Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57784	Sitagliptin	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	NFATC4; PPARD; TP63; ZBTB20; SMAD4; RING1; TRIP6; RBBP8; ATN1; ING3; CREM; RERE; ZNF136; TFCP2L1; FOXG1; DEK; ZIC1; MEIS1; ZBTB43; ETS1; NEUROD1; HOXD1; BNC2; CARHSP1; C1QBP; ERBB2; MXD1; PLAGL1; SNAI2; ZBTB16; PPARGC1A; IRF8; NRIP1; MED1; JARID2; INSM1; NFIC; AGO2; BCL11A; TRPS1; POU5F1B; HLTF; EMX2; LIN28A; ZNF148; NFAT5; TRIM22; NR1H4; KAT2B; SATB2; TRRAP; WWTR1; PRRX1; UBP1; PFDN5; HMBOX1; ZNF532; YAP1; CCDC59; YBX1; NANOG; NFKB2; TLE4; MTF2; DNAJC2; PAX6; HEY1; DMTF1; SOX17; ZNF512B; HIRA; RNF138; ZNF331; NFIB; SALL2; CREB3L2; NR4A2; HOXD3; HMGN3; ELF5; KDM5D; USP22; TLE2; BRD2; KAT6A; SUZ12; ID4; NR2F6
Down-regulation	132	HMG20B; LOXL2; POU4F1; NR0B1; CARM1; HDAC4; NFE2L3; NR1H3; CRK; DDIT3; AR; TRIB3; ZNF32; CNOT6; HOXB6; MYB; LPIN2; ZKSCAN1; TRIM16; FOXD1; NFYA; ARNT2; SMARCA5; BCL3; KLF5; ZNF574; ERG; NKX2-1; SMAD3; HOXC13; CTCF; PPP1R13L; POU2AF1; ZNF711; MNT; TOX3; AEBP1; SIAH2; FOXE1; ERCC2; TBPL1; RUNX1; CEBPB; BRD8; IRF2; ESR1; IRF7; VDR; THAP4; BMI1; NFE2; TOX; DR1; ZNF227; ZNF195; TFAP2C; PHF20; ZNF274; DLX2; CBX4; HABP4; GFI1; EGR4; MYBL1; ZNF281; MXI1; DDX17; LITAF; KMT2A; HOXB7; DBP; TCEA2; MAFF; ZNF580; TAF9; BCL11B; TERF2; TAL1; ID2; PIAS3; TCF3; ARID1A; ZNF665; SAP30; RUNX3; PBXIP1; AHR; TXNIP; SOX9; CNOT3; MAZ; EGR1; STAT3; PITX1; TRIM28; ZNF430; DDX5; ZBTB18; ZNF544; DACH1; CDK7; FOXC1; SREBF1; IRX5; ZEB2; ATF3; CHD7; TGFB1; RARA; ETS2; PAX5; NUP62; BHLHE41; NR2F1; PCGF2; GATA6; HMGA1; DNMT1; CITED2; EGR3; HOXC6; TOB1; NFKBIB; CEBPA; FOSB; SMAD6; ZNF91; EGR2; NKX3-1; LEF1; ZNF586; FOSL1