF528; FOXD1; TCF12; MED17; ARID4B; RERE; BRD3; SP3; DNAJC2; ZFP64; ID2; HMG20B; VGLL4; SMARCA5; PIR; SMARCE1; COPS2; SERTAD2; RNF4; NFE2L1; RNF10; ZKSCAN7; PPRC1; TRIM16; TGFB1I1; FOSL1; RBBP4; HDAC2; LOXL2; HOXC6; EDF1; ZNF263; NKRF; CARM1; KLF2; NSD1; NFIL3; RBPJ; RBBP5; DR1; TAF1D; CTCF; PHF20; RAN; NELFB; BRD8; ZNF227; TEAD4; BCLAF1; ETV5; TAF5; SNIP1; SND1; KAT8; RLF; MED7; DEAF1; ATF7IP; C1QBP; AHR; RUNX3; PATZ1; ZNF24; SREBF1; MMS19; POLR2A; SIX1; POU2AF1; HDAC4; DDX5; OSR2; RB1; ZNF274; ELK1; MED6; MED4; HMG20A; TAF10; ADNP2; DDX54; TFAP2C; HOXB7; MEF2A; USF2; HMGA1; TRIM22; RNF138; SMAD3; ASH2L; ZNF410; FOXJ3; ZNF23; IRF2; LPIN2; UBP1; BCL10; NCOR2; PIAS2; ZNF146; REPIN1; ZBTB38; FOSL2; BRD2; NKX3-1; USP22; SFPQ; CITED2; ELF1; WWP1; KAT2B; MBD2; BAZ1B; ZNF189; TRIP6; ZEB2; HDAC1; HMGB2; VEZF1; WWTR1; SOX4; MNDA; STAT6; JUNB; SOX9; BBX; EZH2; SMARCA2; DDIT3; BHLHE41; RUNX1; MTDH; YBX1; RNF6; SP140L; KLF10; URI1; ZNF217; TBL1XR1; CHD1; SMAD7; TOB1; NRIP1; EYA2; GTF3A; CBX3; RBPMS; PLAG1; TSC22D2; STAT1; BRD4; MAFB; TBPL1; UBE2B; JARID2; RREB1; HOXA5; INSR; MNAT1; DAXX; SSBP2; TBX3; ZBTB18