Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID57764	Axitinib	GSE92742	NPC	Human	24h	10uM	EID0319

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	HOXC10; CCNH; SOX13; RAD21; CEBPD; TTF2; NPAS2; CRYM; TFAP2A; ZBTB16; NR1H4; MYBL1; CSDC2; TAF5L; HOXD1; ZXDC; MNX1; SNAPC4; TRPS1; BCL11A; SRCAP; ZNF7; ZHX2; TP73; NR5A2; TOX4; ZBED2; SKIL; PNRC1; PKNOX2; TRIB3; NCOA2; ZNF16; RING1; PRDM2; SOX3; ARNT2; PCGF1; HDAC9; ZFP36L2; ZNF34; ZNF623; TGFB1; TAF6; SIRT2; CIZ1; TFAP2C; MEIS2; CARHSP1; HOXD3; MEN1; CNOT3; ARID5B; MYRF; ZNF93; HSF1; KLF11; IRF9; ATF6; TEAD4; NELFB; PHIP; ZNF430; LHX3; SOX18; PFDN5; SLC2A4RG; ZNF467; CBX4; ATF7IP; CREB3; CDK7; PRPF6; SP110; CDK9; CBFA2T3; SALL1; ERF; ATN1; FOXG1; DYRK1B; EHF; SP140L; PSMC3; TADA3; HIVEP1; HBP1; ZNF33B; BHLHE41; GATA6; SIX3; ELF3; CAMTA1; SOX12; CREB3L2; ZNF512B; TCEA1; BTF3; SSX1; CTBP2; CEBPG; ELF5; ZKSCAN1; MED17; BNC2; PLAGL1; KAT2B; ZNF394; ADNP; GTF3A; WT1; RARA; ZNF443; ZFPM2; CSDE1; SOX17; MYB; TOX; ZNF665; CUX2; ZNF264; IRF8; GMNN; HMGB1; DACH1; ZNF44; ETV1; DNAJC2; HMGN3; LMCD1; MTF2; NFIB; NFE2L2; SPIB; HOXB13; ZIC1; ERBB4; YBX3; NR4A2; ID1; STAT4; ST18; ZNF91; MTA1
Down-regulation	180	BASP1; SPEN; SOX11; TBP; SUB1; SMAD5; DNMT3B; TBPL1; HDAC2; PURA; GABPA; PCGF2; RBBP4; RHOA; MYC; NFIL3; ZBTB1; ZNF516; MEOX2; YEATS4; FOXJ3; EED; BCLAF1; MAX; SOX2; TEAD1; POU3F2; BATF3; KLF2; HEY1; VGLL4; HSF2; TGFB1I1; RFX7; MDM4; CERS4; CBFB; ETS1; ARRB1; TCF4; SAP18; KLF12; CHD1; SIAH2; USF2; BIRC2; HOXB2; ZNF226; SREBF1; IRF2; HES1; SOX15; PSMC3IP; ZNF292; BRF2; ATF1; FOXD1; RELB; MAFF; BRD3; TFDP1; ZNF23; NCOA4; RB1; CASZ1; MDM2; BMI1; LOXL2; HMGA2; ORC2; TCF12; MYCBP; PIAS2; PHF8; ARID4A; POU4F1; MGA; SNW1; NFIX; NRIP1; SIX1; EYA2; THRAP3; REST; NR1H3; RLF; HIPK3; CCNC; HMGB3; CBX6; NUP62; ASH2L; FLI1; TBX3; SNIP1; PLAG1; TCEA2; NONO; FLNA; TBL1XR1; STAT5B; HOXA7; CREB5; ITGB3BP; TFAM; TWIST1; MITF; CTNNB1; BCL6; ASCL1; DBP; RBL2; UBE2I; HOXB6; ZNF587; NR1D2; RBBP5; KAT6A; IRF7; ISL1; HNRNPD; SMARCA1; LEF1; GTF2IRD1; WHSC1; RNF14; MED1; NFAT5; BRD8; PIAS3; NEDD8; IRX5; ZNF302; BBX; HSBP1; ZBTB38; TOX3; BTG1; DNMT1; GTF2I; ID4; PRKDC; BAZ1A; MSX1; ATF3; TXNIP; EGR1; ELK3; SCAND1; FOSL1; BCL11B; NR2F2; HLTF; KLF7; MNAT1; CERS6; NR4A1; MEIS1; PAX5; SETD2; HOXB7; EGR4; ARNTL; MAF; ZNF274; CHD7; STAT6; LITAF; ZNF532; FOXF1; SOX9; CEBPA; EGR3; MAFB; NKX3-1; KDM5D; KDM5A; NFKB2; ZNF586; PEG3