Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57831	Alvocidib	GSE92742	SKB	Human	24h	10uM	EID0320

Response Information :

Types	Number	Response transcription factors
Up-regulation	138	IRF6; ELK4; ZNF219; ETV1; MYCN; HOXC4; ESR1; KLF7; ZNF85; PEX14; ZNF665; ZBTB20; LHX3; SPI1; TXNIP; E2F4; NOC2L; PAXBP1; SHOX2; SRCAP; KLF9; CALR; TWIST1; SALL2; HMGB1; ST18; CDIP1; FOXF1; TGFB1; ZNF816; MEIS2; PEG3; HHEX; ZMYND8; IKZF1; ZKSCAN3; TFAP2A; SLC2A4RG; MEOX1; TRPS1; BBX; CD3D; ZNF331; ZNF253; ZNF500; ZNF430; SOX2; SPDEF; ZNF117; SPIB; CDK2; ZNF195; SMARCA1; ZFPM2; MYBL2; PPARD; ZNF573; TCF7; GMNN; WWP1; WT1; GLI3; MYBL1; ETS1; ZNF44; THAP10; ZBED2; SSX1; IRF8; AR; GATA6; VPS72; ZNF107; NR5A2; BACH2; CBX4; BNC2; PTTG1; IRF9; TCF21; PITX1; DMTF1; ZNF611; FOXF2; HOXB2; ZNF91; DLX2; MLXIP; GTF2I; LEF1; FUBP1; PHIP; VDR; ZNF93; TAF6; ZNF43; ATN1; ZNF580; GRHL2; BCL11A; PBX3; TOX; CREB3L2; NAB2; PSMC3; PBX1; ERBB4; SOX11; PRDM1; MEIS1; ISL1; ID1; ZNF544; CEBPA; JUP; ACTL6A; EPAS1; JUN; DNMT1; NCOA3; ZNF264; TERF1; ZNF721; PARP1; HDAC9; PRRX1; ZNF268; MYRF; ZNF160; CREG1; RBFOX2; POU2AF1; CREB1; IFI16; EHF; SOX17; NR2F6; ID4
Down-regulation	224	CRK; FOXO3; NUP62; MYC; NCOA4; REPIN1; BANP; ATF4; RBBP4; ESRRA; NR2F2; VGLL4; MAFG; FOXJ3; ZNF672; ZBED4; TBL1X; BRD3; TLE1; SIAH2; PQBP1; NCOR2; COPS5; KLF6; ENO1; KLF5; ING1; RNF4; BCL10; KAT7; MED13; CNOT1; CEBPG; ZBTB11; SMAD2; ZBTB7A; MAZ; RBM14; SOX12; ING2; CCDC59; NCOA6; SMARCA2; SERTAD2; DPF2; FOXN3; HNRNPD; HTATIP2; CTR9; TADA2A; MED1; CLOCK; PATZ1; NFATC1; YWHAB; KDM2A; BRD8; BIRC2; FOXC1; ZFP64; KDM4A; PPARGC1A; TSC22D3; ZNF281; PPRC1; MAX; PURA; TOB1; NFYC; UBE2I; WWTR1; TRIM28; ANKRD1; REST; ATF5; PHF2; CREB3L1; PHF20; E2F3; YBX1; HOXA10; PIR; ZBTB1; KMT5A; RUNX3; TBP; SNW1; PCGF2; DDX5; ELK1; TBPL1; HMGA2; NRBF2; YBX3; DR1; EZH2; ADNP; RBPJ; MDFI; ELF5; LPIN2; AATF; CIZ1; ZBTB24; VEZF1; SFPQ; CBX3; FOSB; MNT; BASP1; RLF; ZNF263; ZBTB18; NFKB1; EDF1; HEY2; PRKDC; HMG20A; FLNA; RELA; SMAD3; KAT5; KLF10; TLE2; ARID4A; AFF1; RFX7; RREB1; ARID4B; PLAGL2; ABL1; RNF6; RNF138; SMARCC1; ZNF302; BATF3; LIMD1; DNAJC1; CXXC1; MEOX2; ASH2L; MEF2A; ZBED1; IL16; HOXC6; MBD2; CDK7; TRIM32; SMAD7; KDM5D; NKX3-1; ZNF7; NELFB; HCFC2; PUF60; BCLAF1; RCOR1; ZNF32; BRPF1; SIX1; SMARCA4; FOXD1; SAP30; SREBF1; BAZ1A; SIRT7; ERBB2; BMI1; HOXB7; USF2; TRIP6; BCOR; CEBPZ; KLF1; PSIP1; CTBP2; MED24; ZEB2; KDM5A; CRY1; NFIB; FOSL1; USP22; HMGN3; KLF11; TCF12; ZZZ3; SIX2; RNF10; TEAD4; RAN; RB1; NFKBIA; URI1; NFE2L1; EGR3; PDLIM1; HSF2; ELK3; ERG; BRD4; SCAND1; JUND; BHLHE40; PSPC1; HDAC2; ADRB2; BCL6; PPARG; EGR2; BTG1; PLAGL1; TAF7; TSC22D2; NR3C1; DAXX; ZIC1; KLF2; RUNX1; ETS2; MAF; TFAP2C; IRF7; FHL2