Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57862	Plx-4720	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	365	E2F2; DACH1; SUV39H1; GATA2; PIAS1; TCFL5; CBX7; PAX8; IKZF1; ZNF248; POU2F1; ZNF189; TXNIP; ZSCAN16; RXRG; FHL5; TAF7L; ARNTL2; YBX2; DMRT1; SOX15; LHX6; CDX1; NKX2-5; MYBL2; ZNF493; SOX13; SFMBT1; ARID3A; MAPK8IP1; ZNF180; KLF4; ZBTB43; HNF1A; FOXH1; E2F1; PRDM10; ATF3; BRCA1; PKNOX1; CARHSP1; NR5A2; SOX21; ACTL6B; HIC2; ZNF143; ZNF14; HNF4A; ARID3B; NPM1; OVOL1; ZNF443; CCNE1; NLK; EPAS1; MEOX2; PHIP; ZNF219; TRIM24; LYL1; ING1; PRDM1; ZNF473; MNDA; KLF2; HOXD3; ZBTB44; CEBPA; RBPMS; TBX21; ZNF710; EGR2; MAP3K10; PRDM5; ZNF324; NFYB; FOXN3; KLF5; ZNF507; TBP; PROX1; OSR2; LITAF; TLX2; ZNF423; ZNF536; TLE4; PRRX1; MBD1; NR4A1; ZNF112; LEF1; PAX1; ZBTB25; NR2F2; FOXJ2; KLF15; HMGA1; ZNF614; MNX1; ZNF446; GMEB1; GATA6; PAX7; ZBTB20; ZFP36L2; ZMIZ2; TAL1; WWP1; FOXJ3; WWTR1; MED14; CIR1; HNF4G; MXD1; TAF1A; RFX2; PRMT2; LHX3; ETV6; FOXE3; TFDP2; PPARGC1A; ZSCAN5A; PPARG; ETV1; HOXD9; CHD2; ZNF292; ASCL3; BCL11B; POU5F1B; KLF1; MBD4; ZNF75D; UIMC1; MED1; ZNF324B; EZH1; KLF3; RNF4; PAWR; PHOX2B; TFDP3; GATA1; ZSCAN12; RNF14; ZNF384; CEBPZ; STAT5A; ZNF22; ING4; NRL; CRTC1; ZNF442; TBX3; NRF1; SMAD9; IRF5; SALL1; CSDC2; ZIM2; SSX3; MED7; MEOX1; TCF21; HAND1; CREB3L1; BARX2; HOXD1; STAT5B; MECP2; ACTL6A; ZNF337; TOPORS; NR1H3; JAK2; ENO1; ZKSCAN7; NEUROD1; FOS; CREBZF; ZNF235; TRIP4; ZNF813; SIX3; HLF; ZNF672; MED6; MEIS1; NR3C1; ZSCAN9; TCF7; HOXC11; BRCA2; IRF6; ZNF350; MXD3; TTF2; CLOCK; RERE; ETV4; EP300; GATA4; JUNB; CAPN15; ZNF165; ZNF211; PRDM12; SMAD6; MAFG; FEV; NR1I3; E2F8; ISL1; WHSC1; PBX2; ZNF510; MECOM; NEUROD2; ZNF236; ZNF222; ZNF45; MTF2; NEUROD4; SIX6; ZNF184; TP63; VGLL1; ZNF266; SPEN; ZNF557; ORC2; IRF3; ZNF552; NPAS2; ELF2; SSX1; CBFA2T2; GABPA; NEUROG2; THAP10; CHD7; BHLHE41; CBL; NFE2; EP400; NR1I2; GATA3; HOXB13; POU6F1; GFI1B; SOX10; HMG20A; ETV3; NFRKB; ZBTB40; SOX3; EGR4; SETD3; TAF4; TRAF6; PHOX2A; SRY; C1D; NFKB2; ZXDC; INSM1; NR3C2; ZNF175; GABPB1; ZNF84; ZNF721; ZNF253; STAT4; RBL1; UBE3A; EGR1; CHD1; FOXG1; INSR; HSF2; TAF12; BRPF1; BACH1; ZMYND8; ID4; SPIB; TRIM29; CBX3; ERG; CDX2; SOHLH2; AGO2; NCOA6; CDK8; BATF3; MAK; BRIP1; AHR; ETV5; CD3D; FOXF1; FOXE1; ZEB2; SSBP2; SFPQ; HOXC8; NR4A2; ETS2; BLM; ID1; TFAP2C; NR2F1; KAT2B; FOXA2; ZNF226; KAT7; GFI1; NR1D2; ZNF33B; FOXC1; ZFX; ASCL1; DLX4; CREG1; ZSCAN32; PURA; LIMD1; EYA2; ZNF408; PREB; CEBPD; TFEC; AFF1; ATF1; CHD3; ING3; MTA1; ELF3; BASP1; BCL11A; MYRF; PAX6; EMX2; NFX1; IRF8; MTA2; RREB1; FOSB; ZZZ3; BTG1; TBX2; DDIT3; CREM; SAP30; JARID2; SNAI2; FOXF2; SOX17; PBX1; MYB; SSBP3; FHL2; EGR3
