Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57767	Motesanib	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	ADRB2; PDLIM1; HES1; MBD1; NR5A1; CCNH; CAMTA2; UBTF; NEUROD2; ZNF512B; KAT2B; HDAC9; AFF2; CNOT2; BNC1; AR; KDM5C; TEAD4; MYBL1; ZNF354A; SPIB; GRHL2; ZNF510; SOX9; ZNF189; UIMC1; TAF7; ARNT2; ZNF589; NR5A2; PMS1; CAPN15; MECOM; TFEC; SIN3B; TRIB3; NEUROD1; VAX2; ZBTB20; NR1H4; RXRG; TAF5L; ZBTB18; MYT1L; SHOX2; ZNF75D; EN2; NPM1; BHLHE41; ENY2; IFI16; ZNF500; DLX5; TWIST1; PCGF3; ZNF180; NR0B1; ARL2BP; ZIC1; SOX18; PROX1; ZNF266; PRRX1; GFI1; ZNF85; HABP4; FOSL1; HOXB13; ATN1; PRDM2; NPAS2; TAF9B; SOX17; NFYB; ZNF573; GMNN; ZFPM2; RNF6; ZNF148; PCGF2; IRF9; ZNF224; SIM2; ZNF140; ARNTL2; CBX3; TCF4; TFAP2A; ZNF443; ZNF430; NR1D2; ETV1; ZNF331; ERG; CTBP2; TDP2; SMAD1; CBFB; PFDN5; ZBTB16; COPS2; PBXIP1; HHEX; NRIP1; RORA; ETV5; SLC2A4RG; ELF4; ZNF44; ESR1; MAF; ZNF43; CHD9; TERF2; ZNF274; PHOX2B; NFIB; RREB1; FOSL2; KLF10; ITGB3BP; SUZ12; NFAT5; WT1; MNAT1; IRF8; NR2F6; ZMIZ1
Down-regulation	220	SMAD4; HEY1; KAT7; ZBTB39; HIC2; HSF2; FOXJ3; TBP; RRN3; KAT6B; ZNF263; KAT5; TSC22D2; KDM5B; DPF2; RBBP4; MDM4; FOXO3; GABPA; SMARCC1; KAT8; RFX7; SSRP1; ZBTB11; KLF5; IRF2; ZFP64; ZNF7; NFKBIA; SAFB; CTR9; CHD1; NRF1; SMARCA5; HIPK3; UBE2L3; GTF2A1; DNMT3B; RBM14; GTF2IRD1; ZNF202; BAZ1B; BCL6; PSMC3IP; SUPT4H1; EWSR1; ZNF516; SIX2; PSPC1; TCF12; MYCBP; MLLT10; PUF60; DR1; BRF2; ALX1; SAP18; PPP1R13L; TRAF6; ZNF384; NFE2L1; NAB1; LITAF; ASCL1; RELA; TEAD1; MEF2A; REST; TRIM28; KDM5D; USF2; KMT2A; MDM2; TAF10; SP2; TGFB1I1; SNW1; ZKSCAN7; CHD8; SMARCE1; BIRC2; BRD3; ZNF226; PIAS3; NCOR2; HBP1; ZNF410; FOXA2; PIAS4; KLF12; HTATIP2; MED13; FOXO1; KDM2A; SSBP2; ASH2L; FOXN2; BMI1; ATF6; PHF8; YAP1; HCFC2; NFATC1; RFC1; SMARCA1; NFKB1; XRCC6; HOXA11; CREB1; BAZ2B; JUP; CEBPG; ADNP; TRIM29; ELF1; CUX1; ZNF468; TOX3; SCAND1; MEOX2; MITF; TCF7L2; CLOCK; BCL3; SETD2; ZMYM2; PRKDC; NCOA1; ZBTB7A; NCOA4; BCOR; CRY1; PATZ1; TBL1XR1; TSG101; TAL1; GLI3; TRRAP; SIX3; PLAGL1; CTNNB1; PPRC1; SSX1; IKZF5; TRAK1; ISL1; CDK7; IRF1; UBE2I; AIP; SREBF1; HSF1; ZIC3; ERBB2; SIAH2; ZNF134; ZNF131; MAFF; EGR1; ZNF587; JARID2; YWHAB; MYCL; SMAD2; TCF7L1; DLX2; CCDC59; UBP1; KAT6A; SALL2; MLX; NUP62; NR3C2; PHIP; INSR; NR2F2; LIN28A; HNRNPD; TLE4; NKX2-1; RUVBL2; CHD4; ZNF239; TRIP6; STAT6; STAT3; KLF4; CCNE1; STAT5B; DNMT1; ETS2; PITX1; ID3; DACH1; BCL10; JUNB; TRIM16; HOXB2; CEBPB; NR2F1; FOXF1; ZNF652; NR2C1; HDAC1; CEBPZ; ELF5; PEX2; ARID1A; BCL11B; TSC22D1; NFKBIB; ATF3; LEF1; MAFB; CEBPA; ZNF586; THAP11; HOXC6; CITED2; NFKB2