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Overview Perturbagen Expression Profiles Transcriptional Responses
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Overview Perturbagen Expression Profiles Transcriptional Responses
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Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID57866 Ki-16425 GSE92742 SKB Human 24h 10uM EID0320
Types Number Response transcription factors
Up-regulation 351 IKZF1; BRCA1; GLI2; ETV1; GATA2; ARNTL2; PAX8; HOXD13; TCFL5; POU2F1; E2F2; ZNF189; SUV39H1; DNMT3B; LHX6; NR1I3; SOX2; TBX21; ZNF248; CREB3L1; PITX3; HDAC11; FOXN3; AIRE; CSDC2; MAPK8IP1; RXRG; TCF4; IRF5; DNAJC1; EED; TCF21; ACTL6B; NKRF; MAP3K10; GATA1; ZNF510; RBL1; PSMC3IP; NR2F2; WHSC1; ATF6B; ZSCAN2; NR2F1; ZMIZ2; MNAT1; NR6A1; MBD1; EP400; CEBPA; CCNA2; HOXB8; LHX1; KLF6; NKX6-1; SOX5; CBX6; PATZ1; MYBL2; RNF4; FHL5; PAX6; HLF; KMT2A; SATB2; ZNF711; DYRK1B; EGR2; PRDM2; OVOL1; KLF15; BRCA2; SMAD1; TEF; TXNIP; HOXD12; UBE3A; ZNF493; BRIP1; NFE2; IFNB1; PAX3; DOT1L; CBX7; GFI1B; NEUROG2; KLF1; HNF1A; ETV3; PLAG1; PRDM12; ZNF45; POU3F3; CREBZF; ZFP2; TP63; CIITA; EGR4; LYL1; PROX1; NFRKB; FOXE1; ZNF423; ZNF446; PBX2; POU4F1; SOX21; KDM5A; NUP62; PAX1; ZIC3; NFKBIB; ZNF75D; TOX3; SHOX2; KDM5B; TAL1; RFX1; FOXJ2; HOXA6; SNAI1; SNAPC4; TAF7L; ZNF10; LHX3; LMX1B; DCC; MZF1; WNT4; HNF4A; ZEB1; MAFG; ZNF215; TAF1; ARID3A; BCOR; TRIM24; KLF3; NHLH1; ZNF362; ZNF384; EDF1; CEBPZ; MDM4; OSR2; TFDP2; PRDM5; ASCL1; FEV; HEYL; MED23; SOHLH2; FOSL1; CBX2; HOXB1; CASZ1; FOXB1; SOX3; RFX2; MBD4; TBL1X; ZNF254; CARHSP1; ZNF688; ETS2; ZNF516; DAXX; EPAS1; STAT5B; PPARGC1A; TBL1XR1; EP300; MYT1L; ZNF391; ZBTB20; ZSCAN9; HMGN3; BMI1; TFAP2B; POU3F4; CDK9; PML; AEBP1; ZNF24; SSX3; TAF1A; ZHX3; ZBTB44; ZNF224; SOX13; ZNF408; SIX6; TAF1D; UBTF; WDHD1; INSM1; HOXB5; MLXIP; ELF4; CBL; ZBTB16; TBPL1; EMX1; ZNF335; CARF; CBFA2T3; NR1H3; PRRX1; ZNF236; LIMD1; ZBTB48; HOXA3; ZNF180; NR4A1; ZNF672; ZNF467; ZEB2; HR; ZNF324B; FOXJ3; PRDM1; THAP7; TTF1; SOX11; MEOX1; HDAC4; PKNOX1; THRAP3; MXD4; GATA3; TBX2; ZNF506