Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57849	Buthionine-sulfoximine	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	407	TCFL5; RELB; IKZF1; DACH1; ING1; STAT5B; ZNF124; E2F2; PAX8; ZSCAN16; EED; ZNF180; ZNF3; SKI; SUV39H1; CASZ1; ZNF510; SETDB1; ZNF189; RFX2; ZNF184; ESR1; ZNF45; TLX2; GATA3; IRF6; E2F1; ZNF672; REPIN1; ZNF446; HNF4A; SMAD7; GATA1; PBX2; MEOX1; PAX1; KMT2B; CREBZF; ZNF671; FOXN3; ZNF551; EGR2; POU2F2; HOXD13; OVOL1; ZNF282; CIITA; HNF1A; ZNF419; NFE2; AFF2; ZNF281; EP300; SPIB; CAPN15; KLF13; NFAT5; ZBTB43; ZNF493; FOXJ3; HOXC4; NFKBIB; PROX1; ZNF443; ZSCAN2; ZNF248; OLIG2; PML; ZSCAN9; MLLT10; ARID3A; NR0B2; SOX2; MBD1; ORC2; MZF1; HEY2; BRCA1; FOXJ1; AIRE; EGR3; MNAT1; ZNF606; EP400; MYB; ZNF24; LYL1; ZNF177; PBXIP1; ZNF263; BMI1; ZNF467; EN2; HDAC4; ZNF222; DOT1L; PRRX1; NEUROD2; STAT5A; ZIM2; ZNF211; SIX6; SIAH2; KDM5A; ST18; CHD2; MEOX2; PPARGC1A; HDAC11; ESRRA; TBL1XR1; RBBP5; DYRK1B; CHD3; KLF1; HIVEP1; PAX7; CHD4; ETV6; ZFHX3; ZNF423; MDM4; ZSCAN18; LMCD1; NR1H3; ZNF764; ING3; PATZ1; NEUROD1; TRIM24; SOX5; PRDM8; BPTF; ZNF212; ZNF324; ZNF75D; NR5A1; VDR; HIPK3; SNAPC4; HIVEP3; ZNF112; NR4A2; SFMBT1; CBX7; NFATC1; ZNF384; LHX1; TBP; MNDA; ZNF778; JAK2; RFX1; CERS4; KDM4A; ESRRB; CDX1; ASXL1; ZNF14; HLF; ERF; SOX11; RXRG; NR3C1; TERF2; MECOM; TAL1; NPAT; BCOR; ZNF219; ZHX3; YAF2; ELF4; HOXB8; LIMD1; CBFA2T3; CHD7; HNF4G; MNX1; ADNP2; PGR; ZNF550; ZNF174; CEBPZ; CBL; JUP; TFEB; ZNF84; ZNF165; NCOA1; ZNF267; ZNF696; ZNF227; NHLH1; LHX6; CEBPA; LHX3; ZNF586; HR; SMAD2; FLI1; SOX21; NFKB1; ZSCAN31; BRD2; FOXJ2; NR2E1; FOXA1; ELK3; CCNT1; ZNF506; DNAJC1; BRCA2; CENPF; KLF2; IRF5; RNF14; IRF4; MED1; BHLHE40; OVOL2; YBX2; STAT2; TGFB1I1; TAF1; MBD3; HOXC5; CHAF1B; ZNF536; IRF1; MYOD1; EYA2; ARNTL2; ZNF239; ZNF131; NRBF2; ZNF22; ZNF135; ZNF500; ZNF16; ZBTB44; SNAI1; ZNF107; SMARCA2; ZNF408; TRIM25; ELF2; USP16; TBX2; KLF9; NFATC3; MTF2; CREB5; NKRF; NCOR2; GON4L; CD3D; CCNA2; ZBTB32; ZNF768; MYBL2; DBP; TBX3; NRL; TRIM32; HDAC7; FLNA; MEIS1; CENPB; ETV3; TOPORS; KAT6B; ZNF134; SSX3; ZNF8; HSF4; ZNF343; NFKB2; SATB2; OSR2; TAF10; MBD2; ATF1; ZSCAN32; MBD4; POU2F1; FUBP1; HOXB13; TLE4; GFI1; TFCP2L1; ZNF257; EMX1; ZNF629; ZBTB48; TAF1C; SOX13; WHSC1; TFDP2; TRIM28; ZNF345; WT1; CARHSP1; CREB3L1; HOXD3; HCFC2; BCL11B; BRWD1; UBE3A; PRDM1; BARX2; CIR1; BCL3; PEX2; VPS72; EPAS1; NLK; CIC; ING4; MAP3K10; CCNE1; JUNB; ZNF787; ZBTB7B; E2F4; TFAM; ZBTB25; EGR1; NR3C2; PAX5; EGR4; TCF21; SNIP1; CCNC; TAF1D; ZBTB20; NCOA6; ERBB4; ETS2; TXNIP; TAF9B; BLM; FEV; FOXA2; ZNF200; LHX2; PHOX2B; RUNX1; ZNF415; POU4F1; NKX2-2; ZNF7; BHLHE41; NR4A1; SMAD1; MAK; ZBTB6; ZEB1; SP140; ASCL1; TCF12; BATF3; KLF10; ZFPM2; ERG; KMT2A; KMT2D; ETV5; ZBED2; DLX2; HOXC6; MED23; HSF2; HOXC8; HMG20A; HDAC6; BTG1; BRPF1; INSM1; SALL2; PURA; TBPL1; ZIC1; ZNF93; EZH2; IRF9; BASP1; TOX3; SIX1; GRHL2; PLAGL2; IRX5; ZNF468; IRF8; RFX5; ABL1; SATB1; SCAND1; ZNF33B; TBL1X; ADRB2; ZBTB18; MAFB; CALR; FOXG1; HMGN3; POU2AF1
