Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57839	Apicidin	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	458	E2F2; DACH1; TCFL5; SUV39H1; RELB; POU4F1; ZSCAN2; SPIB; MAPK8IP1; BRCA1; BRIP1; AIRE; HLF; EP300; NR5A2; BRCA2; ZNF189; ZNF419; YBX2; NR1I2; CHAF1B; SATB2; PAX1; ZNF180; ZNF551; HNF4A; E2F1; TLX2; ZNF493; PRDM12; CREBZF; APBB1; SOX21; POU3F3; PRDM14; EHMT1; OVOL1; ZNF536; MDM4; FOXN3; CBX7; ZNF510; SMAD7; HOXD12; NLK; HOXA6; IRF4; MXD1; ORC2; CDX2; ATOH1; TBL1XR1; ZNF614; CSDC2; ZNF222; ZNF253; FOXD3; RFX1; MYB; ZNF211; ZNF711; ZNF177; KLF13; CAMTA1; HOXB1; SLC2A4RG; ZNF45; ZNF550; ZNF549; ZBTB7A; ZNF814; ZNF257; ATF6B; BRDT; HOXB9; CDX1; ZNF254; IRF5; HESX1; ZNF613; ZNF696; FOXD2; LHX2; ZNF34; HNF4G; MYBL2; DYRK1B; GSC2; EBF2; PRMT2; NR5A1; ZNF225; ZNF304; LMCD1; ZSCAN16; NPAS1; IL16; MNX1; TBR1; SETD3; SUV39H2; CEBPZ; SIX3; NFE2L3; NEUROG2; HES2; ZSCAN32; BATF; NR3C2; ZNF8; CIR1; HOXD3; ZNF165; RAX; ZNF134; PRDM8; ZNF131; PSMC3IP; PITX3; MNAT1; ZNF239; HNF1A; ZNF219; ZNF682; LHX3; CEBPE; TCF15; DNMT3B; ADNP2; MAFG; EMX1; ZNF671; ZNF236; ZNF155; ZNF281; POU2F2; SIM1; ZNF391; SCRT1; SNIP1; FOXJ3; GATA6; ARRB1; HEYL; CBX4; PAX5; NEUROG3; ELF2; SIX1; GBX2; AFF3; DAXX; GABPA; IKZF4; ZNF14; TOB1; HIC1; STAT5B; LMO1; SIX6; ZNF10; ZNF227; ZNF235; ZNF292; TBX10; THAP1; FOXP3; TONSL; TLE2; ZFP2; GATA3; CCNC; CAPN15; TAF4B; ZNF350; HIPK3; CDX4; ZNF263; ZBTB44; DOT1L; ZNF507; DMRT1; LBX1; ZNF695; ZNF234; BARX2; POU4F3; ZNF81; ZNF749; ZNF442; FOXE3; KMT5A; CRX; NR6A1; FOXH1; TBX2; MEOX2; BLM; NFRKB; EN2; LHX1; ZNF93; TULP1; ETV6; ZNF473; ZNF787; HOXC4; IKZF5; SNAPC4; NEUROG1; MAFK; DLX4; SP140; HMG20A; TLX3; ZNF124; SOX3; PPARG; TBP; PAX7; CEBPA; ZNF250; ZNF143; NKX6-1; TLX1; HNF1B; EMX2; PRDM10; ZNF623; BPTF; ZNF345; EGR4; PBX2; ZBTB7B; POU4F2; ZNF174; GMEB1; HOXB8; ZNF223; PRDM9; HOXD13; POU6F2; CHD2; MAP3K10; ANKRD1; PHOX2A; RFX2; CARF; MBD1; HEY2; POU3F4; IKBKAP; BCL11B; ZNF75D; MED14; PPARA; MTA2; FHL5; RRN3; BRWD1; MTA1; NFKBIB; ZNF552; KDM4A; NKX2-8; ZNF778; CARHSP1; SATB1; PROP1; HDAC4; RORC; LMX1B; TULP2; ZNF586; ZNF506; CBX2; HMG20B; PAX2; ARID4A; THAP9; MLLT10; SOX12; PRDM5; ETS2; LHX6; ZNF639; CHD7; ZBTB6; TRAF6; IKZF1; HOXC8; HOXD10; ZNF16; TFAP2B; ZKSCAN3; TEF; TSC22D4; MYOD1; ZNF140; MEF2D; ONECUT2; HDAC6; LEF1; ZBTB43; USP16; ARNTL2; KLF2; ARID3B; FOXN1; ZNF764; KLF15; PML; KDM2A; NEUROD2; NEUROD4; SSX3; TFCP2; TBX21; MYNN; SMAD6; PROX1; L3MBTL1; HSF2; NR2E1; JARID2; ZNF132; MNDA; PRDM1; THAP11; ZNF107; KDM5A; MED31; ZNF112; TP63; ZNF85; SRF; ZNF324B; MEOX1; WDHD1; ZBTB25; TGS1; HMGXB4; ZNF35; ZNF675; ID2; DDX5; GFI1B; ZNF423; NPAT; MYT1L; LHX5; TFAM; MYF6; ZNF768; ZBED4; ETV3; BCL3; HR; TOX; PAX8; IRX5; HSF1; ARID3A; TOPORS; ASH1L; HOXC10; SRY; SMAD1; TAF4; HOXA3; CERS6; DLX2; POU3F1; ZNF443; ZNF343; SFMBT1; TAF1A; ZNF556; VENTX; ZNF202; SKI; TOX3; GFI1; MLXIPL; ZNF200; ZEB2; BRPF1; LIMD1; PHOX2B; PIAS2; FEV; AFF1; FOXA2; RNF6; KMT2D; HOXD1; ZNF43; SMAD9; MED1; TLE4; NANOG; PATZ1; GMEB2; ZNF7; VGLL1; HDAC1; NRF1; MEF2C; CERS4; RBPMS; SOX10; GATA4; ZNF217; EGR2; HMGB3; BAZ2A; ZNF408; POU2AF1; BCOR; TAL1; ZNF226; DBP; JUP; SSBP2; WT1; RBBP5; NRBF2; KLF1; ASCL1; NKX2-1; CREB1; PRRX1; JUND; ZNF528; NKX2-2; SOX11; CREG1; CHD1; NR2F1; MAK; PLAGL1; ARID5B; HOXC6; ZNF175; ZFP36L2; VDR; ZNF33B; FOXG1; SOX9; NEUROD1; TULP4; SAP18; ZNF91; ERBB4; MTF2; FOXF2; IRF9; ERBB2
Down-regulation	440	HDGF; TULP3; TCF25; ARID1A; SSRP1; VGLL4; DNAJC2; PRPF6; CHD8; BRD7; PEX14; MYC; CREB3L2; CREB3; HOXB2; TGFB1I1; TGFB1; WIZ; HTATIP2; YBX3; GTF2F1; TRIM29; WDR77; HCFC1; EWSR1; FOXK2; CHD4; CTCF; FLNA; CAMTA2; SP3; DPF2; PIR; MBD2; NCOR2; FOXO3; ITGB3BP; NCOR1; TP53; IFI16; RBPJ; MLX; SPEN; RUVBL1; ATF6; DEK; ZNF532; RLF; CCNH; SF1; ARL2BP; MTDH; TEAD4; MED12; ZNF721; KAT8; SND1; APEX1; HNRNPD; MED24; MNT; SMARCD3; PFDN5; PPRC1; RELA; ZNF44; PSMD9; AATF; BANP; NFE2L2; YEATS2; ELK4; TRIM27; BRD8; DRAP1; RBFOX2; NR2C1; HIRA; ABT1; KMT2B; CTBP1; MMS19; ZNF232; ZNF611; TCERG1; PIAS3; TFAP2A; RFXANK; XRCC6; SMARCC1; TCF12; CIZ1; ZMYND8; HBP1; TAF6; RHOA; SP140L; ERCC3; PHF2; ZNF148; KDM5B; NPM1; NFKBIA; MAZ; TBPL1; SMARCB1; ZNF160; SIRT2; SMARCE1; AEBP1; ILF2; KAT2A; HES1; NR2F2; PKNOX2; EHMT2; CBFB; RYBP; MKL2; YBX1; SCMH1; DMTF1; TSC22D1; ETS1; ZNF665; ZNF688; HOXB6; HOXB3; HDAC5; HEY1; MEIS2; PCBD1; ZKSCAN1; HIF1A; ZHX2; TSC22D3; CSDE1; TRIM28; BCL6; COPS5; ZBED1; AIP; NPAS2; CUX1; ZNF83; SREBF1; RFC1; TAF5L; CUX2; ZFP36L1; GATA2; TOX4; MEIS1; BHLHE41; SOX17; PARP1; MAFF; ARNT2; PSIP1; KLF6; MLXIP; RBM39; SMARCA4; RNF10; ZNF589; PHF20; JUN; MYBBP1A; PREB; ENO1; VEZF1; GTF2A1; ZBTB38; ECD; ZNF331; ZBTB17; MITF; NCOA3; GLI3; SMAD4; PCGF2; PMF1; SAFB; PSMC3; MAGED1; BRD4; FOSL2; CLOCK; AES; E2F3; BNC2; ZFHX3; CNOT1; MEN1; BAZ1A; ATF5; SERTAD2; SMARCA5; REXO4; BASP1; MED16; ZSCAN18; NR1H2; CHD9; TDRD3; TEAD3; JUNB; HHEX; MAX; MYCN; KAT5; ZNF652; ZFPM2; ENY2; TRAK1; NFIX; UBTF; UIMC1; SIN3B; CXXC1; PCGF1; TDP2; PIAS4; CDK7; PTTG1; ZNF146; CBX3; DNMT1; HIVEP1; MSX1; CALCOCO1; NCOA6; ETV5; CARM1; NR2F6; MYBL1; PEG3; DDIT3; LOXL2; MYCBP; ATF1; TAF12; NFKB1; POLR2A; TSG101; SUZ12; IRF3; RNF138; UBP1; HLX; NKX3-1; OLIG2; FOSB; HDAC2; SP100; TADA3; STAT6; SUPT7L; KLF5; SP2; DDX54; AHR; E4F1; ZNF544; TFDP1; TCF20; ZNF23; ZNF24; YAP1; HMGA1; SMAD2; FUBP1; ELF1; HSBP1; CTNNB1; RXRB; GCFC2; RERE; NFIL3; CITED2; NCOA4; SETD2; VAX2; RORA; CREM; TAF5; FOXO4; NFE2L1; ZNF136; DEAF1; ZNF576; TBX1; MAF; NAB2; PEX2; HIPK2; SMARCD2; HOXB5; TBL1X; GMNN; PBX1; GTF2A2; MTF1; ZZZ3; PHF8; TCF4; FOXO1; CITED1; KAT6A; SREBF2; HMGB1; CDC5L; TEAD1; AR; SAFB2; NONO; ZEB1; ASH2L; HDAC7; USP21; DR1; ADNP; ZHX3; THRA; NELFB; HIF3A; RING1; BCL10; TRRAP; NFIB; ZBTB24; RAD21; NR0B1; PHIP; RUNX1; BTAF1; RBM14; C1D; TRIP6; MED15; HDAC9; CDK8; TMF1; RAN; ZMYM2; YAF2; PBX3; TCF7; TRIM16; CBX5; ZNF512B; CNBP; ZNF432; SUPT3H; CTR9; ETV4; ID3; NRIP1; NFAT5; TGIF1; MED21; SIX2; ZIC1; KMT2A; NCOA2; ELF3; PUF60; ZNF264; RBBP8; TAF1D; ATF4; GLI2; DLX5; HMGB2; USP22; DNAJC1; FOXD1; BCLAF1; NR1H4; RNF111; HOXA5; SIRT7; ATN1; ADRB2; RB1; ST18; NFYB; NFKB2; PPARD; UBE2L3; TAF11; E2F6; SMAD3; SNAI2; BIRC2; CTBP2; ZNF430; PHF1; MEF2A; CDK2; FOXM1; CEBPD; XBP1; SFPQ; RBBP4; HIVEP2; ZNF274; NFE2; CCNE1; GATAD2A; FOXA1; RSF1; SOX4; REST; KAT2B; PSPC1; ID1; CNOT6; LDB1; KLF10; EYA2; C1QBP; CRY1; MYRF; TRPS1; WWTR1; KDM5D; HOXB7; TAF7; IRF7; CBFA2T3; FHL2; URI1; BCL11A; NR1H3; CALR; ZBTB16; TCEA2; ZBTB18; VPS72