; ZFHX3; FUBP1; NPAS1; BHLHE41; SALL1; RFX5; HOXC4; ARID3B; BRWD1; ZSCAN16; RBBP5; ZNF212; NR3C1; HOXC8; PBXIP1; RREB1; WWTR1; CAMTA1; PGR; SATB1; ZNF267; PRMT2; KLF5; KMT2D; CIR1; CHAF1B; HNF1B; WWP1; ZFPM2; MYCL; TFEC; ZXDC; SOX18; NR5A2; ZNF257; EZH1; ING2; RFX7; MEOX2; CXXC1; GATAD2A; HOXC6; AFF1; SRY; SIM2; MAFB; TLE4; JAK2; HLX; TLX3; BCL11B; MYB; KLF10; ADRB2; LHX2; CDX1; PAX5; FOXF1; ZNF589; MYF6; BATF3; BCLAF1; GON4L; ID1; SSX7; TCEA2; ZNF721; NPAT; BARX1; ZNF200; KLF2; INSR; MTA2; HOXB13; ZSCAN5A; MLLT10; ARID4A; ZKSCAN4; BNC1; IRF4; ZNF160; GFI1; MEIS1; EYA1; BLM; AATF; CITED2; ZNF227; GRHL2; ZNF93; CDX2; GLI1; HOXA1; HEY2; FOXJ1; ARNTL; BASP1; NEUROD1; NFKB2; SIX1; TAF9B; FOXA2; FOXG1; BAZ2B; DBP; ID4; ZNF175; MEF2C; ERG; PPARG; HMGB3; FOXL2; CREG1; BTG1; HOXB7; EGR3; SNAI2; SCAND1; FHL2
Down-regulation 469 RUVBL1; BRD7; TRIB3; SP3; HBP1; MYC; DPF2; TULP3; TP53; PEX14; SUMO1; THAP4; TFDP1; ZNF665; MED13; COPS5; SIRT2; XRCC6; GTF3A; WDR77; ZNF281; ATF3; BANP; PPP1R13L; ENO1; TCF25; RARA; DEK; CEBPG; SMARCA1; CDIP1; ZNF331; MED21; MED4; HDAC5; CALR; MLX; E2F3; SF1; CBFB; HCFC1; CEBPD; ZNF668; ZNF12; CTCF; HTATIP2; SOX12; PBRM1; TWIST1; CNOT3; MTDH; ARID1A; UBP1; ZNF195; ZKSCAN1; PARP1; ELF1; SUPT7L; ZNF426; ZSCAN18; RFXANK; TEAD4; ATF2; ZNF580; ZNF552; ZMIZ1; GTF2A1; TSHZ2; TFAP2A; GTF2F1; ZNF146; RLF; RHOA; ZNF232; ABT1; ZNF444; PRPF6; BACH2; ATF5; TFAM; VEZF1; TSC22D4; ADNP; PA2G4; IRF2; HMGXB4; MYBBP1A; MYRF; NCOA3; ZNF329; DR1; CDK7; NR1H2; TCEA1; RING1; ZNF646; TRIM29; NFYA; MEN1; RBBP8; XBP1; CREB3L2; TGFB1; APEX1; SSBP2; ZFP36L2; NFKB1; TGIF1; TRIM27; ZNF302; TOX4; PIAS4; SRF; STAT1; CENPB; CAMTA2; MDFI; RNF2; THAP1; VGLL4; ELF5; RBBP4; PPRC1; ZNF148; CHD4; NCOR1; SALL2; ZBTB11; BCL10; MED15; CCNH; SMARCA5; ITGB3BP; CREBL2; MED20; SMARCD3; RNF138; RAD21; GMEB2; PEG3; MDM2; JUNB; ZNF131; RXRB; NFYC; FOXK2; GTF2IRD1; SAP30; REST; TEAD1; E2F6; HIPK1; BRD2; RUVBL2; SMAD4; SIX5; TRIP6; CDC5L; YEATS2; TAF6; SUPT6H; DDIT3; ZNF44; CSDE1; TAF5; ZNF544; ZNF14; SMARCB1; ZNF32; PSIP1; DRAP1; SCMH1; EN1; JUN; NFAT5; WIZ; ZKSCAN7; KAT