Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57854	Saracatinib	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	SMARCC1; SETDB1; MKL2; CNOT1; TAF9; ZIC3; ZNF273; SMAD1; BRD7; CSDE1; ZEB1; MSC; EMX2; VPS72; DNMT3B; SIX3; SMARCA1; TERF1; PAX6; CAMTA1; RORA; SHOX2; FOXO4; TTF2; FOXN3; PCGF3; MYRF; PEX2; NANOG; TWIST1; LIN28A; ARID5B; CREM; NCOA2; ZNF117; ILF2; SLC2A4RG; NR1H4; UBE2L3; INSM1; ZFHX4; SREBF1; DMTF1; TCEA2; SPDEF; INSR; HLF; GTF3A; SREBF2; SATB2; KLF6; CRYM; PBXIP1; PLAGL1; ZNF711; BNC2; AR; CREG1; RFXANK; BACH2; ZNF107; FOXG1; PBX1; CEBPD; TDP2; NFE2L2; RAD21; MYCL; SMAD3; AES; PFDN5; JUP; EYA1; HMGB1; FOXF2; IRF9; LEF1; TLE1; WT1; HOXA10; ZNF91; KLF11; ATF5; MSX1; ST18; SOX9; RBFOX2; MTA1; DDX17; HOXC10; URI1; TFDP2; PDLIM1; SUB1; NR2F6; TOX3; MAGED1; AEBP1; MYB
Down-regulation	137	NR2F2; ZNF45; ELK3; MBD2; MAFB; RCOR3; PTRF; ZNF143; ELF5; THAP11; ZNF148; AHR; ORC2; KLF10; BRD2; ING2; BCL10; ZNF14; EGR3; DNMT1; FOXC1; HNRNPD; SPIB; ZSCAN16; ZBTB43; MLX; JAK2; ZBED2; TAF10; ZMYND8; TSC22D3; ELF4; ZNF304; PTTG1; CTBP2; CTR9; WWTR1; ESR1; SAP130; ZNF329; SFPQ; TOX; RBPMS; ZNF84; TRIM22; ZBTB11; GABPB1; HMGA2; BMI1; SMAD7; RNF138; ATF1; TRAF6; ZNF443; HMGA1; MYNN; TBPL1; CENPF; BHLHE41; ADNP; ING3; GMNN; YAF2; TRPS1; MYCBP; VDR; TGFB1I1; ZNF426; NFAT5; MEF2A; NFIB; BASP1; TOPORS; ZNF587; FOSB; ESRRG; NR4A2; MEOX2; EYA2; RNF111; FOSL1; CHD3; IKZF5; ARNTL; TFCP2L1; RRN3; ZNF134; RBBP5; RUVBL2; TRIM32; CITED2; HHEX; ZNF557; LYL1; MECOM; EZH2; EGR2; ZNF200; ECD; SMARCE1; BAZ1A; EGR1; NCOR2; AGO2; NR4A1; PURA; PAX5; PATZ1; MEF2C; BRPF1; CBFB; ERG; ZBTB16; ZNF432; LPIN2; ZNF175; FHL2; KAT2B; C1QBP; SIX1; FOS; NR1H3; KLF2; ZBTB18; HMGB2; EHF; MEIS1; SOX17; CREB1; MTF2; RUNX1; TBX2; TFEC; KDM5D; NR3C1; ZNF586; ID4