Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57775	Plx-4720	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	HOXC10; CCNH; NFATC4; KDM5C; VPS72; HOXD1; TCEA1; HOXC11; MYBL2; CDX1; BNC1; ARID5B; CDX2; HOXB2; THAP10; CNOT3; SKIL; IRF9; RELA; SIRT2; ZNF250; SRCAP; ERF; LZTR1; CBX4; CNBP; ACTL6A; HMGB1; TP63; ZNF112; PA2G4; CALR; MECOM; ELF3; TULP3; MED15; NPM1; IRF6; SMARCB1; ZNF22; HOXC13; RAD21; ZFP36L2; ZNF74; ATN1; TRPS1; TAF4B; SUPT6H; HR; SMAD7; NKX2-1; HDAC7; TSHZ2; ZSCAN9; GRHL2; TAF5L; ZNF35; TBX1; ZNF195; PPP1R13L; RXRA; TGFB1; SOX9; ZBED2; RBM39; CERS4; TRIB3; ZNF574; RYBP; BNC2; TCF7L2; GATA6; ZNF536; SPI1; ZNF444; ZNF835; KAT5; ZEB1; PPRC1; E2F5; THAP7; BHLHE41; KLF11; ZNF623; BAZ2A; GTF2F1; DMTF1; CIC; ZNF331; CALCOCO1; ZNF557; ZBTB44; NFIB; RUNX1; TFAP2A; TFAP2C; HBP1; HOXC4; TRIP6; SND1; ZNF415; FOXF2; NCOA2; MYBL1; GTF3A; EMX2; MED21; ERBB4; HSF1; TWIST1; GMNN; SOX17; AIP; MAZ; HDAC9; HIC2; ZNF232; REL; SNAI2; CREBL2; SSBP3; DACH1; VDR; EPAS1; HOXD3; SLC2A4RG; MXI1; IFI16; MYRF; NR4A1; ETV5; SOHLH2; ASCL1; TXNIP; PRRX1; PBXIP1; KAT2B; ZIC1; ELK3; SUMO1; PSMC3; CEBPA; STAT6; IRF1; HMGA1; ZNF131; TLE2; OLIG2; PLAGL1; TRIM22; EGR1; ETV1; TP53; NFKB2; RORA; MNAT1; ID1; ZMIZ1; HOXB7; ZBTB38; WT1
Down-regulation	189	SPEN; SOX11; MYC; SIAH2; TBL1X; TBPL1; ING2; DNMT3B; ZNF329; ZNF516; HSF2; TBP; EZH2; ZBTB18; RFX7; TFEB; DR1; HMG20B; PIAS1; UIMC1; ECD; MED1; CHD1; SAP30; FOXO1; HESX1; TCF4; NR0B1; GABPB1; ING1; INSM1; SALL1; UBP1; BCLAF1; RBM14; MAGED1; RNF10; IRF4; EDF1; ELF2; TCEB2; BACH1; EP400; FOXD1; KMT5A; FOXO3; JARID2; SUPT4H1; UBE3A; MYCBP; BRD3; HIPK1; RFX5; AR; NFKB1; BRD8; CTCF; SCAND1; MSX1; CHAF1B; ZNF529; TRIM24; SMAD3; VEZF1; C1D; PSMC3IP; ZFP64; EBF2; FOXJ3; NCOA6; ZNF274; RBBP7; ZNF32; ZNF189; BATF; LIN28A; NEDD8; CRY1; PTTG1; RBBP5; POU2AF1; USP16; ZBED1; SSBP2; MYF6; HMGB2; ZBTB24; CITED2; HHEX; ZNF721; MYT1L; BRD4; WHSC1; SNIP1; SPIB; RBBP4; RLF; RARB; NR2F6; IRF7; ZIC3; SRF; SAFB2; MTF2; PCGF2; BRD7; SIRT7; PBX3; ZEB2; COPS2; BANP; CCDC59; KLF2; EGR4; IKBKAP; ZNF184; ZMYND8; DDX17; PIAS3; TSC22D2; PREB; LEF1; NFATC1; FOXE1; CDK7; ISL1; NCOA1; TLE1; CUX1; BCL10; PIR; ZNF160; TCERG1; TRRAP; FLNA; HNRNPD; KMT2A; CTNNB1; FUBP1; ZNF165; NKX3-1; OSR2; ZNF711; BCL11B; ARID4B; TGIF1; ARNTL2; BACH2; TCF7; MYB; BTG1; DNMT1; STAT5B; BBX; PBX1; MAF; PCGF3; ZFPM2; RREB1; MAFB; ERG; AATF; HSBP1; ZNF587; CREG1; PAX5; YWHAB; ZNF532; TOB1; NFKBIB; ZNF611; CEBPZ; NFAT5; MEIS1; EYA1; FOSL1; SUZ12; STAT3; SMAD1; MEIS2; KDM5A; AEBP1; KLF6; KDM5D; TOX3; TSC22D1; ZNF586; PEG3; THAP11