Down-regulation	395	RUVBL1; RHOA; DNAJC2; PRPF6; GTF2F1; SUPT4H1; XRCC6; CREB3; VGLL4; MED13; EWSR1; TP53; PIR; UBE2B; NPM1; HTATIP2; SP3; DPF2; GTF2A1; RBBP7; COPS5; CTCF; HMG20B; TEAD1; MYC; YBX3; MDM2; SHOX2; EDF1; ENO1; ZIC3; CTBP1; DRAP1; WIZ; PIAS4; WDR77; TRIM29; FOXO3; CTBP2; TCF25; MLX; SMARCD3; GATAD2A; SETD2; MXI1; DMTF1; UBE2L3; BRD3; TWIST1; HNRNPD; CEBPG; CNBP; MED21; RNF2; NFYA; ATF2; HMGB1; BTF3; MAZ; NFIX; FOXK2; TEAD4; GMNN; CREG1; NR2F1; NFE2L2; SMARCB1; TAF6; RBFOX2; SOX15; SUMO1; E2F3; BRD7; TULP3; GABPB1; RFXANK; PSMC3IP; PEX14; TDP2; ZNF76; HBP1; YEATS4; HDGF; TCEA1; TFAP2A; KAT2A; RING1; HOXA2; RBM14; CREB3L2; DEK; MEIS2; TEAD3; MAFG; SMAD3; ARID1A; PSIP1; ZFP36L1; ZNF148; CNOT1; AHR; MYEF2; TSHZ2; ZFX; MEF2C; SMARCA1; CUX2; GTF2A2; ATF6; ZBTB38; ZNF574; TGIF1; ZNF593; ZNF331; HOXA11; ZFP69B; ZBED1; PBX3; CNOT2; HOXB6; LOXL2; ATF7IP; RXRA; KDM5D; YAP1; PPRC1; RELA; PSMD9; PBRM1; KAT8; SUZ12; BIRC2; PKNOX2; XBP1; PQBP1; TAF11; NFE2L1; RARB; CUX1; YEATS2; MDFI; BNC2; ZNF675; BTAF1; ZNF770; ZNF91; LIN28A; TFE3; NFKBIA; BANP; ZNF532; KLF5; SOX9; ITGB3BP; ZNF117; YWHAB; PLAGL1; APEX1; MNT; NR0B1; PUF60; CDC5L; HMGXB3; MYBL1; FOXF2; ZBTB24; TBX1; ZNF12; ZNF426; MED4; ZMYND8; NELFB; SMARCA5; DR1; RUNX3; TCF7L2; MMS19; ZNF528; GLI2; PAX9; VEZF1; ZNF302; MED16; HOXB5; ZNF334; SIX2; MED27; ZNF652; THAP4; SP140L; ERCC3; THAP7; SRF; TLE2; GLI3; ZNF215; SIN3B; NR2C2; SUPT7L; SMARCA4; FEZF2; RFXAP; HIC2; PTTG1; ZHX2; RYBP; PHF1; RNF10; SNAI2; AATF; HOXB2; EN1; MED12; NFYC; NCOR1; MED15; TFDP1; INSR; HOXA5; DDX5; DDIT3; MED17; HOXA4; TCF3; HOXB3; SKIL; PPP1R13L; TSC22D2; MYCBP; MEN1; RBM39; FOXC1; ELF5; SSRP1; ACTL6A; KAT6A; HDAC2; CDYL; MED20; TDRD3; ZNF274; ETS1; IRX4; NONO; SSBP2; PCGF1; NR2C1; NKX3-2; STAT6; TRIM16; HMGB3; ID3; SOX4; ZFP36L2; SAFB2; PARP1; NR2F6; TFAP2C; CRK; PDLIM1; GMEB2; VAX2; ZNF43; HLTF; BRD8; SNW1; ARID5B; SAP130; ZNF552; ADNP; CBFA2T2; SAP30; TRIP6; PITX1; HEY1; SERTAD2; EMX2; SUPT3H; SIRT7; TFCP2; CCNH; CARM1; ZNF44; NPAS2; NFIC; CBFB; TTF2; HABP4; PSMC3; CDK7; SETD3; ID2; CNOT6; EHF; EHMT2; FOS; ZNF146; SIX3; PPARD; ZNF232; ANKRD1; ZNF544; MAGED1; ID1; AES; AIP; RNF138; IFI16; ZNF430; PA2G4; LZTR1; ZNF195; TCF7L1; NANOG; TMF1; RAD21; CITED2; MITF; SMARCD2; RNF4; TRAK1; SP2; RSF1; CDK8; TCF20; RNF141; NCOA4; RUVBL2; TCERG1; ZNF394; BACH2; CTNNB1; CREBL2; BARX1; GTF2IRD1; BLZF1; CLOCK; BAZ1B; ZNF205; SREBF1; GCFC2; PHIP; RREB1; SALL1; TADA3; NR1H2; MLXIP; MXD4; RLF; HDAC9; SOHLH2; NCOA2; ISL1; RORA; AR; ERBB2; BRF2; HOXB7; HMGB2; JUND; PCBD1; REST; SPEN; MAF; HDAC1; NKX2-1; SMARCE1; ATF5; NKX3-1; GATA6; PRKDC; PBX1; FOXD1; UBE2I; E2F5; CBX3; MYRF; PMF1; ZNF512B; FOXO1; ZNF611; COPS2; ZNF32; TERF1; IRF7; MTDH; ENY2; BRD4; MED24; CREB1; TSC22D1; HOXC10; TCEA2; RAN; CERS6