Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57864	Biib-021	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	453	E2F2; GATA2; DACH1; BRCA1; SUV39H1; ZNF180; GCM1; WNT4; KLF4; RFX1; WDHD1; ZNF165; AIRE; SPIB; POU3F3; YEATS4; E2F8; HIC1; SOX21; ZNF211; ZNF143; BRCA2; ZNF222; NR5A2; GSC2; LMO1; PRDM10; TXNIP; CHAF1B; FOXH1; ZNF304; ATF6B; ZNF217; RELB; BRIP1; ZNF177; FOXD3; EPAS1; ZNF234; ATOH1; TCF21; PROX1; EP300; NPAT; ZNF493; ZSCAN2; ZNF225; CAMTA1; ZSCAN12; ZFHX3; ZNF45; ZSCAN16; ZFP69B; TAF1A; FOXN1; SCRT1; SRCAP; CREBZF; FOXD2; HMG20A; SOX18; ID1; PROP1; NR0B2; GCM2; ZSCAN9; ZNF550; OVOL2; CEBPA; MECP2; ESRRA; ZNF362; ZNF3; POU4F3; ZNF443; WWP1; JAK2; ASCL2; ZBTB25; MED6; DOT1L; E2F1; NR1I2; ZNF419; ZBTB3; ZNF480; AGO2; LHX3; SUV39H2; MAPK8IP1; HINFP; CSDC2; ZNF331; ZNF250; PML; ZNF573; ARID3A; EHMT1; NEUROG2; NFIC; SIX6; ZNF219; HOXD12; ZNF473; THAP7; MAML1; NUP62; ZNF613; ETS2; ZNF248; ZNF440; NR3C2; ZNF696; PAX2; NFRKB; NFKBIB; ASCL1; MYCL; HIVEP2; LHX1; POU2F2; PRDM1; ZFP64; MLLT1; NR5A1; ZNF292; TRIM24; MDM4; ZNF227; BRWD1; ZNF623; KLF13; ZFY; TBX4; MGA; HOXA7; LBX1; TCF15; AFF2; PEX2; MLLT10; SOX11; ZNF551; NR6A1; RBL1; TADA2A; FOXJ1; TLX2; MZF1; HOXD3; MED14; POU6F2; ZNF749; HOXA6; ZNF174; CENPB; CBX4; TSHZ2; ZSCAN31; WHSC1; NKX2-5; LITAF; KMT2A; ZBTB44; NEUROG3; ENO1; SETDB1; MAP3K10; ZFP36L2; MED17; ZFP2; ZNF516; ISL1; HOXB8; MYOD1; INSM1; ZNF343; ZNF41; PITX3; MAFK; ZNF7; SKIL; TEF; ZNF236; ZNF184; TBL1XR1; MAFG; PRMT2; SMAD7; SOX4; SOX1; ZNF446; CBX2; MLXIP; THAP9; HNF4G; NKX2-1; VHL; SMARCA2; POU2F3; ZNF770; POU1F1; PKNOX1; SPI1; STAT5B; ELF4; ZNF254; E2F4; ZNF34; SOHLH2; KLF10; CBX7; PGR; MYBL2; MAK; ZNF510; EYA1; ZNF10; TAL1; POLR3F; HOXB9; SUPT6H; RFX2; ONECUT2; FOXJ2; ZNF384; POU4F1; PPARG; EMX1; TFE3; ZNF141; OVOL1; PRDM13; HOXD9; PNRC1; TOPORS; FOXA2; UBE3A; CDX1; ZSCAN5A; CDX2; ZNF410; LHX6; ZNF764; AHR; POU2F1; TBX3; CARF; CNBP; RXRA; ZNF112; MECOM; DAXX; SKI; ID3; ZBTB7A; SRY; BPTF; HOXA3; ZNF391; MED1; TLX1; ZNF74; TBP; PRDM14; ZNF345; ACTL6B; PAX8; ZNF557; MYCN; ATF3; PRDM5; ZNF711; ZNF813; JUP; MKL1; NFATC3; ZFX; HNRNPD; MEOX2; PLAG1; DBP; ERF; GATA4; VGLL1; ZNF202; CHD2; ZNF134; CEBPE; KDM4C; ARNTL2; ZBTB32; SNAPC4; HMGB3; TBX1; NPM1; ZBTB40; ARRB1; ZNF556; MKL2; ZSCAN32; ZNF606; ZNF131; NR2F6; ZNF75D; MNX1; ZNF442; JUNB; ZBTB48; NR2F1; ZKSCAN5; VDR; MEN1; FHL5; MNAT1; EGR4; IRF6; TTF2; NRBF2; NFYA; KLF3; ZNF107; ZBTB11; IRF5; PHIP; NFYB; SNAI1; BCL11B; PHOX2A; ZBTB6; ZBTB7B; CBFA2T2; SCAI; NFE2; FOXN3; ANKRD1; ZBED1; HOXA10; BCL10; STAT4; ZNF682; NR1D2; FEV; SMAD5; HNF1B; RNF111; MEF2C; PAWR; HLF; ZNF787; GATA1; RNF138; IRF4; POU2AF1; ATF1; EGR2; NPAS1; HMBOX1; EGR1; MYT1L; ZNF423; BAZ2A; ZEB1; MYB; SIX1; NFX1; PITX2; EGR3; RNF14; CIC; RCOR1; CENPF; C1D; GLI1; ABL1; ZNF8; HSF4; ZBTB20; PTRF; TLX3; MEOX1; HLX; E2F5; FOXI1; ZNF667; CHD7; ELF3; SSX1; ASXL1; ACTL6A; HOXD1; TAF4B; GFI1; BLZF1; FLI1; GABPA; NR4A1; TERF1; KMT2D; ARID4B; WWTR1; RAD21; ZNF175; PLAGL1; KDM5A; CBL; BACH1; ARHGAP35; HOXA1; ZMIZ1; NR4A2; MEIS1; ZNF232; FLNA; AFF1; PURA; PLAGL2; CHD3; FOS; GFI1B; SMAD6; EYA2; ZXDC; TAF9B; SMAD1; BLM; NCOA2; MNDA; TCF7; YWHAB; FOXF2; HOXC8; RFX5; CBFA2T3; SFPQ; TDP2; FOXF1; FOXL2; PEG3; SOX17; JARID2; FOXG1; BASP1; KDM5D; FOXC1; ZNF264; HOXA5; TFAP2C; BTG1; CREB1; TCEA2; SNAI2; ZNF586
Down-regulation	410	VGLL4; GTF3A; CEBPB; TCF25; DNAJC2; HCFC1; CRK; MYC; BRD7; MED13; HBP1; PA2G4; CEBPG; CSDE1; TCEB2; NOC2L; DRAP1; ZNF281; MBD2; TGFB1; ZMYND8; HTATIP2; TRIM22; SUPT4H1; TWIST1; SND1; MAX; THAP4; WIZ; RLF; SMARCB1; UBP1; KAT8; HOXB2; RHOA; CDK7; CDK9; CTBP1; NAB2; MNT; NFYC; COPS5; SOX9; NFAT5; BHLHE41; SPEN; EDF1; TGFB1I1; RBBP7; MED21; SAFB2; MLX; GATAD2A; TAF10; CERS4; JUND; YBX3; FOXK2; SMARCD3; HIRA; RNF4; ZNF593; ZNF76; ITGB3BP; DPF2; STAT6; E4F1; NCOR2; BANP; ALX1; MYBL1; CBFB; UBE2I; SF1; SP140L; TSG101; ZNF580; GTF2A1; RARA; MDFI; MTF1; RNF141; EWSR1; ZHX2; CTCF; CCDC59; RFXANK; HMGXB4; POLR3C; TDRD3; PHF1; HMGN3; CREB3L2; SMARCE1; MED27; RBBP4; PPRC1; NSD1; NFE2L3; HIVEP3; NFKBIA; HMG20B; TOX4; MYRF; HOXB3; TRAK1; ZNF589; RELA; ARID5B; TAF5L; HDAC5; NR2C1; PMS1; PEX14; ASH2L; ETV1; THRAP3; MMS19; FOXD1; HMGA1; CREB3L1; MAGED1; PFDN5; BCL6; CAMTA2; CIZ1; RUNX3; ZFPM2; GMEB2; SOX12; CDK2; HDAC2; ZNF816; YEATS2; THAP10; RRN3; ZBTB17; FOXO3; NFIX; XBP1; CCNH; NR2F2; POU3F2; CREB5; CREB3; RFC1; TLE1; MED24; PARP1; SERTAD2; CALCOCO1; TSC22D3; GLI3; TEAD4; USF2; IRF2; PKNOX2; LOXL2; HEY1; CDC5L; SAFB; CITED2; GTF2A2; MED12; PMF1; ZNF302; TFDP1; ZIC1; ERCC3; NELFB; SUMO1; MXI1; CLOCK; KDM5B; TRIM27; THRA; TCERG1; RERE; SCMH1; SMARCA5; EN1; PDLIM1; MTDH; FOXO1; MYCBP; CTNNB1; HOXB6; ZNF91; KLF7; IFI16; ZIC3; TRIP6; EHMT2; TAF6; DR1; CITED1; TAF7; ZNF205; YAP1; SUPT3H; AIP; SIN3B; SUPT5H; KAT7; HMGXB3; TP53; SMARCC1; ZNF692; VAX2; BNC2; MAFF; CRYM; ZNF44; HIF3A; ZBTB24; OLIG2; SAP130; SMAD3; HIPK2; SAP30; DDX54; ECD; SP3; SOX2; HOXB7; HDAC7; CBX5; ATF5; PSIP1; HDAC1; ZNF528; CUX1; BRF2; MSX1; MAZ; MEF2D; PTTG1; SSBP2; POLR2A; SPDEF; ZBTB18; PSMD9; ZMIZ2; FOSB; ZNF611; TCF3; RBM39; NFIL3; DEAF1; TGIF1; SREBF2; PBX1; ZNF195; MED23; SMARCA4; CCNC; XRCC6; MAF; TBX21; HDAC6; SETD2; COPS2; HES1; HMGB2; ZBTB16; NCOA3; SUZ12; KLF9; SAP18; ESR1; SP100; TCEA1; IKBKAP; ZNF432; TADA3; FUBP1; ZNF35; CERS6; HOXC6; ZZZ3; PIAS2; YAF2; ZFP36L1; NR0B1; SIRT2; NPAS2; RNF10; SHOX2; SUPT7L; RBPMS; ZBTB38; CNOT2; LDB1; TFAP2A; DNAJC1; TBPL1; ARNTL; TEAD3; MED4; PRKDC; NAB1; RSF1; KAT5; SLC2A4RG; WT1; PCGF3; ZNF268; TEAD1; NCOA4; TFEB; SMARCD2; CTR9; ZNF23; RB1; TFAM; GTF2IRD1; SIRT7; KAT2B; TCF7L1; PCGF1; ARID1A; RXRB; TRPS1; LPIN2; STAT3; PRRX1; PHF8; ZEB2; KMT5A; ZNF394; HDAC9; CEBPZ; PSPC1; PHF20; PREB; DDIT3; ZMYM2; RBBP5; CDK8; E2F6; RUVBL2; SUB1; RUNX1; SMARCA1; ING2; BRD8; ZNF12; ZNF430; TAF1D; PUF60; KAT6A; LIN28A; REST; TSC22D2; ERBB2; NFKB1; TULP4; BIRC2; THAP11; ID2; GLI2; CTBP2; SOX10; SOX13; RBFOX2; BCL3; ZNF136; PAX5; KAT6B; ZNF512B; GMNN; TCF7L2; RAN; CREM; SP110; PPARD; ZNF239; RBBP8; NFATC4; BAZ1B; RREB1; EMX2; ZNF544; FOSL1; TSC22D1; FOXA1; MEIS2; KLF2; RBPJ; NRIP1; MEF2A; ZNF415; SREBF1; JUN; ZNF468; USP22; SATB2; LEF1; NR1H3; MITF; BRD4; URI1; ID4; TRIM16; MTF2; ETV5; EHF; NFIB; TFEC; MAFB