Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57810	Deforolimus	GSE92742	NPC	Human	24h	10uM	EID0317

Response Information :

Types	Number	Response transcription factors
Up-regulation	233	NR1H2; ZNF274; SPDEF; CEBPD; LHX3; NFATC4; PRDM14; ZNF589; THRB; KLF15; RARG; ZNF253; JUN; RBFOX2; KLF13; ZNF235; ZNF331; GATA6; PROP1; IRF6; GATA1; ZNF816; SNAI2; JUP; TAF5L; OVOL1; ZBED2; ATOH1; CBFA2T2; PPP1R13L; ZFP36L2; ZNF667; NEUROD2; ZNF141; ATN1; KLF7; MED17; ZSCAN9; SOX21; TRIP11; ZNF623; TUB; ZNF165; TCF21; GRIP1; ZKSCAN4; SKIL; ZNF195; ILF2; MED25; ZNF224; FEZF2; BCL11A; TRPS1; KLF1; KDM5C; ETV3; ZNF665; ZNF10; ERBB4; ECD; ZNF43; ZNF33B; ZNF345; VGLL1; NR5A1; FOXA2; ZNF250; NEUROD1; ZNF223; HSF4; NR5A2; INSM1; ACTL6B; NRL; HOXA5; ZNF264; BARX1; EMX1; PKNOX2; ZNF91; ZNF85; AIRE; ZBTB16; TDP2; ZNF132; CBX4; ELF3; TBX21; PRDM10; SUPT3H; MAK; ZNF544; HDAC9; ZNF74; CBX2; EHF; POU4F3; ARL2BP; SATB2; CERS4; ZNF701; HSF1; BNC1; ZNF117; ZNF688; TP73; HOXB1; SOX18; TRIM29; HBP1; SP140L; EN1; CHD2; HOXC8; ARID5B; ZNF430; ZNF257; LDB1; JUNB; FOXK2; FUBP1; ELF4; ZNF426; ZNF444; SIX3; ZNF180; MBD1; ZHX2; POLR3C; NOCT; NHLH1; CDX1; CREM; ZBTB44; ZNF222; IRF9; CAMTA2; BNC2; SPIB; FOS; ZNF573; SRCAP; ZNF215; CAPN15; MED15; ZNF394; TBX1; WT1; E2F4; PCGF3; SMAD7; NR4A2; MED14; ARID5A; HOXD1; HLX; LZTR1; IFI16; ZNF835; SOX9; E4F1; ZXDC; BTG1; OVOL2; ZNF500; ELF5; MED12; ZNF611; IL16; ZIC3; TFAP2A; CBX7; HIRA; BACH2; ZNF93; MYBL1; HOXA4; PEX14; ZNF552; HOXB13; SPI1; RAD21; MLXIP; CEBPB; CREB3L2; GLI2; PRDM2; IRF8; TRIB3; NPAS2; NR1H4; SMARCD3; KLF11; RYBP; GFI1; CBFA2T3; ZNF124; ETS1; TP63; STAT4; PPARD; BHLHE41; ARNTL; ZNF83; KLF5; SOX10; NFE2L3; CD3D; TULP3; PAWR; ZNF211; SHOX2; TGFB1; LITAF; MNDA; FOXA1; ZNF217; ZNF12; FOXF2; ZNF44; CDK7; MYRF; ZNF551; NFE2; ZNF512B; YBX3; FOSB; MEIS2; KLF9; DLX5; TFAP2C; KLF10
Down-regulation	293	EZH2; SMARCA4; NFIL3; HMGN3; SUV39H1; PCGF2; PSMD9; PSIP1; HNRNPD; PUF60; SMAD3; TBP; MYBL2; RNF141; ZEB2; BCLAF1; DPF2; PHF2; PSMC3IP; ZBTB11; NFKBIA; HDAC1; LPIN2; USF2; PCBD1; RBBP4; NEDD8; SMARCA5; CCNA2; KAT7; BMI1; SNW1; BAZ1B; CARHSP1; ING2; ING1; ENO1; NONO; MED1; SMARCD2; SAP30; POU3F2; HOXB7; PTTG1; FOXJ3; HDAC6; TAF10; RHOA; SMARCC1; PIR; E2F6; SCMH1; HLTF; SETD3; DRAP1; KAT6A; BATF3; TAF1D; RFX5; NFYC; SALL1; UBP1; TLE4; ORC2; RCOR1; BRD8; PARP1; ATF1; PIAS2; DDX54; BRPF1; EED; DNAJC1; PHF8; THRAP3; SOX4; PATZ1; MED4; MDFI; ZNF24; EDF1; TBL1X; HSF2; NRF1; MGA; NAB1; STAT6; PBX1; CTR9; BBX; ZNF148; JARID2; HMGA2; CBX3; HSBP1; IRF2; ZNF516; PREB; EYA1; ZBED1; GABPB1; BAZ2B; NCOA6; HMGB2; CEBPZ; SPEN; MEIS1; ITGB3BP; SMARCE1; ZFP64; E2F2; PSPC1; TADA2A; STAT3; FOSL1; CARM1; HDAC7; EGR4; RBM14; YBX1; FOXN3; ZBTB24; ASH2L; TEAD1; MYCBP; CDK2; TOX; AATF; HDAC4; TSC22D2; TBL1XR1; CHD1; MTDH; ASCL1; PMF1; SMAD2; GTF2IRD1; HOXB6; ZNF177; MLX; HDAC3; ADNP2; MED23; MYCN; ZFP30; RBPMS; ELK1; NUP62; VGLL4; RNF10; ZNF672; TSC22D4; KDM2A; ZNF146; CCNC; TRIP6; ZNF410; WDHD1; RUVBL2; CBX5; CBFB; CHAF1B; HOXD11; ZNF443; ZEB1; ARID4B; ELK3; MITF; REST; FOXO3; PIAS3; HMG20A; ETV4; ID3; SMAD4; DNMT3B; ARRB1; TRIM32; DAXX; PQBP1; MSX1; BCOR; POLR2A; HAND1; TCERG1; KDM5B; MAGED1; NFE2L1; SP3; RB1; BAZ1A; CENPF; ARID4A; TCF12; ZMIZ2; ZNF292; MAX; FLNA; SIX2; TSC22D3; EP400; ZNF212; TTF1; SAP18; RBBP7; HOXC6; VEZF1; ZNF468; NFAT5; ZBTB38; ID2; SFMBT1; ETV5; ISL1; TBPL1; TGIF1; RFX7; CREB5; SP2; DDX17; RERE; BRD2; NPM1; CRY1; RBPJ; ERBB2; NRIP1; ZBTB18; URI1; TSC22D1; ZNF226; MAFB; RARA; HLF; SMARCA2; ZNF281; ING3; BRD3; CITED1; SIAH2; CCNE1; SMARCA1; GABPA; BRCA1; TRIM28; NCOA4; CTNNB1; FOXF1; FOXD1; ZNF189; NCOR2; ZFP36L1; TRIM16; HIPK3; RNF4; YAF2; ELF1; SFPQ; PITX1; RNF138; GTF3A; LOXL2; NKX3-1; KDM5A; BASP1; KLF2; YWHAB; HEY2; EGR2; IKBKAP; OSR2; EMX2; FOXO1; STAT5B; ZNF423; TOX3; ZMYM2; MEOX2; TP53; NR2F2; USP22; CRYM; WWTR1; DMTF1; SSBP2; TCEA2; EGR1; CUX1; MYCL; TCF4; SOX11; PEG3; NFKBIB