Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57771	Belinostat	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	HOXC10; SMARCD2; STAT1; FOS; HMG20B; DRAP1; PPARD; ACTL6A; FOXO4; NR3C1; RAD21; TP63; HOXC11; PPARA; DLX4; UBE2B; CREM; ASCL3; SSBP2; TOX4; ETS1; SNAI2; HOXD1; MYCBP; MED31; TAF4B; NR4A2; SNAI1; BRD4; SPIB; CD3D; ZNF331; TGFB1; NR4A3; BNC1; KLF5; HSF1; PFDN5; DDIT3; SATB2; INSM1; JUN; NR1H4; ATOH1; NFIB; PAX5; CAMTA2; PDLIM1; TRPS1; SUMO1; SUPT4H1; NR1I3; IRX5; IRF9; OVOL2; MNX1; ING4; GMNN; ZNF669; SNIP1; JUNB; TTF1; SMARCB1; FOXC1; HBP1; CBX4; ZNF224; ENY2; MED27; HSBP1; TERF1; COPS5; NR4A1; HDAC3; HLF; DNAJC2; ZNF394; SOX9; CAMTA1; ID2; PURA; MEF2D; HMGB1; TCF7; EPAS1; MED21; PROX1; ZNF665; JUP; SMAD7; USP16; SERTAD2; BAZ2A; TCEA1; ZNF44; MBD2; GATAD2A; GATA2; PEX2; TRIB3; SIX1; ZBED2; NR1D2; ETV5; JUND; RUNX3; RBBP8; SP110; RNF14; WT1; MED15; TSC22D1; FOXG1; FOXD1; NR3C2; CBX7; ZKSCAN1; ZNF14; CNBP; MXI1; HIVEP2; TRIM29; ATF3; RUVBL2; HOXC4; CALR; PHF20; KLF6; FOSB; ZNF430; FOXF1; ID1; BHLHE41; POU2AF1; MYBL1; ZNF160; CREB3L2; SUZ12; ERG; MLXIP; CEBPB; GTF2A2; SMARCA2; CRK; MYCL; TOB1; ERBB4; ZNF91; KLF9; HMGN3; KAT6A
Down-regulation	245	PCBD1; SPDEF; ZBTB1; GLI2; EZH2; DNMT3B; SOX2; VGLL4; PARP1; SOX11; PGR; TFDP1; NFKBIA; LOXL2; ERBB2; HDAC2; ZNF292; LIN28A; TCF4; GABPB1; TGFB1I1; HSF2; SALL1; E2F2; SOX17; ZNF112; PSIP1; RFX7; PLAG1; BACH1; NCOA4; MEOX2; KAT6B; WDHD1; TLE4; BASP1; HMGA2; ZEB1; AR; RERE; NSD1; UBP1; PBRM1; SOX4; FOXM1; ZFP64; PRMT2; TRIM27; FOXO1; ZFP36L2; ZNF282; NCOA2; ZNF672; ZNF516; UIMC1; CBFB; ZBTB39; MECOM; SCMH1; STAT6; MAGED1; ZNF236; ZNF692; SETDB1; AEBP1; TSC22D3; BCLAF1; ESR1; ZFHX4; TRIM24; TCF12; CDK8; MBD3; PLAGL2; GCFC2; ZNF189; DDX5; CHD3; NCOR2; EP400; SMAD3; TCF3; NONO; TRIM33; TBL1X; SMARCA5; MLLT10; BAZ1A; ZNF32; ZNF532; ELK1; ZNF467; EYA2; CHAF1B; HIPK1; ZNF710; SMARCA4; MYRF; MYB; RNF2; ZSCAN31; TP53; PMF1; ZNF184; STAT5B; SAP30; BMI1; NUP62; TAL1; GLI3; ARID3A; ETV4; ZBED1; ZKSCAN7; MEIS2; CTNNB1; SIAH2; MED16; TADA3; DDX17; CARM1; FOXA2; ZNF358; ZFX; HDAC6; DEK; KAT2B; PHF2; NCOA6; ASXL1; DNMT1; DPF2; WHSC1; HES1; KAT7; REPIN1; NFE2; DEAF1; ZNF410; TGIF1; PCGF2; FLI1; BRIP1; PAXBP1; ELF1; HNRNPD; BPTF; BAZ2B; PKNOX1; KLF1; HOXB2; CRY1; SMARCD3; ZNF85; IFI16; MITF; CCDC59; NRIP1; E2F3; BACH2; ARID4B; SMARCC1; LEF1; TGIF2; ZNF274; PATZ1; RLF; FHL2; BNC2; FOXN3; ZHX2; ALX1; AGO2; USP21; GTF3A; SP140L; HOXB6; SETD2; CSDE1; NFKB1; NANOG; EHMT2; RBPMS; TULP4; BATF; PBX1; RBBP4; ZNF512B; PREB; ZNF45; POU5F1B; NFX1; HIVEP1; MYBL2; MAFF; RBBP7; SKI; TRRAP; ZNF652; ZFPM2; SUB1; ZBTB38; PQBP1; ETV1; ZMYND8; ZNF146; HMGB3; ZMIZ2; SFMBT1; ID4; ZEB2; ZNF281; ADNP; FLNA; ZNF107; YAP1; FOXE1; MYCN; MEIS1; COPS2; ZNF211; PAX6; SP3; ELF4; APEX1; ZBTB18; NR2F2; MED14; ASCL1; ZNF131; TRIM16; HTATIP2; BBX; SHOX2; ZNF423; CEBPZ; ZFP36L1; HHEX; ZNF586; MAF; THAP11; EGR2; LITAF; KDM5D; CEBPA