Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57782	Zibotentan	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	102	HOXA5; HOXC10; ETV4; IKZF1; RBPMS; LHX2; TBX1; YBX1; CTR9; AFF1; POLR2A; POU5F1B; ERBB2; PATZ1; SOX21; MYBL2; TCF25; PBX3; KDM5D; SMARCA1; HOXB2; SALL1; BLM; TRIP6; FOXJ1; TRIM24; HDAC3; ETV5; SP110; CREB3L2; CREM; FOXA1; ETV1; AR; DDX17; ZNF589; PFDN5; CHD9; NR1H4; PLAGL1; TRIM28; CHD8; DMTF1; ZBED2; WWTR1; CITED1; ZNF232; SP100; CTBP2; INSR; ASCL1; RUNX3; FOXC1; LYL1; NPM1; MYCL; BNC2; HMGN3; SLC2A4RG; HHEX; PHF1; DNAJC2; TCF7; KMT2A; ZNF165; CBX6; NFATC1; STAT3; CUX2; ZBTB16; ENO1; OLIG2; NANOG; SALL2; ZMIZ2; SMARCA2; ZNF266; NUP62; CUX1; BCL11A; CEBPA; BAZ2B; ZHX2; NR2F1; HOXD1; NFE2; MYB; TP53; ZNF652; ELK3; BAZ1A; SOX9; IRF8; HIRA; FOXF1; SUZ12; ID1; TLE1; NFIB; ZMIZ1; MTA1; ID4
Down-regulation	94	BASP1; POU4F1; ADNP2; KLF5; FOSL2; ZBTB43; KLF2; RNF10; SMAD4; TSC22D2; TFE3; SUPT4H1; CALCOCO1; TBPL1; PIAS1; MEOX2; NFE2L1; ATF3; UBE2B; SMAD5; TFDP2; NR4A1; MED12; NR1D2; BCL3; ZNF12; NEUROD1; MYT1L; JUNB; MSC; AES; VGLL4; TGFB1I1; DLX5; DBP; SIAH2; HIPK1; SSBP2; MAX; SMAD3; TERF2; HLX; TEAD1; ZNF423; NFE2L2; SAP18; CHD7; FOXM1; POU2AF1; KLF11; TWIST1; LOXL2; OSR2; CENPF; NR3C2; SOX17; ZBTB18; TCF21; VDR; LMCD1; SAP30; MEIS2; GMNN; SUMO1; FOXO1; TCEA2; STAT6; MSX1; KAT6A; MBD2; EGR1; FOSB; EGR2; MECOM; TXNIP; EGR4; ZEB2; SMAD1; PEG3; NFAT5; NR4A2; USP22; SMAD6; DNMT1; EGR3; BBX; HTATIP2; HOXB7; ZFP36L1; MNDA; NFKB2; ID3; BHLHE41; ZNF586