Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57872	Sitagliptin	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	SOX2; PPARD; IRF6; ZIC3; FOXN3; BRD7; KLF4; POU5F1B; NR5A2; ID1; ZNF532; KLF13; MBD1; ZNF165; UBE2L3; NR4A3; NHLH2; PRDM14; NANOG; KLF11; PAWR; PRDM2; PBX1; LIN28A; HIF3A; THAP7; TP63; CDIP1; CSDE1; EMX2; TGS1; HBP1; PBXIP1; MYCN; MEIS1; CREM; FEZF2; BACH2; VPS72; CDK2; MYBL2; ATN1; HOXB2; MYBL1; TERF2; EPAS1; TGIF1; KLF5; TERF1; ING4; PAX6; XRCC6; ZMIZ1; TCEA1; ZNF75D; INSM1; DLX2; KDM5D; IFI16; ETS1; RYBP; KLF9; TCEA2; ZNF589; YAP1; TDP2; LMCD1; HOXD1; TFAP2A; SNAI2; ELF5; PBX3; ZFP36L2; HIC2; BTG1; PSMC3; NCOA3; RBFOX2; BASP1; FOXM1; MECOM; FOXG1; ID3; CALR; GMNN; ARNT2; CREG1; HMGB3; DDX17; INSR; TFCP2L1; TCF7L1; PHF20; HEY1; PMF1; FOXO1; NCOA2; ZNF302; FOS; FHL2; BCL11A; EHF; ENY2; HMGN3; NR2F6; TBX3; GTF2A2; SOX17; BRD4; NR4A2; HOXB6; TSC22D3; ZFP36L1; MAF
Down-regulation	121	ZNF3; GTF3A; TSC22D4; HMG20B; REPIN1; FOXO3; MLX; PBX2; MED13; ZNF14; ADNP; BMI1; MNDA; NCOA4; ZNF593; RCOR3; ZMIZ2; ZFP64; MED1; KDM2A; SERTAD2; MAX; RBM14; SCMH1; STAT3; BRD8; ZNF587; ASH2L; DNMT1; HLTF; MSC; RNF6; SFPQ; ZNF671; ZBTB11; ESR1; PIR; TEAD1; NEDD8; CHD1; AHR; SMAD6; ZNF211; ZNF629; SIRT7; NONO; TRIM27; TAF4; BRD2; ZNF394; ZKSCAN1; ZBTB25; TRIM28; CUX1; SMARCD2; ZNF217; PITX1; STAT5A; CREB3L2; CD3D; KDM5B; RXRB; KAT7; GABPB1; HDAC6; SAP30; IRX5; PRRX2; LPIN2; TRRAP; EGR3; TBL1X; PCGF2; BAZ2A; IRF5; RUNX3; DNAJC1; BRPF1; ETV5; ELK3; RORA; USF2; TBPL1; NR1D2; ZNF205; HDAC1; FOXD1; NFYC; ELF4; WHSC1; BCL11B; BAZ1A; SMARCD3; PURA; HOXA5; CDK8; ING3; HMGB2; SMAD3; ZBTB18; IRF8; TCF7; HLF; PSPC1; DRAP1; ZMYM2; EZH2; TBP; ASCL1; ZEB2; LEF1; EYA2; TBX2; FOSL1; TAL1; IRF7; MAGED1; HOXC6; CREB1; ZNF586; NR3C1