6A; MEF2D; KAT2A; RB1; SRCAP; DDX54; ILF2; SREBF1; SERTAD2; HMGB1; RBM14; NR2C1; SKIL; TAF11; HMGXB3; ZNF606; SND1; AFF4; CREB3; CEBPB; HOXB3; NPM1; AES; EHMT2; STAT3; YAP1; ZNF415; ZNF264; MYCBP; PITX1; E4F1; ELK4; SOX10; FOXO1; PHF8; RYBP; SSRP1; MLXIPL; SAFB; ZFP36L1; PCGF1; CDK2; THRA; ZNF304; TDP2; BCL3; SOX9; MED1; KLF7; SIN3B; ZNF239; REXO4; HIPK2; ZNF787; KLF12; KAT8; EWSR1; ZNF574; RNF10; SUZ12; SMARCC1; TERF2; ASH2L; RELA; RNF6; SNW1; MXI1; ZNF135; NFIX; CNOT1; ATF6; HDAC3; CIC; ZNF587; ZNF91; ZNF816; RFC1; MSL3; MEF2A; WWC1; SETD2; TFE3; DNAJC2; STAT6; ZNF205; ZBTB24; MED24; ZNF143; ZNF528; ZNF177; CUX1; FOXN2; ZBTB17; PLAGL2; TAF7; THAP11; TLE2; MMS19; MEIS2; RERE; ZNF136; SIX2; E2F5; TCF12; SMARCA4; BRD8; HIF3A; ARID5A; ZNF571; ZNF593; HDAC7; MAML1; ZBED2; CCNC; HSF1; THAP10; ZNF701; LOXL2; ERBB2; ZNF83; PREB; CBX4; NKX3-2; CHD8; NFE2L2; NONO; SAFB2; TDRD3; PCGF2; ZNF468; CRK; BTAF1; SMAD3; HCFC2; PPARD; ZMYND11; CITED1; BNC2; POLR2A; MYNN; ETS1; PKNOX2; FEZF2; ZBED1; MAGED1; ARHGAP35; SUB1; ZNF358; SMARCC2; ZNF112; SUPT3H; HOXA7; EHF; RBFOX2; TRRAP; ZBTB1; ZIC1; COPS2; HOXB2; RBBP7; CREB1; VDR; CLOCK; RBL2; BAZ1B; ZNF133; ID3; PDLIM1; CCDC59; HIC2; CERS6; FOSL2; CHD1; CTR9; HMGB2; ATF4; PRKDC; UBE2I; SMAD2; PUF60; ZNF512B; RCOR1; CTNNB1; TCF7L1; TCF20; ZZZ3; TMF1; YWHAB; FOXO4; PMF1; MTF2; ZNF654; PTTG1; PSPC1; TCEB2; PBX1; BRD4; TFEB; ELK3; PCGF3; DNMT1; HIRA; EMX2; MED17; PAXBP1; SP100; CRY1; GATA6; TCERG1; RRN3; TRIM22; TSG101; WT1; BRF2; HDAC2; ID2; ZNF692; PLAGL1; ZNF532; NFIL3; GCFC2; LEF1; ZFHX4; HIPK3; ZNF432; TSC22D2; NR4A3; GLI3; TFCP2; ZNF23; NRBF2; TOX; SP140L; PFDN5; BBX; ZNF140; ZNF586; HIF1A; ZNF274; ATN1; UBE2L3; ING4; AHR; KDM5D; VPS72; SOX17; BLZF1; ZNF430; ZNF611; JUND; ZSCAN31; AIP; TFAP2C; RBM39; SOX4; LIN28A; FOS; CBX5; TRIM28; CREB5; PIR; LPIN2; POU2AF1; TRPS1; SMARCD2; MECOM; NFATC3; MSX1; RARG; RUNX3; ZNF354A; ENY2; SAP18; TRIM16; CNOT2; TOB1; ZNF394; ZNF43; IRF7; EZH2; ESR1; KLF11; NFE2L1; PCBD1; RUNX1; HOXD1; FOXD1; CTBP2; IRF9; ZHX2; NFIB; HOXB6
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