Down-regulation	443	RHOA; TRIB3; MED13; COPS5; TCF25; HMG20B; ZNF281; NFYA; CRK; GTF2F1; HTATIP2; MAZ; SMARCD3; SP3; DRAP1; HCFC1; FOXO3; HIF1A; WIZ; LOXL2; ZSCAN18; CTCF; DPF2; RFXANK; MBD2; EHMT2; HOXB3; EVX1; NFIC; SOX12; SF1; MXI1; RBBP8; VEZF1; SMARCC1; RUVBL1; PUF60; FOXK2; BACH2; TEAD1; TWIST1; CCNH; HMX1; ZNF544; HDAC5; DEAF1; SREBF1; HSBP1; RBBP4; CIZ1; ZKSCAN1; ZNF668; PRPF6; PRKDC; CTR9; SIRT2; TCF4; ZNF358; HSF1; ZNF665; TBPL1; ZNF195; HBP1; PPARD; ZNF574; MTDH; PARP1; ITGB3BP; CHD8; TGFB1; SAFB; ERCC2; APBB1; RELA; CHD4; XBP1; CBFB; ZNF205; ATF6; SUMO1; TSC22D4; KAT2A; BRD7; NOCT; ZFP36L1; RING1; RBPJ; YEATS2; RNF138; MED12; ZNF646; CEBPG; ZNF444; ZNF580; JUND; NFIX; RNF2; ZNF91; BIRC2; NFAT5; THRAP3; SSRP1; TLE2; E2F3; ZNF562; BCL3; RLF; TSG101; TEAD3; SMAD2; TONSL; MYC; ZBED2; NFE2L2; HDAC7; MEF2D; KLF13; ZNF587; TCEB2; ZNF133; PPRC1; NELFB; TCF3; THAP4; ARID4B; CDK9; WWC1; TRPS1; FOXO4; NCOA3; SUPT7L; ZHX2; E4F1; HOXB2; TFAP2A; MYBBP1A; MLXIPL; BRD3; ZFHX4; GTF2A1; XRCC6; GLI3; GLI2; TRIP6; ZNF32; STAT6; CDK2; ATF5; TULP3; MED24; MYOG; BANP; TRIM27; RUNX3; MED27; TDRD3; CAMTA2; ZBTB24; POU3F2; SMARCA5; PSIP1; MEF2C; CCDC59; AATF; PBX3; NFE2L1; PRDM4; HDGF; GCFC2; MEN1; KAT8; SIX5; REPIN1; SMARCA1; TEAD4; SIX1; ARID1A; MDFI; ZNF692; VAX2; IRF7; PIAS3; ZNF24; YAP1; NAB2; CNBP; MED20; TCERG1; NONO; SUPT3H; ZNF274; ZNF224; SIX2; PMS1; HOXA4; TCF15; PKNOX2; CDC5L; NSD1; ZNF329; MAX; SUPT5H; SREBF2; ABL1; ZNF232; ZNF117; ZNF76; RBFOX2; MED15; TGIF1; ZNF264; ZNF273; HOXA5; BARX1; HIRA; ZNF131; ZNF239; TBX1; NFATC4; MDM2; ZNF44; RXRB; NFKBIA; PFDN5; DR1; EDF1; IRF2; ZNF12; BRD8; TSHZ2; NFYC; PBRM1; ZNF135; PSMD9; ZNF410; TOX; SMARCD2; ARHGAP35; ZNF43; ETV7; PEG3; CREB3L2; MAF; HABP4; NCOR1; HDAC2; POU2AF1; SP140L; HOXA10; ZNF430; TAF7; GTF2IRD1; NCOA2; MYF5; THAP11; STAT2; MAGED1; ZNF576; SMARCC2; ZBTB7A; KAT5; TAF6; MXD4; HOXB6; SERTAD2; VGLL4; ZNF593; FOXN2; PLAGL1; BRD2; NR2C1; HMGXB3; BRD4; CIC; SMARCB1; UBE2L3; DNAJC1; BCL10; L3MBTL1; AR; HOXA7; PCBD1; BNC2; FEZF2; TFCP2; CTNNB1; PHF1; CCNC; ZNF512B; SNW1; UBTF; RBM39; CREB5; MSL3; HIPK2; TGFB1I1; ADRB2; CHD9; HDAC3; HEY1; CARM1; ILF2; LDB1; PIAS4; UBE2I; MYCBP; PCGF1; GTF2I; EN1; TERF2; ZIC1; TCF7L1; SOX4; FLI1; ZNF394; KDM4C; MED16; ENY2; KAT6A; CCNA2; MNT; AES; ZNF573; ZNF74; DMTF1; SUZ12; ZNF426; ZNF148; PSMC3; PCGF2; HDAC1; CSDE1; ZBTB1; ARID5A; CNOT2; NR1H2; NFATC1; ZNF768; HMGA2; TCF12; PITX1; SP100; IKBKAP; E2F5; CEBPE; RBM14; POLR3C; TRRAP; HIVEP2; TERF1; KMT2A; ZNF23; DEK; SATB2; CBX4; ID3; ASH2L; SP110; MNAT1; MITF; BAZ1A; ERBB4; FOXO1; CTBP1; VDR; ARNT; CUX1; HMBOX1; MMS19; NFIL3; PEX2; CERS6; SHOX2; KLF6; GTF3A; NAB1; TRAK1; ATF4; MED17; ZBTB17; HHEX; WT1; SND1; ZNF586; RUNX1; SMARCE1; PMF1; ST18; GATAD2A; RUVBL2; NKX2-2; HOXC10; ZBTB16; MEF2A; MEIS2; RNF10; NFKB1; FOXA1; HMGB1; ADNP2; PHF20; GTF2A2; SIRT7; ESR1; TBL1X; RARG; SP140; ZNF415; OLIG2; ID2; NFATC3; ELK3; RB1; ZNF611; ZMYM2; KDM5D; BAZ1B; ETS1; USP22; NCOR2; KDM5A; APEX1; TCEA2; PSPC1; TRIM22; PDLIM1; CDK7; C1QBP; ZNF83; FOXD1; NFIB; CTBP2; TSC22D1; TOX3; HMGB3; HOXB7; CREB1; HOXC6; TSC22D3; SPDEF; TRIM16; VPS72; DNMT1