Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57765	Saracatinib	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	PAX8; RAD21; HOXC10; CCNH; RYBP; ZBED2; YEATS4; SOX13; RRN3; BHLHE41; CCNE1; SOX17; ECD; JUNB; WWC1; HOXD1; ABT1; MED25; WT1; ZNF354A; DLX6; POU4F3; SRCAP; HOXB5; ZFHX4; SKIL; MED15; ZNF217; ZNF195; ZNF24; TRIB3; MBD2; DLX5; RARG; IRF9; ZSCAN9; ARNT2; CNOT6; SETDB1; ZNF473; MXI1; CBX2; DMRT1; BNC2; NFKBIB; ZBED4; TAF4B; GTF2IRD1; ZNF589; POU2F2; ELF3; GMEB2; ZNF668; TFDP2; SHOX2; ARID5B; ETS1; MECOM; EHF; ZNF444; CITED1; TFAP2C; HDAC9; ARNT; GMNN; BRIP1; SUMO1; SNAI2; ZNF215; ZNF146; MSC; MITF; HOXA3; CSDE1; ACTL6A; C1QBP; ZNF165; SUB1; MYRF; CDX1; SIX3; HOXD3; MEOX1; ZNF467; ASCL1; CBX4; E2F3; TAF5; CTBP2; KLF5; ESR1; ZNF580; MED13; CBX6; CREBL2; AGO2; URI1; FOXE1; CDK7; ETS2; SP140; BARX1; NAB1; ETV5; SSBP2; TAF11; NFKB2; TOX; ZNF131; SSX1; NKX2-1; DDIT3; MYBL1; IRF6; AIP; NRIP1; ELF4; E2F5; SERTAD2; TRIM29; ID2; CEBPB; ZHX2; ZNF12; KLF11; ZNF83; GATAD2A; SMAD6; DAXX; CALR; RUNX1; TSG101; CTBP1; KLF4; CHD7; DBP; MNDA; HIRA; ATF3; HOXB6; EGR1; EGR2; HOXB7; USP22; TWIST1; KLF6; ERBB4; ST18; DNMT1; MTA1
Down-regulation	184	ZNF329; TBL1X; CARM1; PSMC3IP; KAT7; SIAH2; BCLAF1; ZSCAN18; KDM5B; RBL1; TRIM24; NCOR2; ARL2BP; RFX7; BMI1; MED1; RBBP4; TGIF1; TCF4; XRCC6; MAGED1; NFIC; FOXO3; HLX; TRRAP; PMF1; ING2; CNOT1; GABPB1; LIN28A; CREM; TGFB1I1; ZNF432; JARID2; DNMT3B; RAN; CAMTA2; NCOA6; CHD1; NCOA1; ASH2L; SMARCA4; LIMD1; DDX17; BRD3; EP400; MEOX2; CITED2; CTCF; TAF6; ZNF516; FOXN3; HNRNPD; POLR2A; CBFB; BLM; ARID1A; MGA; ZNF84; BRD4; PCGF2; ZNF273; CHD9; SMAD3; BCL3; TCF20; NFIB; SMAD5; PBX1; FOXO1; ZFP64; SMARCD3; NCOR1; ZNF226; SOX11; CDC5L; NLK; ATF7IP; ZNF93; ZMIZ1; ZBED1; YBX1; FLNA; NR2F6; HSBP1; EDF1; NR2E1; TOX3; ALX1; VEZF1; ZKSCAN7; ENO1; PAX6; ZNF274; FOXG1; HIC2; SNW1; PREB; ZIC3; USP21; RCOR3; AATF; TLE4; ZMYND8; POU3F2; FOXL2; ERBB2; ZBTB16; HMGB3; ZNF32; MED24; ING1; EN1; ING3; MTF2; BCL11B; TCEA2; TAF1D; HTATIP2; POU2AF1; RBBP7; RBM14; NEDD8; NR2F1; ZBTB20; TSC22D2; KLF2; INSR; WWTR1; NR4A3; FOXA1; PHF20; PHF1; EGR4; TCF7L1; KAT6A; IRX5; CREB3L1; ARID4B; SMARCA1; ISL1; ZNF423; HMGB2; PATZ1; PITX1; BTG1; SAP30; ZNF512B; ATF4; YWHAB; SMARCC2; MEIS1; NUP62; KMT2A; TOB1; CUX1; NANOG; RCOR1; RBL2; HEY1; CEBPZ; ZNF281; BRD2; ZNF532; ZFPM2; TGFB1; ZEB2; STAT5B; STAT3; MAF; TBX3; ZNF43; KDM5D; ELK3; NFAT5; FOSL1; ZFP36L1; RUNX3; PEG3; ZBTB38; KDM5A; ZNF586; THAP11; CEBPA